Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia von Tartaglia, Marco, Niemeyer, Charlotte M, Fragale, Alessandra, Song, Xiaoling, Buechner, Jochen, Jung, Andreas, Hählen, Karel, Hasle, Henrik, Licht, Jonathan D, Gelb, Bruce D

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Long-Term Outcome in Children With Relapsed ALL by Risk-Stratified Salvage Therapy: Results of Trial Acute Lymphoblastic Leukemia-Relapse Study of the Berlin-Frankfurt-Münster Grou... von EINSIEDEL, Hagen Graf, VON STACKELBERG, Arend, LUDWIG, Wolf-Dieter, HENZE, Günter, HARTMANN, Reinhard, FENGLER, Rudiger, SCHRAPPE, Martin, JANKA-SCHAUB, Gritta, MANN, Georg, HAHLEN, Karel, GOBEL, Ulrich, KLINGEBIEL, Thomas

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Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia von ROTS, M. G, PIETERS, R, PETERS, G. J, NOORDHUIS, P, VAN ZANTWIJK, C. H, KASPERS, G. J. L, HÄHLEN, K, CREUTZIG, U, VEERMAN, A. J. P, JANSEN, G

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Potential for Cure by Chemotherapy Only, without Allogeneic Stem Cell Transplantation, in Pediatric Relapsed Acute Myeloid Leukemia? von Kaspers, Gertjan J., Goemans, Bianca F., Korbijn, Carin, Tamminga, Rienk Y., Hählen, Karel

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Vascular Endothelial Growth Factor Secretion Is an Independent Prognostic Factor for Relapse-free Survival in Pediatric Acute Myeloid Leukemia Patients von de Bont, Eveline S J M, Fidler, Vaclav, Meeuwsen, Tiny, Scherpen, Frank, Hählen, Karel, Kamps, Willem A

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Addition of PTK787/ZK 222584 Can Lower the Dosage of Amsacrine To Achieve Equal Amounts of AML Cell Death von Weidenaar, Alida C., de Jonge, Hendrik J.M., Fidler, Vaclav, Elst, Arja ter, Meeuwsen, Tiny, Douwes, Jenny, Bouma, Jessica C.A., Hählen, Karel, Kamps, Willem A., de Bont, Evelina S.

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CNS-Involvement in Pediatric Acute Myeloid Leukemia: Role of Low Blast Count and Traumatic Lumbar Puncture. A Dutch Childhood Oncology Group (DCOG) Study von Zwaan, Christian M., Nix, Wendy M.L.C., Hählen, Karel, Van Wering, Elisabeth

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In-Vitro Cytotoxicity of Tipifarnib (Zarnestra TM) in Pediatric AML and ALL Samples Is Independent of RAS Mutations von Goemans, Bianca F., Zwaan, Christian M., Kaspers, Gertjan J.L., Hählen, Karel, Reinhardt, Dirk, Creutzig, Ursula, Heinrich, Michael C.

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FLT3/Internal Tandem Duplication in Paired Presentation and Relapse Pediatric AML Samples von Cloos, Jacqueline, Zwaan, Christian M., Corthals, Sophie L., Goemans, Bianca F., Waisfisz, Quinten, Creutzig, Ursula, Reinhardt, Dirk, Hählen, Karel, Kaspers, Gertjan J.L.

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Effect of childhood cancer treatment on fertility markers in adult male long-term survivors von van Casteren, Niels J., van der Linden, Geert H.M., Hakvoort-Cammel, Friederike G.A.J., Hählen, Karel, Dohle, Gert R., van den Heuvel-Eibrink, Marry M.

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Circumvention of Methotrexate Resistance in Childhood Leukemia Subtypes by Rationally Designed Antifolates von Rots, Marianne G., Pieters, Rob, Peters, Godefridus J., van Zantwijk, Christina H., Mauritz, Rob, Noordhuis, Paul, Willey, James C., Ha¨hlen, Karel, Creutzig, Ursula, Janka-Schaub, Gritta, Kaspers, Gertjan J.L., Veerman, Anjo J.P., Jansen, Gerrit

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FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657 von Goemans, Bianca F, Zwaan, Christian M, Cloos, Jacqueline, de Lange, Desiree, Loonen, Anne H, Reinhardt, Dirk, Hählen, Karel, Gibson, Brenda E.S, Creutzig, Ursula, Kaspers, Gertjan J.L

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FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance von Zwaan, Christian M., Meshinchi, Soheil, Radich, Jerald P., Veerman, AnjoJ.P., Huismans, Dieuwke R., Munske, Leonhard, Podleschny, Martina, Hählen, Karel, Pieters, Rob, Zimmermann, Martin, Reinhardt, Dirk, Harbott, Jochen, Creutzig, Ursula, Kaspers, GertjanJ.L., Griesinger, Frank

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Altered bone mineral density and body composition, and increased fracture risk in childhood acute lymphoblastic leukemia von van der Sluis, Inge M., van den Heuvel-Eibrink, Marry M., Hählen, Karel, Krenning, Eric P., de Muinck Keizer-Schrama, Sabine M.P.F.

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Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia? von Zwaan, Christian Michel, den Boer, Monique L., Kazemier, Karin M., Hählen, Karel, Loonen, Anne H., Reinhardt, Dirk, Creutzig, Ursula, Kaspers, Gertjan J.L., Pieters, Rob

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In Vitro Cellular Drug Resistance in Children With Relapsed/Refractory Acute Lymphoblastic Leukemia von Klumper, Edwin, Pieters, Rob, Veerman, Anjo J.P., Huismans, Dieuwke R., Loonen, Annemarie H., Hahlen, Karel, Kaspers, Gertjan J.L., van Wering, Elisabeth R., Hartmann, Reinhard, Henze, Günter

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The Baxα:Bcl‐2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia von Salomons, Gajja S., Brady, Hugh J.M., Verwijs‐Janssen, Manon, Van Den Berg, Joop D., Hart, Augustinus A.M., Van Den Berg, Henk, Behrendt, Henk, Hahlen, Karel, Smets, Lou A.

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Outcome for children with relapsed acute myeloid leukemia in the Netherlands following initial treatment between 1980 and 1998: survival after chemotherapy only? von Goemans, Bianca F, Tamminga, Rienk Y J, Corbijn, Carin M, Hählen, Karel, Kaspers, Gertjan J L

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Protection against chemotherapy induced mucositis by TGF-β2 in childhood cancer patients: Results from a randomized cross-over study von de Koning, Barbara A.E., Philipsen-Geerling, Bertine, Hoijer, Maarten, Hählen, Karel, Büller, Hans A., Pieters, Rob

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Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome von Zwaan, Christian M., Kaspers, Gertjan J.L., Pieters, Rob, Hählen, Karel, Janka-Schaub, Gritta E., van Zantwijk, Christina H., Huismans, Dieuwke R., de Vries, Esther, Rots, Marianne G., Peters, Godefridus J., Jansen, Gerrit, Creutzig, Ursula, Veerman, Anjo J.P.

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