Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agents von Peltonen, Karita, Colis, Laureen, Liu, Hester, Jäämaa, Sari, Moore, Henna M, Enbäck, Juulia, Laakkonen, Pirjo, Vaahtokari, Anne, Jones, Richard J, af Hällström, Taija M, Laiho, Marikki

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Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer von Saeed, Khalid, Rahkama, Vesa, Eldfors, Samuli, Bychkov, Dmitry, Mpindi, John Patrick, Yadav, Bhagwan, Paavolainen, Lassi, Aittokallio, Tero, Heckman, Caroline, Wennerberg, Krister, Peehl, Donna M, Horvath, Peter, Mirtti, Tuomas, Rannikko, Antti, Kallioniemi, Olli, Östling, Päivi, af Hällström, Taija M

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Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress von Peltonen, Karita, Colis, Laureen, Liu, Hester, Jäämaa, Sari, Zhang, Zhewei, Af Hällström, Taija, Moore, Henna M, Sirajuddin, Paul, Laiho, Marikki

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Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices von Davies, Emma J., Dong, Meng, Gutekunst, Matthias, Närhi, Katja, van Zoggel, Hanneke J. A. A., Blom, Sami, Nagaraj, Ashwini, Metsalu, Tauno, Oswald, Eva, Erkens-Schulze, Sigrun, Delgado San Martin, Juan A., Turkki, Riku, Wedge, Stephen R., af Hällström, Taija M., Schueler, Julia, van Weerden, Wytske M., Verschuren, Emmy W., Barry, Simon T., van der Kuip, Heiko, Hickman, John A.

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Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient‐derived cancer cells von Saeed, Khalid, Ojamies, Poojitha, Pellinen, Teijo, Eldfors, Samuli, Turkki, Riku, Lundin, Johan, Järvinen, Petrus, Nisen, Harry, Taari, Kimmo, af Hällström, Taija M., Rannikko, Antti, Mirtti, Tuomas, Kallioniemi, Olli, Östling, Päivi

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Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes von Puhka, Maija, Takatalo, Maarit, Nordberg, Maria-Elisa, Valkonen, Sami, Nandania, Jatin, Aatonen, Maria, Yliperttula, Marjo, Laitinen, Saara, Velagapudi, Vidya, Mirtti, Tuomas, Kallioniemi, Olli, Rannikko, Antti, Siljander, Pia R-M, Af Hällström, Taija Maria

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Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras‐driven lung tumours von Närhi, Katja, Nagaraj, Ashwini S, Parri, Elina, Turkki, Riku, van Duijn, Petra W, Hemmes, Annabrita, Lahtela, Jenni, Uotinen, Virva, Mäyränpää, Mikko I, Salmenkivi, Kaisa, Räsänen, Jari, Linder, Nina, Trapman, Jan, Rannikko, Antti, Kallioniemi, Olli, Af Hällström, Taija M, Lundin, Johan, Sommergruber, Wolfgang, Anders, Simon, Verschuren, Emmy W

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Novel Assay to Detect RNA Polymerase I Activity In Vivo von Guner, Gunes, Sirajuddin, Paul, Zheng, Qizhi, Bai, Baoyan, Brodie, Alexandra, Liu, Hester, Af Hällström, Taija, Kulac, Ibrahim, Laiho, Marikki, De Marzo, Angelo M

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MicroRNA-mediated suppression of oncolytic adenovirus replication in human liver von Ylösmäki, Erkko, Lavilla-Alonso, Sergio, Jäämaa, Sari, Vähä-Koskela, Markus, af Hällström, Taija, Hemminki, Akseli, Arola, Johanna, Mäkisalo, Heikki, Saksela, Kalle

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Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement von Kiviharju-af Hällström, Taija M, Jäämaa, Sari, Mönkkönen, Mia, Peltonen, Karita, Andersson, Leif C, Medema, René H, Peehl, Donna M, Laiho, Marikki

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PSA forms complexes with α1-antichymotrypsin in prostate von Zhu, Lei, Jäämaa, Sari, af Hällström, Taija M., Laiho, Marikki, Sankila, Anna, Nordling, Stig, Stenman, Ulf-Håkan, Koistinen, Hannu

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Differential epithelium DNA damage response to ATM and DNA-PK pathway inhibition in human prostate tissue culture von Zhang, Zhewei, Yang, Zhiming, Jäämaa, Sari, Liu, Hester, Pellakuru, Laxmi G., Iwata, Tsuyoshi, af Hällström, Taija M., De Marzo, Angelo M., Laiho, Marikki

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Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation von Rajecki, Maria, Hällström, Taija af, Hakkarainen, Tanja, Nokisalmi, Petri, Hautaniemi, Sampsa, Nieminen, Anni I., Tenhunen, Mikko, Rantanen, Ville, Desmond, Reneé A., Chen, Dung‐Tsa, Guse, Kilian, Stenman, Ulf‐Håkan, Gargini, Ricardo, Kapanen, Mika, Klefström, Juha, Kanerva, Anna, Pesonen, Sari, Ahtiainen, Laura, Hemminki, Akseli

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Genetic changes and DNA damage responses in the prostate von Kiviharju-af Hällström, Taija M., Laiho, Marikki

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Multicenter Evaluation of Circulating Plasma MicroRNA Extraction Technologies for the Development of Clinically Feasible Reverse Transcription Quantitative PCR and Next-Generation... von Kloten, Vera, Neumann, Martin H D, Di Pasquale, Francesca, Sprenger-Haussels, Markus, Shaffer, Jonathan M, Schlumpberger, Martin, Herdean, Andrei, Betsou, Fay, Ammerlaan, Wim, Af Hällström, Taija, Serkkola, Elina, Forsman, Tarja, Lianidou, Evi, Sjöback, Robert, Kubista, Mikael, Bender, Sebastian, Lampignano, Rita, Krahn, Thomas, Schlange, Thomas

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Exploration of Extracellular Vesicle miRNAs, Targeted mRNAs and Pathways in Prostate Cancer: Relation to Disease Status and Progression von Puhka, Maija, Thierens, Lisse, Nicorici, Daniel, Forsman, Tarja, Mirtti, Tuomas, Af Hällström, Taija, Serkkola, Elina, Rannikko, Antti

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Pre‐analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients von Schneegans, Svenja, Lück, Lelia, Besler, Katharina, Bluhm, Leonie, Stadler, Julia‐Christina, Staub, Janina, Greinert, Rüdiger, Volkmer, Beate, Kubista, Mikael, Gebhardt, Christoffer, Sartori, Alexander, Irwin, Darryl, Serkkola, Elina, Hällström, Taija, Lianidou, Evi, Sprenger‐Haussels, Markus, Hussong, Melanie, Mohr, Peter, Schneider, Stefan W., Shaffer, Jonathan, Pantel, Klaus, Wikman, Harriet

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Urinary extracellular vesicles: Assessment of pre‐analytical variables and development of a quality control with focus on transcriptomic biomarker research von Barreiro, Karina, Dwivedi, Om Prakash, Valkonen, Sami, Groop, Per‐Henrik, Tuomi, Tiinamaija, Holthofer, Harry, Rannikko, Antti, Yliperttula, Marjo, Siljander, Pia, Laitinen, Saara, Serkkola, Elina, af Hällström, Taija, Forsblom, Carol, Groop, Leif, Puhka, Maija

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Contrasting DNA damage checkpoint responses in epithelium of the human seminal vesicle and prostate von Jäämaa, Sari, Sankila, Anna, Rantanen, Ville, Peltonen, Karita, Järvinen, Päivi M., af Hällström, Taija M., Ruutu, Mirja, Taari, Kimmo, Andersson, Leif C., Laiho, Marikki

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DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue von JÄÄMAA, Sari, AF HÄLLSTRÖM, Taija M, RUUTU, Mirja, ANDERSSON, Leif C, LAIHO, Marikki, SANKILA, Anna, RANTANEN, Ville, KOISTINEN, Hannu, STENMAN, Ulf-Håkan, ZHEWEI ZHANG, ZHIMING YANG, DE MARZO, Angelo M, TAARI, Kimmo

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