Amyloid beta： structure, biology and structure-based therapeutic development von Chen, Guo-fang, Xu, Ting-hai, Yan, Yan, Zhou, Yu-ren, Jiang, Yi, Melcher, Karsten, Xu, H Eric

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Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin von Yin, Wanchao, Luan, Xiaodong, Li, Zhihai, Zhou, Ziwei, Wang, Qingxing, Gao, Minqi, Wang, Xiaoxi, Zhou, Fulai, Shi, Jingjing, You, Erli, Liu, Mingliang, Wang, Qingxia, Jiang, Yi, Jiang, Hualiang, Xiao, Gengfu, Zhang, Leike, Yu, Xuekui, Zhang, Shuyang, Eric Xu, H.

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Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase von Byun, Sangwon, Seok, Sunmi, Kim, Young-Chae, Zhang, Yang, Yau, Peter, Iwamori, Naoki, Xu, H. Eric, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim

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Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir von Yin, Wanchao, Mao, Chunyou, Luan, Xiaodong, Shen, Dan-Dan, Shen, Qingya, Su, Haixia, Wang, Xiaoxi, Zhou, Fulai, Zhao, Wenfeng, Gao, Minqi, Chang, Shenghai, Xie, Yuan-Chao, Tian, Guanghui, Jiang, He-Wei, Tao, Sheng-Ce, Shen, Jingshan, Jiang, Yi, Jiang, Hualiang, Xu, Yechun, Zhang, Shuyang, Zhang, Yan, Xu, H. Eric

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Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy von Duan, Jia, Shen, Dan-dan, Zhou, X. Edward, Bi, Peng, Liu, Qiu-feng, Tan, Yang-xia, Zhuang, You-wen, Zhang, Hui-bing, Xu, Pei-yu, Huang, Si-Jie, Ma, Shan-shan, He, Xin-heng, Melcher, Karsten, Zhang, Yan, Xu, H. Eric, Jiang, Yi

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Structure and dynamics of the active human parathyroid hormone receptor-1 von Zhao, Li-Hua, Ma, Shanshan, Sutkeviciute, Ieva, Shen, Dan-Dan, Zhou, X Edward, de Waal, Parker W, Li, Chen-Yao, Kang, Yanyong, Clark, Lisa J, Jean-Alphonse, Frederic G, White, Alex D, Yang, Dehua, Dai, Antao, Cai, Xiaoqing, Chen, Jian, Li, Cong, Jiang, Yi, Watanabe, Tomoyuki, Gardella, Thomas J, Melcher, Karsten, Wang, Ming-Wei, Vilardaga, Jean-Pierre, Xu, H Eric, Zhang, Yan

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Structural biology of G protein‐coupled receptor signaling complexes von Edward Zhou, X., Melcher, Karsten, Eric Xu, H.

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A complex structure of arrestin-2 bound to a G protein-coupled receptor von Yin, Wanchao, Li, Zhihai, Jin, Mingliang, Yin, Yu-Ling, de Waal, Parker W., Pal, Kuntal, Yin, Yanting, Gao, Xiang, He, Yuanzheng, Gao, Jing, Wang, Xiaoxi, Zhang, Yan, Zhou, Hu, Melcher, Karsten, Jiang, Yi, Cong, Yao, Edward Zhou, X., Yu, Xuekui, Eric Xu, H.

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Structural basis of leukotriene B4 receptor 1 activation von Wang, Na, He, Xinheng, Zhao, Jing, Jiang, Hualiang, Cheng, Xi, Xia, Yu, Eric Xu, H., He, Yuanzheng

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Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor von Wang, Yue, Guo, Shimeng, Zhuang, Youwen, Yun, Ying, Xu, Peiyu, He, Xinheng, Guo, Jia, Yin, Wanchao, Xu, H. Eric, Xie, Xin, Jiang, Yi

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Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors von Zhao, Fenghui, Zhou, Qingtong, Cong, Zhaotong, Hang, Kaini, Zou, Xinyu, Zhang, Chao, Chen, Yan, Dai, Antao, Liang, Anyi, Ming, Qianqian, Wang, Mu, Chen, Li-Nan, Xu, Peiyu, Chang, Rulve, Feng, Wenbo, Xia, Tian, Zhang, Yan, Wu, Beili, Yang, Dehua, Zhao, Lihua, Xu, H. Eric, Wang, Ming-Wei

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Structure and Physiological Regulation of AMPK von Yan, Yan, Zhou, X Edward, Xu, H Eric, Melcher, Karsten

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Structural insights into the peptide selectivity and activation of human neuromedin U receptors von You, Chongzhao, Zhang, Yumu, Xu, Peiyu, Huang, Sijie, Yin, Wanchao, Eric Xu, H., Jiang, Yi

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Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex von Xing, Changrui, Zhuang, Youwen, Xu, Ting-Hai, Feng, Zhiwei, Zhou, X. Edward, Chen, Maozi, Wang, Lei, Meng, Xing, Xue, Ying, Wang, Junmei, Liu, Heng, McGuire, Terence Francis, Zhao, Gongpu, Melcher, Karsten, Zhang, Cheng, Xu, H. Eric, Xie, Xiang-Qun

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Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors von Duan, Jia, Shen, Dan-Dan, Zhao, Tingting, Guo, Shimeng, He, Xinheng, Yin, Wanchao, Xu, Peiyu, Ji, Yujie, Chen, Li-Nan, Liu, Jinyu, Zhang, Huibing, Liu, Qiufeng, Shi, Yi, Cheng, Xi, Jiang, Hualiang, Eric Xu, H., Zhang, Yan, Xie, Xin, Jiang, Yi

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Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2 von Zhuang, Youwen, Wang, Lei, Guo, Jia, Sun, Dapeng, Wang, Yue, Liu, Weiyi, Xu, H. Eric, Zhang, Cheng

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Androgen receptor： structure, role in prostate cancer and drug discovery von Tan, MH Eileen, Li, Jun, Xu, H Eric, Melcher, Karsten, Yong, Eu-leong

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Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 von Xie, Yuanchao, Yin, Wanchao, Zhang, Yumin, Shang, Weijuan, Wang, Zhen, Luan, Xiaodong, Tian, Guanghui, Aisa, Haji A., Xu, Yechun, Xiao, Gengfu, Li, Jia, Jiang, Hualiang, Zhang, Shuyang, Zhang, Leike, Xu, H. Eric, Shen, Jingshan

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Structural basis for the tethered peptide activation of adhesion GPCRs von Ping, Yu-Qi, Xiao, Peng, Yang, Fan, Zhao, Ru-Jia, Guo, Sheng-Chao, Yan, Xu, Wu, Xiang, Zhang, Chao, Lu, Yan, Zhao, Fenghui, Zhou, Fulai, Xi, Yue-Tong, Yin, Wanchao, Liu, Feng-Zhen, He, Dong-Fang, Zhang, Dao-Lai, Zhu, Zhong-Liang, Jiang, Yi, Du, Lutao, Feng, Shi-Qing, Schöneberg, Torsten, Liebscher, Ines, Xu, H. Eric, Sun, Jin-Peng

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MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function von Fu, Ting, Seok, Sunmi, Choi, Sunge, Huang, Zhang, Suino-Powell, Kelly, Xu, H. Eric, Kemper, Byron, Kemper, Jongsook Kim

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