Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination von Gustafsson, Nina M. S., Färnegårdh, Katarina, Bonagas, Nadilly, Ninou, Anna Huguet, Groth, Petra, Wiita, Elisee, Jönsson, Mattias, Hallberg, Kenth, Lehto, Jemina, Pennisi, Rosa, Martinsson, Jessica, Norström, Carina, Hollers, Jessica, Schultz, Johan, Andersson, Martin, Markova, Natalia, Marttila, Petra, Kim, Baek, Norin, Martin, Olin, Thomas, Helleday, Thomas

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Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor von Gustafsson, Robert, Jemth, Ann-Sofie, Gustafsson, Nina M S, Färnegårdh, Katarina, Loseva, Olga, Wiita, Elisée, Bonagas, Nadilly, Dahllund, Leif, Llona-Minguez, Sabin, Häggblad, Maria, Henriksson, Martin, Andersson, Yasmin, Homan, Evert, Helleday, Thomas, Stenmark, Pål

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The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells von Corvaisier, Matthieu, Zhou, Jingkai, Malycheva, Darina, Cornella, Nicola, Chioureas, Dimitrios, Gustafsson, Nina M. S., Rosselló, Catalina Ana, Ayora, Silvia, Li, Tongbin, Ekström-Holka, Kristina, Jirström, Karin, Lindström, Lisa, Alvarado-Kristensson, Maria

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Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum von Lehto, Jemina, Huguet Ninou, Anna, Chioureas, Dimitrios, Jonkers, Jos, Gustafsson, Nina M S

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress von Bonagas, Nadilly, Gustafsson, Nina M S, Henriksson, Martin, Marttila, Petra, Gustafsson, Robert, Wiita, Elisée, Borhade, Sanjay, Green, Alanna C, Vallin, Karl S A, Sarno, Antonio, Svensson, Richard, Göktürk, Camilla, Pham, Therese, Jemth, Ann-Sofie, Loseva, Olga, Cookson, Victoria, Kiweler, Nicole, Sandberg, Lars, Rasti, Azita, Unterlass, Judith E, Haraldsson, Martin, Andersson, Yasmin, Scaletti, Emma R, Bengtsson, Christoffer, Paulin, Cynthia B J, Sanjiv, Kumar, Abdurakhmanov, Eldar, Pudelko, Linda, Kunz, Ben, Desroses, Matthieu, Iliev, Petar, Färnegårdh, Katarina, Krämer, Andreas, Garg, Neeraj, Michel, Maurice, Häggblad, Sara, Jarvius, Malin, Kalderén, Christina, Jensen, Amanda Bögedahl, Almlöf, Ingrid, Karsten, Stella, Zhang, Si Min, Häggblad, Maria, Eriksson, Anders, Liu, Jianping, Glinghammar, Björn, Nekhotiaeva, Natalia, Klingegård, Fredrik, Koolmeister, Tobias, Martens, Ulf, Llona-Minguez, Sabin, Moulson, Ruth, Nordström, Helena, Parrow, Vendela, Dahllund, Leif, Sjöberg, Birger, Vargas, Irene L, Vo, Duy Duc, Wannberg, Johan, Knapp, Stefan, Krokan, Hans E, Arvidsson, Per I, Scobie, Martin, Meiser, Johannes, Stenmark, Pål, Berglund, Ulrika Warpman, Homan, Evert J, Helleday, Thomas

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Inactivation of Liver X Receptor β Leads to Adult-Onset Motor Neuron Degeneration in Male Mice von Andersson, Sandra, Gustafsson, Nina, Warner, Margaret, Gustafsson, Jan-Åke

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Small-molecule inhibitors of human mitochondrial DNA transcription von Bonekamp, Nina A., Peter, Bradley, Hillen, Hauke S., Felser, Andrea, Bergbrede, Tim, Choidas, Axel, Horn, Moritz, Unger, Anke, Di Lucrezia, Raffaella, Atanassov, Ilian, Li, Xinping, Koch, Uwe, Menninger, Sascha, Boros, Joanna, Habenberger, Peter, Giavalisco, Patrick, Cramer, Patrick, Denzel, Martin S., Nussbaumer, Peter, Klebl, Bert, Falkenberg, Maria, Gustafsson, Claes M., Larsson, Nils-Göran

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Massive remobilization of permafrost carbon during post-glacial warming von Tesi, T., Muschitiello, F., Smittenberg, R. H., Jakobsson, M., Vonk, J. E., Hill, P., Andersson, A., Kirchner, N., Noormets, R., Dudarev, O., Semiletov, I., Gustafsson, Ö

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Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer von Nilsson, Roland, Jain, Mohit, Madhusudhan, Nikhil, Sheppard, Nina Gustafsson, Strittmatter, Laura, Kampf, Caroline, Huang, Jenny, Asplund, Anna, Mootha, Vamsi K.

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The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation von Gustafsson Sheppard, Nina, Jarl, Lisa, Mahadessian, Diana, Strittmatter, Laura, Schmidt, Angelika, Madhusudan, Nikhil, Tegnér, Jesper, Lundberg, Emma K., Asplund, Anna, Jain, Mohit, Nilsson, Roland

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Bridging the gender gap: Insights from a contemporary analysis of sex-related differences in the treatment and outcomes of patients with acute coronary syndromes von Poon, Stephanie, MD, MSc, Goodman, Shaun G., MD, MSc, Yan, Raymond T., MD, Bugiardini, Raffaele, MD, Bierman, Arlene S., MD, MSc, Eagle, Kim A., MD, Johnston, Nina, MD, Huynh, Thao, MD, MSc, Grondin, Francois R., MD, Schenck-Gustafsson, Karin, MD, PhD, Yan, Andrew T., MD

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Estrogen Receptors: How Do They Signal and What Are Their Targets von Heldring, Nina, Pike, Ashley, Andersson, Sandra, Matthews, Jason, Cheng, Guojun, Hartman, Johan, Tujague, Michel, Strom, Anders, Treuter, Eckardt, Warner, Margaret, Gustafsson, Jan-Ake

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Sex Differences in Cardiovascular Disease – Impact on Care and Outcomes von Humphries, K.H, Izadnegadar, M, Sedlak, T, Saw, J, Johnston, N, Schenck-Gustafsson, K, Shah, R.U, Regitz-Zagrosek, V, Grewal, J, Vaccarino, V, Wei, J, Bairey Merz, C.N

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Effect of Gender on Patients With ST-Elevation and Non-ST-Elevation Myocardial Infarction Without Obstructive Coronary Artery Disease von Johnston, Nina, MD, PhD, Jönelid, Birgitta, MD, Christersson, Christina, MD, PhD, Kero, Tanja, MD, Renlund, Henrik, PhD, Schenck-Gustafsson, Karin, MD, PhD, Lagerqvist, Bo, MD, PhD

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E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis von Ehrlund, Anna, Anthonisen, Elin Holter, Gustafsson, Nina, Venteclef, Nicolas, Robertson Remen, Kirsten, Damdimopoulos, Anastasios E., Galeeva, Anastasia, Pelto-Huikko, Markku, Lalli, Enzo, Steffensen, Knut R., Gustafsson, Jan-Åke, Treuter, Eckardt

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Auranofin and N-heterocyclic carbene gold-analogs are potent inhibitors of the bacteria Helicobacter pylori von Owings, Joshua P., McNair, Nina N., Mui, Yiu Fung, Gustafsson, Tomas N., Holmgren, Arne, Contel, Maria, Goldberg, Joanna B., Mead, Jan R.

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POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA von Kühl, Inge, Miranda, Maria, Posse, Viktor, Milenkovic, Dusanka, Mourier, Arnaud, Siira, Stefan J, Bonekamp, Nina A, Neumann, Ulla, Filipovska, Aleksandra, Polosa, Paola Loguercio, Gustafsson, Claes M, Larsson, Nils-Göran

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Liver X receptors are required for thymic resilience and T cell output von Chan, Christopher T, Fenn, Ashley M, Harder, Nina K, Mindur, John E, McAlpine, Cameron S, Patel, Jyoti, Valet, Colin, Rattik, Sara, Iwamoto, Yoshiko, He, Shun, Anzai, Atsushi, Kahles, Florian, Poller, Wolfram C, Janssen, Henrike, Wong, Lai Ping, Fernandez-Hernando, Carlos, Koolbergen, David R, van der Laan, Anja M, Yvan-Charvet, Laurent, Sadreyev, Ruslan I, Nahrendorf, Matthias, Westerterp, Marit, Tall, Alan R, Gustafsson, Jan-Ake, Swirski, Filip K

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Cost Burden of Crohn’s Disease and Ulcerative Colitis in the 10-Year Period Before Diagnosis—A Danish Register-Based Study From 2003–2015 von Vadstrup, Kasper, Alulis, Sarah, Borsi, Andras, Gustafsson, Nina, Nielsen, Agnete, Wennerström, E Christina M, Jørgensen, Tine Rikke, Qvist, Niels, Munkholm, Pia

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Obesity and Disturbed Lipoprotein Profile in Estrogen Receptor-α-Deficient Male Mice von Ohlsson, Claes, Hellberg, Nina, Parini, Paolo, Vidal, Olle, Bohlooly, Mohammed, Rudling, Mats, Lindberg, Marie K., Warner, Margaret, Angelin, Bo, Gustafsson, Jan-Åke

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