Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance von Quanz, Maria, Bender, Eckhard, Kopitz, Charlotte, Grünewald, Sylvia, Schlicker, Andreas, Schwede, Wolfgang, Eheim, Ashley, Toschi, Luisella, Neuhaus, Roland, Richter, Carmen, Toedling, Joern, Merz, Claudia, Lesche, Ralf, Kamburov, Atanas, Siebeneicher, Holger, Bauser, Marcus, Hägebarth, Andrea

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The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models von Lemos, Clara, Schulze, Volker K., Baumgart, Simon J., Nevedomskaya, Ekaterina, Heinrich, Tobias, Lefranc, Julien, Bader, Benjamin, Christ, Clara D., Briem, Hans, Kuhnke, Lara P., Holton, Simon J., Bömer, Ulf, Lienau, Philip, von Nussbaum, Franz, Nising, Carl F., Bauser, Marcus, Hägebarth, Andrea, Mumberg, Dominik, Haendler, Bernard

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Identification of KCa3.1 Channel as a Novel Regulator of Oxidative Phosphorylation in a Subset of Pancreatic Carcinoma Cell Lines von Kovalenko, Ilya, Glasauer, Andrea, Schöckel, Laura, Sauter, Daniel R P, Ehrmann, Alexander, Sohler, Florian, Hägebarth, Andrea, Novak, Ivana, Christian, Sven

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Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth von Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter Hgm, Kopitz, Charlotte, Koopman, Werner Jh, Héroult, Mélanie

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BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling‐dependent tumor growth in mouse models von Politz, Oliver, Siegel, Franziska, Bärfacker, Lars, Bömer, Ulf, Hägebarth, Andrea, Scott, William J., Michels, Martin, Ince, Stuart, Neuhaus, Roland, Meyer, Kirstin, Fernández‐Montalván, Amaury Ernesto, Liu, Ningshu, von Nussbaum, Franz, Mumberg, Dominik, Ziegelbauer, Karl

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Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity von Vriens, Kim, Christen, Stefan, Parik, Sweta, Broekaert, Dorien, Yoshinaga, Kazuaki, Talebi, Ali, Dehairs, Jonas, Escalona-Noguero, Carmen, Schmieder, Roberta, Cornfield, Thomas, Charlton, Catriona, Romero-Pérez, Laura, Rossi, Matteo, Rinaldi, Gianmarco, Orth, Martin F., Boon, Ruben, Kerstens, Axelle, Kwan, Suet Ying, Faubert, Brandon, Méndez-Lucas, Andrés, Kopitz, Charlotte C., Chen, Ting, Fernandez-Garcia, Juan, Duarte, João A. G., Schmitz, Arndt A., Steigemann, Patrick, Najimi, Mustapha, Hägebarth, Andrea, Van Ginderachter, Jo A., Sokal, Etienne, Gotoh, Naohiro, Wong, Kwok-Kin, Verfaillie, Catherine, Derua, Rita, Munck, Sebastian, Yuneva, Mariia, Beretta, Laura, DeBerardinis, Ralph J., Swinnen, Johannes V., Hodson, Leanne, Cassiman, David, Verslype, Chris, Christian, Sven, Grünewald, Sylvia, Grünewald, Thomas G. P., Fendt, Sarah-Maria

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Abstract 665: Inhibition of mitochondrial complex I enhances the therapeutic benefit of BRAF inhibition in mutant melanoma cell lines von Schoeckel, Laura, Bitschar, Katharina, Héroult, Mélanie, Kopitz, Charlotte, Hägebarth, Andrea

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Abstract 5866: Discovery and profiling of a highly potent and selective ERK5 inhibitor: BAY-885 von Lemos, Clara, Nguyen, Duy, Wortmann, Lars, Bömer, Ulf, Holton, Simon, Lechner, Christian, Prechtl, Stefan, Sülzle, Detlev, Siegel, Franziska, Mumberg, Dominik, Bauser, Marcus, Hägebarth, Andrea

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Identification of K.sub.Ca3.1 Channel as a Novel Regulator of Oxidative Phosphorylation in a Subset of Pancreatic Carcinoma Cell Lines von Kovalenko, Ilya, Glasauer, Andrea, Schöckel, Laura, Sauter, Daniel R. P, Ehrmann, Alexander, Sohler, Florian, Hägebarth, Andrea, Novak, Ivana, Christian, Sven

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Abstract 772: Anti-tumor efficacy of the selective pan-FGFR Inhibitor BAY 1163877 in preclinical squamous cell carcinoma models of different origin von Héroult, Mélanie, Ocker, Matthias, Kopitz, Charlotte, Zopf, Dieter, Hägebarth, Andrea, Ziegelbauer, Karl, Ince, Stuart, Ellinghaus, Peter

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Abstract 5873: BAY-3827, a selective inhibitor of AMPK for the evaluation of the role of AMPK in Myc-dependent tumors von Lemos, Clara, Schulze, Volker K., Bader, Benjamin, Christ, Clara D., Briem, Hans, Politz, Oliver, Prinz, Florian, Holton, Simon, Heinrich, Tobias, Lefranc, Julien, Lienau, Philip, Scholz, Arne, Nussbaum, Franz von, Nising, Carl Friedrich, Mumberg, Dominik, Bauser, Marcus, Hägebarth, Andrea

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Abstract 3383: Inhibition of Akt signaling: a strategy to overcome platinum resistance in ovarian cancer von Meier, Julia C., Haendler, Bernard, Sommer, Anette, Hägebarth, Andrea, Beckmann, Georg, Kreft, Bertolt, Ziegelbauer, Karl, Kopitz, Charlotte C.

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Expression analysis of proline rich 15 (Prr15) in mouse and human gastrointestinal tumors von Meunier, Dominique, Patra, Kalicharan, Smits, Ron, Hägebarth, Andrea, Lüttges, Angela, Jaussi, Rolf, Wieduwilt, Matthew J., Quintanilla-Fend, Leticia, Himmelbauer, Heinz, Fodde, Riccardo, Fundele, Reinald H.

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Additional file 2: Figure S2. of Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth von Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter, Kopitz, Charlotte, Koopman, Werner, Héroult, Mélanie

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Additional file 1: Figure S1. of Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth von Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter, Kopitz, Charlotte, Koopman, Werner, Héroult, Mélanie

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Additional file 3: Figure S3. of Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth von Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter, Kopitz, Charlotte, Koopman, Werner, Héroult, Mélanie

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Additional file 4: Figure S4. of Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth von Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter, Kopitz, Charlotte, Koopman, Werner, Héroult, Mélanie

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AMINOALCOHOL SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS von MÖNNING, Ursula, MÖWES, Manfred, HÄGEBARTH, Andrea, BÖMER, Ulf, SCOTT, William Johnston, LIU, Ningshu

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Combination of PI3K-inhibitors von Scholz, Arne, Hägebarth, Andrea, Liu, Ningshu

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COMBINATION OF PI3K-INHIBITORS von HÄGEBARTH Andrea, SCHOLZ Arne, LIU Ningshu

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