Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach von Beswick, Paul J., Blackaby, Andrew P., Bountra, Chas, Brown, Terry, Browning, Kerry, Campbell, Ian B., Corfield, John, Gleave, Robert J., Guntrip, Steve B., Hall, Richard M., Hindley, Sean, Lambeth, Paul F., Lucas, Fiona, Mathews, Neil, Naylor, Alan, Player, Hazel, Price, Helen S., Sidebottom, Phillip J., Taylor, Nicholas L., Webb, Graham, Wiseman, Joanne

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