Re-evaluating the role of Tao1 in the spindle checkpoint von Westhorpe, Frederick G, Diez, Maria A, Gurden, Mark D. J, Tighe, Anthony, Taylor, Stephen S

Volltext

Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F von Gurden, Mark D.J, Holland, Andrew J, van Zon, Wouter, Tighe, Anthony, Vergnolle, Mailys A, Andres, Douglas A, Spielmann, H. Peter, Malumbres, Marcos, Wolthuis, Rob M.F, Cleveland, Don W, Taylor, Stephen S

Volltext

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer von Bajrami, Ilirjana, Marlow, Rebecca, van de Ven, Marieke, Brough, Rachel, Pemberton, Helen N, Frankum, Jessica, Song, Feifei, Rafiq, Rumana, Konde, Asha, Krastev, Dragomir B, Menon, Malini, Campbell, James, Gulati, Aditi, Kumar, Rahul, Pettitt, Stephen J, Gurden, Mark D, Cardenosa, Marta Llorca, Chong, Irene, Gazinska, Patrycja, Wallberg, Fredrik, Sawyer, Elinor J, Martin, Lesley-Ann, Dowsett, Mitch, Linardopoulos, Spiros, Natrajan, Rachael, Ryan, Colm J, Derksen, Patrick W B, Jonkers, Jos, Tutt, Andrew N J, Ashworth, Alan, Lord, Christopher J

Volltext

High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers von Anderhub, Simon J, Mak, Grace Wing-Yan, Gurden, Mark D, Faisal, Amir, Drosopoulos, Konstantinos, Walsh, Katie, Woodward, Hannah L, Innocenti, Paolo, Westwood, Isaac M, Naud, Sébastien, Hayes, Angela, Theofani, Efthymia, Filosto, Simone, Saville, Harry, Burke, Rosemary, van Montfort, Rob L M, Raynaud, Florence I, Blagg, Julian, Hoelder, Swen, Eccles, Suzanne A, Linardopoulos, Spiros

Volltext

Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis von Gurden, Mark D, Anderhub, Simon J, Faisal, Amir, Linardopoulos, Spiros

Volltext

Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance von Gurden, Mark D, Westwood, Isaac M, Faisal, Amir, Naud, Sébastien, Cheung, Kwai-Ming J, McAndrew, Craig, Wood, Amy, Schmitt, Jessica, Boxall, Kathy, Mak, Grace, Workman, Paul, Burke, Rosemary, Hoelder, Swen, Blagg, Julian, Van Montfort, Rob L M, Linardopoulos, Spiros

Volltext

Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy von Faisal, Amir, Mak, Grace W Y, Gurden, Mark D, Xavier, Cristina P R, Anderhub, Simon J, Innocenti, Paolo, Westwood, Isaac M, Naud, Sébastien, Hayes, Angela, Box, Gary, Valenti, Melanie R, De Haven Brandon, Alexis K, O'Fee, Lisa, Schmitt, Jessica, Woodward, Hannah L, Burke, Rosemary, vanMontfort, Rob L M, Blagg, Julian, Raynaud, Florence I, Eccles, Suzanne A, Hoelder, Swen, Linardopoulos, Spiros

Volltext

Abstract 2986: E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer von Bajrami, Ilirjana, Marlow, Rebecca, Ven, Marieke van de, Brough, Rachel, Pemberton, Helen N., Frankum, Jessica, Song, Fei Fei, Rafiq, Rumana, Konde, Asha, Menon, Malini, Campbell, James, Gulati, Aditi, Kumar, Rahul, Pettitt, Stephen J., Gurden, Mark D., Cardenosa, Marta Llorca, Chong, Irene, Gazinska, Patrycja, Wallberg, Fredrik, Sawyer, Elinor J., Martin, Lesley-Ann, Dowsett, Mitch, Linardopoulos, Spiros, Ryan, Colm, Derksen, Patrick W., Jonkers, Jos, Tutt, Andrew N.J., Ashworth, Alan, Lord, Christopher J.

Volltext