Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples von CLOOS, J, GOEMANS, B. F, CREUTZIG, U, SCHUURHUIS, G. J, ZWAAN, Ch. M, KASPERS, G. J. L, HESS, C. J, VAN OOSTVEEN, J. W, WAISFISZ, Q, CORTHALS, S, DE LANGE, D, BOECKX, N, HÄHLEN, K, REINHARDT, D

Volltext

Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia von GOEMANS, B. F, ZWAAN, Ch. M, KASPERS, G. J. L, HEINRICH, M. C, MILLER, M, ZIMMERMANN, M, HARLOW, A, MESHINCHI, S, LOONEN, A. H, HIHLEN, K, REINHARDT, D, CREUTZIG, U

Volltext

Causes of death - other than progressive leukemia - in childhood acute lymphoblastic (ALL) and myeloid leukemia (AML): the Dutch Childhood Oncology Group experience von SLATS, A. M, EGELER, R. M, VAN DER DOES-VAN DEN BERG, A, KORBIJN, C, HÄHLEN, K, KAMPS, W. A, VEERMAN, A. J. P, ZWAAN, C. M

Volltext

Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitat... von VAN DER VELDEN, V. H. J, WILLEMSE, M. J, VAN DER SCHOOT, C. E, HÄHLEN, K, VAN WERING, E. R, VAN DONGEN, J. J. M

Volltext

Large interindividual differences in cellular sensitivity to calicheamicin may influence gemtuzumab ozogamicin response in acute myeloid leukemia von Goemans, B F, Zwaan, C M, Vijverberg, S J H, Loonen, A H, Creutzig, U, Hählen, K, Reinhardt, D, Gibson, B E S, Cloos, J, Kaspers, G J L

Volltext

Minimal residual disease levels in bone marrow and peripheral blood are comparable in children with T cell acute lymphoblastic leukemia (ALL), but not in precursor-B-ALL von VAN DER VELDEN, V. H. J, JACOBS, D. C. H, WIJKHUIJS, A. J. M, COMANS-BITTER, W. M, WILLEMSE, M. J, HÄHLEN, K, KAMPS, W. A, VAN WERING, E. R, VAN DONGEN, J. J. M

Volltext

Treatment strategy and results in children treated on three Dutch Childhood Oncology Group acute myeloid leukemia trials von Kardos, G, Zwaan, C M, Kaspers, G J L, de-Graaf, S S N, de Bont, E S J M, Postma, A, Bökkerink, J P M, Weening, R S, van der Does-van den Berg, A, van Wering, E R, Korbijn, C, Hählen, K

Volltext

High cure rate with a moderately intensive treatment regimen in non-high-risk childhood acute lymphoblastic leukemia. Results of protocol ALL VI from the Dutch Childhood Leukemia S... von VEERMAN, A. J. P, HÄHLEN, K, KAMPS, W. A, VAN LEEUWEN, E. F, DE VAAN, G. A. M, SALBU, G, SUCIU, S, VAN WERING, E. R, VAN DER DOES-VAN DEN BERG, A

Volltext

Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias : alternative PCR targets for detection o... von SZCZEPANSKI, T, BEISHUIZEN, A, PONGERS-WILLEMSE, M. J, HÄHLEN, K, VAN WERING, E. R, WIJKHUIJS, A. J. M, TIBBE, G. J. M, DE BRUIJN, M. A. C, VAN DONGEN, J. J. M

Volltext

Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia von Zwaan, Christian M., Kaspers, Gert-Jan L., Pieters, Rob, Woerden, Nicole L. Ramakers-Van, den Boer, Monique L., Wünsche, Renate, Rottier, Maria M.A., Hählen, Karel, van Wering, Elizabeth R., Janka-Schaub, Gritta E., Creutzig, Ursula, Veerman, Anjo J.P.

Volltext

Gemtuzumab ozogamicin in pediatric CD33-positive acute lymphoblastic leukemia: first clinical experiences and relation with cellular sensitivity to single agent calicheamicin von Zwaan, C M, Reinhardt, D, Jürgens, H, Huismans, D R, Hählen, K, Smith, O P, Biondi, A, van Wering, E R, Feingold, J, Kaspers, G J L

Volltext

TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia von WOERDEN, N. L. R.-V, PIETERS, R, HÄHLEN, K, SCHMIEGELOW, K, JANKA-SCHAUB, G. E, VEERMAN, A. J. P, LOONEN, A. H, HUBEEK, I, VAN DRUNEN, E, BEVERLOO, H. B, SLATER, R. M, HARBOTT, J, SEYFARTH, J, VAN WERING, E. R

Volltext

Extramedullary infiltrates at diagnosis have no prognostic significance in children with acute myeloid leukaemia von BISSCHOP, M. M, REVESZ, T, BIERINGS, M, VAN WEERDEN, J. F, VAN WERING, E. R, HÄHLEN, K, VAN DER DOES-VAN DEN BERG, A

Volltext

Differences in the prevalence of PTPN11 mutations in FAB M5 paediatric acute myeloid leukaemia von Goemans, B. F., Zwaan, Ch. M., Martinelli, S., Harrell, P., Lange, D., Carta, C., Reinhardt, D., Hählen, K., Creutzig, U., Tartaglia, M., Heinrich, M. C., Kaspers, G. J. L.

Volltext

Intensive Treatment of Children With Acute Lymphoblastic Leukemia According to ALL-BFM-86 Without Cranial Radiotherapy: Results of Dutch Childhood Leukemia Study Group Protocol ALL... von Kamps, W.A., Bökkerink, J.P.M., Hählen, K., Hermans, J., Riehm, H., Gadner, H., Schrappe, M., Slater, R., van den Berg-de Ruiter, E., Smets, L.A., de Vaan, G.A.M., Weening, R.S., van Weerden, J.F., van Wering, E.R., den Berg, A. van der Does-van

Volltext

A comparison of the in vitro cytotoxicity of daunorubicin and liposomal daunorubicin in pediatric acute leukemia von Goemans, BF, Zwaan, CM, Reinhardt, D, Gibson, BE, Hahlen, K, Kaspers, GJ

Volltext

In Vitro Cellular Drug Resistance in Children With Relapsed/Refractory Acute Lymphoblastic Leukemia von Klumper, Edwin, Pieters, Rob, Veerman, Anjo J.P., Huismans, Dieuwke R., Loonen, Annemarie H., Hahlen, Karel, Kaspers, Gertjan J.L., van Wering, Elisabeth R., Hartmann, Reinhard, Henze, Günter

Volltext

Regeneration pattern of precursor-B-cells in bone marrow of acute lymphoblastic leukemia patients depends on the type of preceding chemotherapy von VAN LOCHEM, E. G, WIEGERS, Y. M, VAN DEN BEEMD, R, HÄHLEN, K, VAN DONGEN, J. J. M, HOOIJKAAS, H

Volltext

Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia von KAAIJK, P, KASPERS, G. J. L, VEERMAN, A. J. P, VAN WERING, E. R, BROEKEMA, G. J, LOONEN, A. H, HÄHLEN, K, SCHMIEGELOW, K, JANKA-SCHAUB, G. E, HENZE, G, CREUTZIG, U

Volltext

The Baxα:Bcl‐2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia von Salomons, Gajja S., Brady, Hugh J.M., Verwijs‐Janssen, Manon, Van Den Berg, Joop D., Hart, Augustinus A.M., Van Den Berg, Henk, Behrendt, Henk, Hahlen, Karel, Smets, Lou A.

Volltext