Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification von Munroe, Melissa E, Lu, Rufei, Zhao, Yan D, Fife, Dustin A, Robertson, Julie M, Guthridge, Joel M, Niewold, Timothy B, Tsokos, George C, Keith, Michael P, Harley, John B, James, Judith A

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Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks von Pelikan, Richard C., Kelly, Jennifer A., Fu, Yao, Lareau, Caleb A., Tessneer, Kandice L., Wiley, Graham B., Wiley, Mandi M., Glenn, Stuart B., Harley, John B., Guthridge, Joel M., James, Judith A., Aryee, Martin J., Montgomery, Courtney, Gaffney, Patrick M.

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Identification of unique microRNA signature associated with lupus nephritis von Te, Jeannie L, Dozmorov, Igor M, Guthridge, Joel M, Nguyen, Kim L, Cavett, Joshua W, Kelly, Jennifer A, Bruner, Gail R, Harley, John B, Ojwang, Joshua O

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Proinflammatory Adaptive Cytokine and Shed Tumor Necrosis Factor Receptor Levels Are Elevated Preceding Systemic Lupus Erythematosus Disease Flare von Munroe, Melissa E., Vista, Evan S., Guthridge, Joel M., Thompson, Linda F., Merrill, Joan T., James, Judith A.

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Unique Sjögren’s syndrome patient subsets defined by molecular features von James, Judith A, Guthridge, Joel M, Chen, Hua, Lu, Rufei, Bourn, Rebecka L, Bean, Krista, Munroe, Melissa E, Smith, Miles, Chakravarty, Eliza, Baer, Alan N, Noaiseh, Ghaith, Parke, Ann, Boyle, Karen, Keyes-Elstein, Lynette, Coca, Andreea, Utset, Tammy, Genovese, Mark C, Pascual, Virginia, Utz, Paul J, Holers, V. Michael, Deane, Kevin D, Sivils, Kathy L, Aberle, Teresa, Wallace, Daniel J, McNamara, James, Franchimont, Nathalie, St. Clair, E. William

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Epstein Barr Virus Interleukin 10 Suppresses Anti-inflammatory Phenotype in Human Monocytes von Jog, Neelakshi R, Chakravarty, Eliza F, Guthridge, Joel M, James, Judith A

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Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus von Shen, Nan, Fu, Qiong, Deng, Yun, Qian, Xiaoxia, Zhao, Jian, Kaufman, Kenneth M., Wu, Yee Ling, Yu, C. Yung, Tang, Yuanjia, Chen, Ji-Yih, Yang, Wanling, Wong, Maida, Kawasaki, Aya, Tsuchiya, Naoyuki, Sumida, Takayuki, Kawaguchi, Yasushi, Howe, Hwee Siew, Mok, Mo Yin, Bang, So-Young, Liu, Fei-Lan, Chang, Deh-Ming, Takasaki, Yoshinari, Hashimoto, Hiroshi, Harley, John B., Guthridge, Joel M., Grossman, Jennifer M., Cantor, Rita M., Song, Yeong Wook, Bae, Sang-Cheol, Chen, Shunle, Hahn, Bevra H., Lau, Yu Lung, Tsao, Betty P., Smith, Kenneth G. C.

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Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis von Saruhan-Direskeneli, Güher, Hughes, Travis, Aksu, Kenan, Keser, Gokhan, Coit, Patrick, Aydin, Sibel Z., Alibaz-Oner, Fatma, Kamalı, Sevil, Inanc, Murat, Carette, Simon, Hoffman, Gary S., Akar, Servet, Onen, Fatos, Akkoc, Nurullah, Khalidi, Nader A., Koening, Curry, Karadag, Omer, Kiraz, Sedat, Langford, Carol A., McAlear, Carol A., Ozbalkan, Zeynep, Ates, Askin, Karaaslan, Yasar, Maksimowicz-McKinnon, Kathleen, Monach, Paul A., Ozer, Hüseyin T., Seyahi, Emire, Fresko, Izzet, Cefle, Ayse, Seo, Philip, Warrington, Kenneth J., Ozturk, Mehmet A., Ytterberg, Steven R., Cobankara, Veli, Onat, A. Mesut, Guthridge, Joel M., James, Judith A., Tunc, Ercan, Duzgun, Nurşen, Bıcakcıgil, Muge, Yentür, Sibel P., Merkel, Peter A., Direskeneli, Haner, Sawalha, Amr H.

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Immune Response to  Enterococcus gallinarum in Lupus Patients Is Associated With a Subset of Lupus-Associated Autoantibodies von Bagavant, Harini, Araszkiewicz, Antonina M, Ingram, Jessica K, Cizio, Katarzyna, Merrill, Joan T, Arriens, Cristina, Guthridge, Joel M, James, Judith A, Deshmukh, Umesh S

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Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype von Jog, Neelakshi R, Wagner, Catriona A, Aberle, Teresa, Chakravarty, Eliza F, Arriens, Cristina, Guthridge, Joel M, James, Judith A

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Vitamin d deficiency in a multiethnic healthy control cohort and altered immune response in vitamin D deficient European-American healthy controls von Ritterhouse, Lauren L, Lu, Rufei, Shah, Hemangi B, Robertson, Julie M, Fife, Dustin A, Maecker, Holden T, Du, Hongwu, Fathman, Charles G, Chakravarty, Eliza F, Scofield, R Hal, Kamen, Diane L, Guthridge, Joel M, James, Judith A

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Pathways of impending disease flare in African-American systemic lupus erythematosus patients von Munroe, Melissa E, Vista, Evan S, Merrill, Joan T, Guthridge, Joel M, Roberts, Virginia C, James, Judith A

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Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study von Guthridge, Joel M., Lu, Rufei, Tran, Ly Thi-Hai, Arriens, Cristina, Aberle, Teresa, Kamp, Stan, Munroe, Melissa E., Dominguez, Nicolas, Gross, Timothy, DeJager, Wade, Macwana, Susan R., Bourn, Rebecka L., Apel, Stephen, Thanou, Aikaterini, Chen, Hua, Chakravarty, Eliza F., Merrill, Joan T., James, Judith A.

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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus von Raj, Prithvi, Song, Ran, Zhu, Honglin, Riediger, Linley, Jun, Dong-Jae, Liang, Chaoying, Arana, Carlos, Zhang, Bo, Gao, Yajing, Wakeland, Benjamin E, Dozmorov, Igor, Zhou, Jinchun, Kelly, Jennifer A, Lauwerys, Bernard R, Guthridge, Joel M, Olsen, Nancy J, Nath, Swapan K, Pasare, Chandrashekhar, van Oers, Nicolai, Gilkeson, Gary, Tsao, Betty P, Gaffney, Patrick M, Gregersen, Peter K, James, Judith A, Zuo, Xiaoxia, Karp, David R, Li, Quan-Zhen, Wakeland, Edward K

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Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus... von Wood, Rebecca A., Guthridge, Lauren, Thurmond, Emma, Guthridge, Carla J., Kheir, Joseph M., Bourn, Rebecka L., Wagner, Catriona A., Chen, Hua, DeJager, Wade, Macwana, Susan R., Kamp, Stan, Lu, Rufei, Arriens, Cristina, Chakravarty, Eliza F., Thanou, Aikaterini, Merrill, Joan T., Guthridge, Joel M., James, Judith A.

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The promise of precision medicine in rheumatology von Guthridge, Joel M., Wagner, Catriona A., James, Judith A.

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Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis von Munroe, Melissa E, Pezant, Nathan, Brown, Michael A, Fife, Dustin A, Guthridge, Joel M, Kelly, Jennifer A, Wiley, Graham, Gaffney, Patrick M, James, Judith A, Montgomery, Courtney G

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Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus von Vanderlinden, Lauren A, Bemis, Elizabeth A, Seifert, Jennifer, Guthridge, Joel M, Young, Kendra A, Demoruelle, Mary Kristen, Feser, Marie, DeJager, Wade, Macwana, Susan, Mikuls, Ted R, O'Dell, James R, Weisman, Michael H, Buckner, Jane, Keating, Richard M, Gaffney, Patrick M, Kelly, Jennifer A, Langefeld, Carl D, Deane, Kevin D, James, Judith A, Holers, Vernon Michael, Norris, Jill M

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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically... von Munroe, Melissa E, Young, Kendra A, Guthridge, Joel M, Kamen, Diane L, Gilkeson, Gary S, Weisman, Michael H, Ishimori, Mariko L, Wallace, Daniel J, Karp, David R, Harley, John B, Norris, Jill M, James, Judith A

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Complement C3 activation is required for antiphospholipid antibody-induced fetal loss von Holers, V Michael, Girardi, Guillermina, Mo, Lian, Guthridge, Joel M, Molina, Hector, Pierangeli, Silvia S, Espinola, Ricardo, Xiaowei, Liu E, Mao, Dailing, Vialpando, Christopher G, Salmon, Jane E

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