G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers von Arang, Nadia, Gutkind, J. Silvio

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Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer von Ma, Shenghong, Tang, Tracy, Probst, Gary, Konradi, Andrei, Jin, Chunyu, Li, Fulong, Gutkind, J. Silvio, Fu, Xiang-Dong, Guan, Kun-Liang

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B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade von Kim, Sangwoo S, Shen, Sarek, Miyauchi, Sayuri, Sanders, P Dominick, Franiak-Pietryga, Ida, Mell, Loren, Gutkind, J Silvio, Cohen, Ezra E W, Califano, Joseph A, Sharabi, Andrew B

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mTOR co-targeting strategies for head and neck cancer therapy von Wang, Zhiyong, Valera, Juan Callejas, Zhao, Xuefeng, Chen, Qianming, Silvio Gutkind, J.

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The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma von Fukusumi, Takahito, Guo, Theresa W, Sakai, Akihiro, Ando, Mizuo, Ren, Shuling, Haft, Sunny, Liu, Chao, Amornphimoltham, Panomwat, Gutkind, J Silvio, Califano, Joseph A

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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry von Feng, Xiaodong, Degese, Maria Sol, Iglesias-Bartolome, Ramiro, Vaque, Jose P., Molinolo, Alfredo A., Rodrigues, Murilo, Zaidi, M. Raza, Ksander, Bruce R., Merlino, Glenn, Sodhi, Akrit, Chen, Qianming, Gutkind, J. Silvio

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Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas von Gilardi, Mara, Wang, Zhiyong, Proietto, Marco, Chillà, Anastasia, Calleja-Valera, Juan Luis, Goto, Yusuke, Vanoni, Marco, Janes, Matthew R, Mikulski, Zbigniew, Gualberto, Antonio, Molinolo, Alfredo A, Ferrara, Napoleone, Gutkind, J Silvio, Burrows, Francis

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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics von Miyauchi, Sayuri, Kim, Sangwoo S, Pang, John, Gold, Kathryn A, Gutkind, J Silvio, Califano, Joseph A, Mell, Loren K, Cohen, Ezra E W, Sharabi, Andrew B

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Arrestins as rheostats of GPCR signalling von Gutkind, J. Silvio, Kostenis, Evi

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G-protein-coupled receptors and cancer von Dorsam, Robert T., Gutkind, J. Silvio

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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4 von Wang, Zhiyong, Wu, Victoria H., Allevato, Michael M., Gilardi, Mara, He, Yudou, Luis Callejas-Valera, Juan, Vitale-Cross, Lynn, Martin, Daniel, Amornphimoltham, Panomwat, Mcdermott, James, Yung, Bryan S., Goto, Yusuke, Molinolo, Alfredo A., Sharabi, Andrew B., Cohen, Ezra E. W., Chen, Qianming, Lyons, J. Guy, Alexandrov, Ludmil B., Gutkind, J. Silvio

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Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer von Rusling, James F, Kumar, Challa V, Gutkind, J. Silvio, Patel, Vyomesh

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The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer von O'Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio

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Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy von Wu, Victoria, Yeerna, Huwate, Nohata, Nijiro, Chiou, Joshua, Harismendy, Olivier, Raimondi, Francesco, Inoue, Asuka, Russell, Robert B., Tamayo, Pablo, Gutkind, J. Silvio

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Assembly and activation of the Hippo signalome by FAT1 tumor suppressor von Martin, Daniel, Degese, Maria S., Vitale-Cross, Lynn, Iglesias-Bartolome, Ramiro, Valera, Juan Luis Callejas, Wang, Zhiyong, Feng, Xiaodong, Yeerna, Huwate, Vadmal, Vachan, Moroishi, Toshiro, Thorne, Rick F., Zaida, Moraima, Siegele, Bradford, Cheong, Sok C., Molinolo, Alfredo A., Samuels, Yardena, Tamayo, Pablo, Guan, Kun Liang, Lippman, Scott M., Lyons, J. Guy, Gutkind, J. Silvio

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mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis von Iglesias-Bartolome, Ramiro, Patel, Vyomesh, Cotrim, Ana, Leelahavanichkul, Kantima, Molinolo, Alfredo A., Mitchell, James B., Gutkind, J. Silvio

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mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging von Castilho, Rogerio M., Squarize, Cristiane H., Chodosh, Lewis A., Williams, Bart O., Gutkind, J. Silvio

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HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers von Ren, Shuling, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Tamayo, Pablo, Callejas-Valera, Juan Luis, Allevato, Mike, Gilardi, Mara, Santos, Jessica, Fukusumi, Takahito, Sakai, Akihiro, Ando, Mizuo, Sadat, Sayed, Liu, Chao, Xu, Guorong, Fisch, Kathleen M., Wang, Zhiyong, Molinolo, Alfredo A., Gutkind, J. Silvio, Ideker, Trey, Koch, Wayne M., Califano, Joseph A.

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Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum von Chikkaveeraiah, Bhaskara V., Mani, Vigneshwaran, Patel, Vyomesh, Gutkind, J. Silvio, Rusling, James F.

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Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets von Iglesias-Bartolome, Ramiro, Martin, Daniel, Gutkind, J Silvio

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