Lipids as Regulators of Cellular Senescence von Hamsanathan, Shruthi, Gurkar, Aditi U

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Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice von Yousefzadeh, Matthew J., Zhao, Jing, Bukata, Christina, Wade, Erin A., McGowan, Sara J., Angelini, Luise A., Bank, Michael P., Gurkar, Aditi U., McGuckian, Collin A., Calubag, Mariah F., Kato, Jonathan I., Burd, Christin E., Robbins, Paul D., Niedernhofer, Laura J.

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Selective killing of cancer cells by a small molecule targeting the stress response to ROS von Raj, Lakshmi, Ide, Takao, Gurkar, Aditi U., Foley, Michael, Schenone, Monica, Li, Xiaoyu, Tolliday, Nicola J., Golub, Todd R., Carr, Steven A., Shamji, Alykhan F., Stern, Andrew M., Mandinova, Anna, Schreiber, Stuart L., Lee, Sam W.

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DNA damage-induced stalling of transcription drives aging through gene expression imbalance von Sims, Austin A., Gurkar, Aditi U.

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The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs von Zhu, Yi, Tchkonia, Tamara, Pirtskhalava, Tamar, Gower, Adam C., Ding, Husheng, Giorgadze, Nino, Palmer, Allyson K., Ikeno, Yuji, Hubbard, Gene B., Lenburg, Marc, O'Hara, Steven P., LaRusso, Nicholas F., Miller, Jordan D., Roos, Carolyn M., Verzosa, Grace C., LeBrasseur, Nathan K., Wren, Jonathan D., Farr, Joshua N., Khosla, Sundeep, Stout, Michael B., McGowan, Sara J., Fuhrmann‐Stroissnigg, Heike, Gurkar, Aditi U., Zhao, Jing, Colangelo, Debora, Dorronsoro, Akaitz, Ling, Yuan Yuan, Barghouthy, Amira S., Navarro, Diana C., Sano, Tokio, Robbins, Paul D., Niedernhofer, Laura J., Kirkland, James L.

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Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress von Gurkar, Aditi U., Chu, Kiki, Raj, Lakshmi, Bouley, Richard, Lee, Seung-Hwan, Kim, Young-Bum, Dunn, Sandra E., Mandinova, Anna, Lee, Sam W.

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Analysis of representative mutants for key DNA repair pathways on healthspan in Caenorhabditis elegans von Marchal, Lucile, Hamsanathan, Shruthi, Karthikappallil, Roshan, Han, Suhao, Shinglot, Himaly, Gurkar, Aditi U.

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Comparison of mice with accelerated aging caused by distinct mechanisms von Gurkar, Aditi U., Niedernhofer, Laura J.

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Frataxin deficiency promotes endothelial senescence in pulmonary hypertension von Culley, Miranda K., Zhao, Jingsi, Tai, Yi Yin, Tang, Ying, Perk, Dror, Negi, Vinny, Yu, Qiujun, Woodcock, Chen-Shan C., Handen, Adam, Speyer, Gil, Kim, Seungchan, Lai, Yen-Chun, Satoh, Taijyu, Watson, Annie M. M., Al Aaraj, Yassmin, Sembrat, John, Rojas, Mauricio, Goncharov, Dmitry, Goncharova, Elena A., Khan, Omar F., Anderson, Daniel G., Dahlman, James E., Gurkar, Aditi U., Lafyatis, Robert, Fayyaz, Ahmed U., Redfield, Margaret M., Gladwin, Mark T., Rabinovitch, Marlene, Gu, Mingxia, Bertero, Thomas, Chan, Stephen Y.

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ATM is a key driver of NF-kappa B-dependent DNA-damage-induced senescence, stem cell dysfunction and aging von Zhao, Jing, Zhang, Lei, Lu, Aiping, Han, Yingchao, Colangelo, Debora, Bukata, Christina, Scibetta, Alex, Yousefzadeh, Matthew J., Li, Xuesen, Gurkar, Aditi U., McGowan, Sara J., Angelini, Luise, O'Kelly, Ryan, Li, Hongshuai, Corbo, Lana, Sano, Tokio, Nick, Heather, Pola, Enrico, Pilla, Smitha P. S., Ladiges, Warren C., Nam Vo, Huard, Johnny, Niedernhofer, Laura J., Robbins, Paul D.

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A Chemoptogenetic Tool for Spatiotemporal Induction of Oxidative DNA Lesions In Vivo von Han, Suhao, Sims, Austin, Aceto, Anthony, Schmidt, Brigitte F, Bruchez, Marcel P, Gurkar, Aditi U

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Synergistic treatment of TS von Gurkar, Aditi U, Finkel, Toren

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An alternatively spliced, non-signaling insulin receptor modulates insulin sensitivity via insulin peptide sequestration in C. elegans von Martinez, Bryan A., Rodrigues, Pedro Reis, Medina, Ricardo M. Nunez, Mondal, Prosenjit, Harrison, Neale J., Lone, Museer A., Webster, Amanda, Gurkar, Aditi U., Grill, Brock, Gill, Matthew S.

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Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy von Henpita, Chathurika, Vyas, Rajesh, Healy, Chastity L., Kieu, Tra L., Gurkar, Aditi U., Yousefzadeh, Matthew J., Cui, Yuxiang, Lu, Aiping, Angelini, Luise A., O'Kelly, Ryan D., McGowan, Sara J., Chandrasekhar, Sanjay, Vanderpool, Rebecca R., Hennessy‐Wack, Danielle, Ross, Mark A., Bachman, Timothy N., McTiernan, Charles, Pillai, Smitha P. S., Ladiges, Warren, Lavasani, Mitra, Huard, Johnny, Beer‐Stolz, Donna, St. Croix, Claudette M., Watkins, Simon C., Robbins, Paul D., Mora, Ana L., Kelley, Eric E., Wang, Yinsheng, O'Connell, Timothy D., Niedernhofer, Laura J.

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Spatial mapping of cellular senescence: emerging challenges and opportunities von Gurkar, Aditi U, Gerencser, Akos A, Mora, Ana L, Nelson, Andrew C, Zhang, Anru R, Lagnado, Anthony B, Enninful, Archibald, Benz, Christopher, Furman, David, Beaulieu, Delphine, Jurk, Diana, Thompson, Elizabeth L, Wu, Fei, Rodriguez, Fernanda, Barthel, Grant, Chen, Hao, Phatnani, Hemali, Heckenbach, Indra, Chuang, Jeffrey H, Horrell, Jeremy, Petrescu, Joana, Alder, Jonathan K, Lee, Jun Hee, Niedernhofer, Laura J, Kumar, Manoj, Königshoff, Melanie, Bueno, Marta, Sokka, Miiko, Scheibye-Knudsen, Morten, Neretti, Nicola, Eickelberg, Oliver, Adams, Peter D, Hu, Qianjiang, Zhu, Quan, Porritt, Rebecca A, Dong, Runze, Peters, Samuel, Victorelli, Stella, Pengo, Thomas, Khaliullin, Timur, Suryadevara, Vidyani, Fu, Xiaonan, Bar-Joseph, Ziv, Ji, Zhicheng, Passos, João F

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Integrated -omics approach reveals persistent DNA damage rewires lipid metabolism and histone hyperacetylation via MYS-1/Tip60 von Hamsanathan, Shruthi, Anthonymuthu, Tamil, Han, Suhao, Shinglot, Himaly, Siefken, Ella, Sims, Austin, Sen, Payel, Pepper, Hannah L, Snyder, Nathaniel W, Bayir, Hulya, Kagan, Valerian, Gurkar, Aditi U

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Quantitative Analysis of Cellular Senescence in Culture and In Vivo von Zhao, Jing, Fuhrmann‐Stroissnigg, Heike, Gurkar, Aditi U., Flores, Rafael R., Dorronsoro, Akaitz, Stolz, Donna B., St. Croix, Claudette M., Niedernhofer, Laura J., Robbins, Paul D.

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Correction: Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS von Raj, Lakshmi, Ide, Takao, Gurkar, Aditi U., Foley, Michael, Schenone, Monica, Li, Xiaoyu, Tolliday, Nicola J., Golub, Todd R., Carr, Steven A., Shamji, Alykhan F., Stern, Andrew M., Mandinova, Anna, Schreiber, Stuart L., Lee, Sam W.

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Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis von Hiraki, Masatsugu, Hwang, So-Young, Cao, Shugeng, Ramadhar, Timothy R., Byun, Sanguine, Yoon, Kyoung Wan, Lee, Jung Hyun, Chu, Kiki, Gurkar, Aditi U., Kolev, Vihren, Zhang, Jianming, Namba, Takushi, Murphy, Maureen E., Newman, David J., Mandinova, Anna, Clardy, Jon, Lee, Sam W.

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Methods to Quantify the NF-κB Pathway During Senescence von Zhang, Lei, Zhao, Jing, Gurkar, Aditi, Niedernhofer, Laura J., Robbins, Paul D.

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