Systematic reanalysis of clinical exome data yields additional diagnoses: implications for providers von Wenger, Aaron M., Guturu, Harendra, Bernstein, Jonathan A., Bejerano, Gill

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M-CAP eliminates a majority of variants of uncertain significance in clinical exomes at high sensitivity von Jagadeesh, Karthik A, Wenger, Aaron M, Berger, Mark J, Guturu, Harendra, Stenson, Peter D, Cooper, David N, Bernstein, Jonathan A, Bejerano, Gill

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Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping von Suhre, Karsten, Venkataraman, Guhan Ram, Guturu, Harendra, Halama, Anna, Stephan, Nisha, Thareja, Gaurav, Sarwath, Hina, Motamedchaboki, Khatereh, Donovan, Margaret K. R., Siddiqui, Asim, Batzoglou, Serafim, Schmidt, Frank

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Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape von Camp, J Gray, Frank, Christopher L, Lickwar, Colin R, Guturu, Harendra, Rube, Tomas, Wenger, Aaron M, Chen, Jenny, Bejerano, Gill, Crawford, Gregory E, Rawls, John F

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Clustering of 770,000 genomes reveals post-colonial population structure of North America von Han, Eunjung, Carbonetto, Peter, Curtis, Ross E., Wang, Yong, Granka, Julie M., Byrnes, Jake, Noto, Keith, Kermany, Amir R., Myres, Natalie M., Barber, Mathew J., Rand, Kristin A., Song, Shiya, Roman, Theodore, Battat, Erin, Elyashiv, Eyal, Guturu, Harendra, Hong, Eurie L., Chahine, Kenneth G., Ball, Catherine A.

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A Scaled Proteomic Discovery Study for Prostate Cancer Diagnostic Markers Using ProteographTM and Trapped Ion Mobility Mass Spectrometry von Chang, Matthew E. K., Lange, Jane, Cartier, Jessie May, Moore, Travis W., Soriano, Sophia M., Albracht, Brenna, Krawitzky, Michael, Guturu, Harendra, Alavi, Amir, Stukalov, Alexey, Zhou, Xiaoyuan, Elgierari, Eltaher M., Chu, Jessica, Benz, Ryan, Cuevas, Juan C., Ferdosi, Shadi, Hornburg, Daniel, Farokhzad, Omid, Siddiqui, Asim, Batzoglou, Serafim, Leach, Robin J., Liss, Michael A., Kopp, Ryan P., Flory, Mark R.

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Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories von Guturu, Harendra, Chinchali, Sandeep, Clarke, Shoa L, Bejerano, Gill

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Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects von Roberts, Genevieve H. L., Partha, Raghavendran, Rhead, Brooke, Knight, Spencer C., Park, Danny S., Coignet, Marie V., Zhang, Miao, Berkowitz, Nathan, Turrisini, David A., Gaddis, Michael, McCurdy, Shannon R., Pavlovic, Milos, Ruiz, Luong, Sass, Chodon, Haug Baltzell, Asher K., Guturu, Harendra, Girshick, Ahna R., Ball, Catherine A., Hong, Eurie L., Rand, Kristin A.

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COVID-19 susceptibility and severity risks in a cross-sectional survey of over 500 000 US adults von Knight, Spencer C, McCurdy, Shannon R, Rhead, Brooke, Coignet, Marie V, Park, Danny S, Roberts, Genevieve H L, Berkowitz, Nathan D, Zhang, Miao, Turissini, David, Delgado, Karen, Pavlovic, Milos, Haug Baltzell, Asher K, Guturu, Harendra, Rand, Kristin A, Girshick, Ahna R, Hong, Eurie L, Ball, Catherine A, Banda, Yambazi, Bi, Ke, Burton, Robert, Champine, Marjan, Curtis, Ross, Drokhlyansky, Abby, Elrick, Ashley, Foo, Cat, Gaddis, Michael, Gu, Jialiang, Hateley, Shannon, Harris, Heather, King, Shea, Maldonado, Christine, McCartney-Melstad, Evan, McFarland, Alexandra, Miller, Patty, Nguyen, Luong, Noto, Keith, Pei, Jingwen, Petersen, Jenna, Pew, Scott, Sass, Chodon, Schraiber, Josh, Sedghifar, Alisa, Smelter, Andrey, South, Sarah, Starr, Barry, Vaughn, Cecily, Wang, Yong

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The enhancer landscape during early neocortical development reveals patterns of dense regulation and co-option von Wenger, Aaron M, Clarke, Shoa L, Notwell, James H, Chung, Tisha, Tuteja, Geetu, Guturu, Harendra, Schaar, Bruce T, Bejerano, Gill

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BioText Search Engine: beyond abstract search von Hearst, Marti A., Divoli, Anna, Guturu, Harendra, Ksikes, Alex, Nakov, Preslav, Wooldridge, Michael A., Ye, Jerry

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A first update on mapping the human genetic architecture of COVID-19 von Pathak, Gita A., Karjalainen, Juha, Stevens, Christine, Neale, Benjamin M., Daly, Mark, Ganna, Andrea, Andrews, Shea J., Kanai, Masahiro, Cordioli, Mattia, Polimanti, Renato, Harerimana, Nadia, Pirinen, Matti, Liao, Rachel G., Chwialkowska, Karolina, Trankiem, Amy, Balaconis, Mary K., Nguyen, Huy, Solomonson, Matthew, Veerapen, Kumar, Wolford, Brooke, Roberts, Genevieve, Park, Danny, Ball, Catherine A., Coignet, Marie, McCurdy, Shannon, Knight, Spencer, Partha, Raghavendran, Rhead, Brooke, Zhang, Miao, Berkowitz, Nathan, Gaddis, Michael, Noto, Keith, Ruiz, Luong, Pavlovic, Milos, Hong, Eurie L., Rand, Kristin, Girshick, Ahna, Guturu, Harendra, Baltzell, Asher Haug, Niemi, Mari E. K., Rahmouni, Souad, Guntz, Julien, Beguin, Yves, Pigazzini, Sara, Nkambule, Lindokuhle, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gilles, Guiot, Julien, Azarzar, Samira, Gofflot, Stéphanie, Claassen, Sabine, Malaise, Olivier, Huynen, Pascale, Meuris, Christelle, Thys, Marie, Jacques, Jessica, Léonard, Philippe, Frippiat, Frederic, Giot, Jean-Baptiste, Sauvage, Anne-Sophie, Frenckell, Christian Von, Belhaj, Yasmine, Lambermont, Bernard, Nakanishi, Tomoko, Morrison, David R., Mooser, Vincent, Richards, J. Brent, Butler-Laporte, Guillaume, Forgetta, Vincenzo, Li, Rui, Ghosh, Biswarup, Laurent, Laetitia, Belisle, Alexandre, Henry, Danielle, Abdullah, Tala, Adeleye, Olumide, Mamlouk, Noor, Kimchi, Nofar, Afrasiabi, Zaman, Rezk, Nardin, Vulesevic, Branka, Bouab, Meriem, Guzman, Charlotte, Petitjean, Louis, Tselios, Chris, Xue, Xiaoqing, Afilalo, Jonathan, Afilalo, Marc, Oliveira, Maureen, Brenner, Bluma, Brassard, Nathalie, Durand, Madeleine, Schurr, Erwin, Lepage, Pierre, Ragoussis, Jiannis, Auld, Daniel, Chassé, Michaël, Kaufmann, Daniel E.

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Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease von Horowitz, Julie E., Kosmicki, Jack A., Damask, Amy, Sharma, Deepika, Roberts, Genevieve H. L., Justice, Anne E., Banerjee, Nilanjana, Coignet, Marie V., Yadav, Ashish, Leader, Joseph B., Marcketta, Anthony, Park, Danny S., Lanche, Rouel, Maxwell, Evan, Knight, Spencer C., Bai, Xiaodong, Guturu, Harendra, Sun, Dylan, Baltzell, Asher, Kury, Fabricio S. P., Backman, Joshua D., Girshick, Ahna R., O’Dushlaine, Colm, McCurdy, Shannon R., Partha, Raghavendran, Mansfield, Adam J., Turissini, David A., Li, Alexander H., Zhang, Miao, Mbatchou, Joelle, Watanabe, Kyoko, Gurski, Lauren, McCarthy, Shane E., Kang, Hyun M., Dobbyn, Lee, Stahl, Eli, Verma, Anurag, Sirugo, Giorgio, Ritchie, Marylyn D., Jones, Marcus, Balasubramanian, Suganthi, Siminovitch, Katherine, Salerno, William J., Shuldiner, Alan R., Rader, Daniel J., Mirshahi, Tooraj, Locke, Adam E., Marchini, Jonathan, Overton, John D., Carey, David J., Habegger, Lukas, Cantor, Michael N., Rand, Kristin A., Hong, Eurie L., Reid, Jeffrey G., Ball, Catherine A., Baras, Aris, Abecasis, Gonçalo R., Ferreira, Manuel A. R.

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Independent erosion of conserved transcription factor binding sites points to shared hindlimb, vision and external testes loss in different mammals von Berger, Mark J, Wenger, Aaron M, Guturu, Harendra, Bejerano, Gill

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Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects von Roberts, Genevieve H. L., Partha, Raghavendran, Rhead, Brooke, Knight, Spencer C., Park, Danny S., Coignet, Marie V., Zhang, Miao, Berkowitz, Nathan, Turrisini, David A., Gaddis, Michael, McCurdy, Shannon R., Pavlovic, Milos, Ruiz, Luong, Sass, Chodon, Haug Baltzell, Asher K., Guturu, Harendra, Girshick, Ahna R., Ball, Catherine A., Hong, Eurie L., Rand, Kristin A.

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Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly von Alcantara, Diana, Timms, Andrew E, Gripp, Karen, Baker, Laura, Park, Kaylee, Collins, Sarah, Cheng, Chi, Stewart, Fiona, Mehta, Sarju G, Saggar, Anand, Sztriha, László, Zombor, Melinda, Caluseriu, Oana, Mesterman, Ronit, Van Allen, Margot I, Jacquinet, Adeline, Ygberg, Sofia, Bernstein, Jonathan A, Wenger, Aaron M, Guturu, Harendra, Bejerano, Gill, Gomez-Ospina, Natalia, Lehman, Anna, Alfei, Enrico, Pantaleoni, Chiara, Conti, Valerio, Guerrini, Renzo, Moog, Ute, Graham, Jr, John M, Hevner, Robert, Dobyns, William B, O'Driscoll, Mark, Mirzaa, Ghayda M

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Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development von Aguillon, Raphael, Madelaine, Romain, Aguirrebengoa, Marion, Guturu, Harendra, Link, Sandra, Dufourcq, Pascale, Lecaudey, Virginie, Bejerano, Gill, Blader, Patrick, Batut, Julie

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Computational methods to detect conserved non-genic elements in phylogenetically isolated genomes: application to zebrafish von Hiller, Michael, Agarwal, Saatvik, Notwell, James H, Parikh, Ravi, Guturu, Harendra, Wenger, Aaron M, Bejerano, Gill

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Phrank measures phenotype sets similarity to greatly improve Mendelian diagnostic disease prioritization von Jagadeesh, Karthik A., Birgmeier, Johannes, Guturu, Harendra, Deisseroth, Cole A., Wenger, Aaron M., Bernstein, Jonathan A., Bejerano, Gill

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Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements von Guturu, Harendra, Doxey, Andrew C., Wenger, Aaron M., Bejerano, Gill

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