Interstitial Pressure in Pancreatic Ductal Adenocarcinoma Is Dominated by a Gel-Fluid Phase von DuFort, Christopher C., DelGiorno, Kathleen E., Carlson, Markus A., Osgood, Ryan J., Zhao, Chunmei, Huang, Zhongdong, Thompson, Curtis B., Connor, Robert J., Thanos, Christopher D., Scott Brockenbrough, J., Provenzano, Paolo P., Frost, Gregory I., Michael Shepard, H., Hingorani, Sunil R.

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Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer von Whatcott, Clifford J, Diep, Caroline H, Jiang, Ping, Watanabe, Aprill, LoBello, Janine, Sima, Chao, Hostetter, Galen, Shepard, H Michael, Von Hoff, Daniel D, Han, Haiyong

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Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression von Li, Xiaoming, Shepard, H Michael, Cowell, Jessica A, Zhao, Chunmei, Osgood, Ryan J, Rosengren, Sanna, Blouw, Barbara, Garrovillo, Sheryl A, Pagel, Mark D, Whatcott, Clifford J, Han, Haiyong, Von Hoff, Daniel D, Taverna, Darin M, LaBarre, Michael J, Maneval, Daniel C, Thompson, Curtis B

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Breaching the Castle Walls: Hyaluronan Depletion as a Therapeutic Approach to Cancer Therapy von Shepard, H Michael

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Targeting Adenosine with Adenosine Deaminase 2 to Inhibit Growth of Solid Tumors von Wang, Lin, Londono, Luz M., Cowell, Jessica, Saatci, Ozge, Aras, Mertkaya, Ersan, Pelin G., Serra, Sara, Pei, Hong, Clift, Renee, Zhao, Qiping, Phan, Kim B., Huang, Lei, LaBarre, Michael J., Li, Xiaoming, Shepard, H. Michael, Deaglio, Silvia, Linden, Joel, Thanos, Christopher D., Sahin, Ozgur, Cekic, Caglar

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Tumor-associated hyaluronan limits efficacy of monoclonal antibody therapy von Singha, Netai C, Nekoroski, Tara, Zhao, Chunmei, Symons, Rebecca, Jiang, Ping, Frost, Gregory I, Huang, Zhongdong, Shepard, H Michael

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Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models von Thompson, Curtis B, Shepard, H Michael, O'Connor, Patrick M, Kadhim, Salam, Jiang, Ping, Osgood, Ryan J, Bookbinder, Louis H, Li, Xiaoming, Sugarman, Barry J, Connor, Robert J, Nadjsombati, Sinisa, Frost, Gregory I

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Trastuzumab: dreams, desperation and hope von Shepard, H. Michael

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Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family von Shepard, H Michael, Brdlik, Cathleen M, Schreiber, Hans

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Accumulation of Extracellular Hyaluronan by Hyaluronan Synthase 3 Promotes Tumor Growth and Modulates the Pancreatic Cancer Microenvironment von Singha, Netai C., Zhao, Chunmei, Kultti, Anne, Zimmerman, Susan, Osgood, Ryan J., Symons, Rebecca, Jiang, Ping, Li, Xiaoming, Thompson, Curtis B., Infante, Jeffrey R., Jacobetz, Michael A., Tuveson, David A., Frost, Gregory I., Shepard, H. Michael, Huang, Zhongdong

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Therapeutic targeting of hyaluronan in the tumor stroma von Kultti, Anne, Li, Xiaoming, Jiang, Ping, Thompson, Curtis B, Frost, Gregory I, Shepard, H Michael

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KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions von Marella, Mathieu, Jadin, Laurence, Keller, Gilbert A, Sugarman, Barry J, Frost, Gregory I, Shepard, H Michael

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Biomarker-Driven Drug Discovery in Cancer—Trastuzumab Development: 2019 Lasker-DeBakey Clinical Medical Research Award von Shepard, H. Michael

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The Team that Just Wouldn’t Quit and a New Paradigm in Cancer Drug Discovery von Shepard, H. Michael

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Response to Chauhan et al.: Interstitial Pressure and Vascular Collapse in Pancreas Cancer—Fluids and Solids, Measurement and Meaning von DelGiorno, Kathleen E., Carlson, Markus A., Osgood, Ryan, Provenzano, Paolo P., Brockenbough, J. Scott, Thompson, Curtis B., Shepard, H. Michael, Frost, Gregory I., Potter, John D., Hingorani, Sunil R.

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Characterization of a Novel Recombinant Hyaluronan Binding Protein for Tissue Hyaluronan Detection von Jadin, Laurence, Huang, Lei, Wei, Ge, Zhao, Qiping, Gelb, Arnold B., Frost, Gregory I., Jiang, Ping, Shepard, H. Michael

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Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell von He, Yanran, Schreiber, Karin, Wolf, Steven P, Wen, Frank, Steentoft, Catharina, Zerweck, Jonathan, Steiner, Madeline, Sharma, Preeti, Shepard, H Michael, Posey, Avery, June, Carl H, Mandel, Ulla, Clausen, Henrik, Leisegang, Matthias, Meredith, Stephen C, Kranz, David M, Schreiber, Hans

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Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer von Hingorani, Sunil R, Harris, William P, Beck, J Thaddeus, Berdov, Boris A, Wagner, Stephanie A, Pshevlotsky, Eduard M, Tjulandin, Sergei A, Gladkov, Oleg A, Holcombe, Randall F, Korn, Ronald, Raghunand, Natarajan, Dychter, Samuel, Jiang, Ping, Shepard, H Michael, Devoe, Craig E

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Developments in therapy with monoclonal antibodies and related proteins von Shepard, H Michael, Phillips, Gail Lewis, Thanos, Christopher D, Feldmann, Marc

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Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours von Infante, Jeffrey R, Korn, Ronald L, Rosen, Lee S, LoRusso, Patricia, Dychter, Samuel S, Zhu, Joy, Maneval, Daniel C, Jiang, Ping, Shepard, H Michael, Frost, Gregory, Von Hoff, Daniel D, Borad, Mitesh J, Ramanathan, Ramesh K

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