Multiple myeloma: the (r)evolution of current therapy and a glance into future von Gulla, Annamaria, Anderson, Kenneth C

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CRISPR Interference (CRISPRi) and CRISPR Activation (CRISPRa) to Explore the Oncogenic lncRNA Network von Morelli, Eugenio, Gulla’, Annamaria, Amodio, Nicola, Taiana, Elisa, Neri, Antonino, Fulciniti, Mariateresa, Munshi, Nikhil C.

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Mir-34: A New Weapon Against Cancer? von Misso, Gabriella, Di Martino, Maria Teresa, De Rosa, Giuseppe, Farooqi, Ammad Ahmad, Lombardi, Angela, Campani, Virginia, Zarone, Mayra Rachele, Gullà, Annamaria, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Caraglia, Michele

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Harnessing the Immune System Against Multiple Myeloma: Challenges and Opportunities von Yamamoto, Leona, Amodio, Nicola, Gulla, Annamaria, Anderson, Kenneth Carl

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A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells von Gullà, Annamaria, Di Martino, Maria Teresa, Gallo Cantafio, Maria Eugenia, Morelli, Eugenio, Amodio, Nicola, Botta, Cirino, Pitari, Maria Rita, Lio, Santo Giovanni, Britti, Domenico, Stamato, Maria Angelica, Hideshima, Teru, Munshi, Nikhil C, Anderson, Kenneth C, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts von Pitari, Maria Rita, Rossi, Marco, Amodio, Nicola, Botta, Cirino, Morelli, Eugenio, Federico, Cinzia, Gullà, Annamaria, Caracciolo, Daniele, Di Martino, Maria Teresa, Arbitrio, Mariamena, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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Targeting miR-21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth von LEONE, Emanuela, MORELLI, Eugenio, ANDERSON, Kenneth C, TAGLIAFERRI, Pierosandro, TASSONE, Pierfrancesco, DI MARTINO, Maria T, AMODIO, Nicola, FORESTA, Umberto, GULLA, Annamaria, ROSSI, Marco, NERI, Antonino, GIORDANO, Antonio, MUNSHI, Nikhil C

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In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma von Di Martino, Maria Teresa, Campani, Virginia, Misso, Gabriella, Gallo Cantafio, Maria Eugenia, Gullà, Annamaria, Foresta, Umberto, Guzzi, Pietro Hiram, Castellano, Maria, Grimaldi, Anna, Gigantino, Vincenzo, Franco, Renato, Lusa, Sara, Cannataro, Mario, Tagliaferri, Pierosandro, De Rosa, Giuseppe, Tassone, Pierfrancesco, Caraglia, Michele

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Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92 von Morelli, Eugenio, Biamonte, Lavinia, Federico, Cinzia, Amodio, Nicola, Di Martino, Maria Teresa, Gallo Cantafio, Maria Eugenia, Manzoni, Martina, Scionti, Francesca, Samur, Mehmet Kemal, Gullà, Annamaria, Stamato, Maria Angelica, Pitari, Maria Rita, Caracciolo, Daniele, Sesti, Settimio, Frandsen, Niels M., Rossi, Marco, Neri, Antonino, Fulciniti, Mariateresa, Munshi, Nikhil C., Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells von Di Martino, Maria Teresa, Gullà, Annamaria, Gallo Cantafio, Maria Eugenia, Altomare, Emanuela, Amodio, Nicola, Leone, Emanuela, Morelli, Eugenio, Lio, Santo Giovanni, Caracciolo, Daniele, Rossi, Marco, Frandsen, Niels M, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma von Liu, Jiye, Xing, Lijie, Li, Jiang, Wen, Kenneth, Liu, Ning, Liu, Yuntong, Wu, Gongwei, Wang, Su, Ogiya, Daisuke, Song, Tian-Yu, Kurata, Keiji, Penailillo, Johany, Morelli, Eugenio, Wang, Tingjian, Hong, Xiaoning, Gulla, Annamaria, Tai, Yu-Tzu, Munshi, Nikhil, Richardson, Paul, Carrasco, Ruben, Hideshima, Teru, Anderson, Kenneth C.

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Single-Nuclei Transcriptome Profiling Reveals Intra-Tumoral Heterogeneity and Characterizes Tumor Microenvironment Architecture in a Murine Melanoma Model von Parab, Sushant, Sarlo, Valery, Capellero, Sonia, Palmiotto, Luca, Bartolini, Alice, Cantarella, Daniela, Turi, Marcello, Gullà, Annamaria, Grassi, Elena, Lazzari, Chiara, Rubatto, Marco, Gregorc, Vanesa, Carnevale-Schianca, Fabrizio, Olivero, Martina, Bussolino, Federico, Comunanza, Valentina

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Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence von DI MARTINO, Maria T, LEONE, Emanuela, TOMAINO, Vera, ROSSI, Marco, NEGRINI, Massimo, FERRARINI, Manlio, CARAGLIA, Michele, SHAMMAS, Masood A, MUNSHI, Nikhil C, ANDERSON, Kenneth C, NERI, Antonino, TAGLIAFERRI, Pierosandro, AMODIO, Nicola, TASSONE, Pierfrancesco, FORESTA, Umberto, LIONETTI, Marta, PITARI, Maria R, GALLO CANTAFIO, Maria E, GULLA, Annamaria, CONFORTI, Francesco, MORELLI, Eugenio

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Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma von Samur, Mehmet Kemal, Minvielle, Stephane, Gulla, Annamaria, Fulciniti, Mariateresa, Cleynen, Alice, Aktas Samur, Anil, Szalat, Raphael, Shammas, Masood, Magrangeas, Florence, Tai, Yu-Tzu, Auclair, Daniel, Keats, Jonathan, Richardson, Paul, Attal, Michel, Moreau, Philippe, Anderson, Kenneth C., Parmigiani, Giovanni, Avet-Loiseau, Hervé, Munshi, Nikhil C.

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A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth von Morelli, Eugenio, Fulciniti, Mariateresa, Samur, Mehmet K., Ribeiro, Caroline F., Wert-Lamas, Leon, Henninger, Jon E., Gullà, Annamaria, Aktas-Samur, Anil, Todoerti, Katia, Talluri, Srikanth, Park, Woojun D., Federico, Cinzia, Scionti, Francesca, Amodio, Nicola, Bianchi, Giada, Johnstone, Megan, Liu, Na, Gramegna, Doriana, Maisano, Domenico, Russo, Nicola A., Lin, Charles, Tai, Yu-Tzu, Neri, Antonino, Chauhan, Dharminder, Hideshima, Teru, Shammas, Masood A., Tassone, Pierfrancesco, Gryaznov, Sergei, Young, Richard A., Anderson, Kenneth C., Novina, Carl D., Loda, Massimo, Munshi, Nikhil C.

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BCMA-targeted bortezomib nanotherapy improves therapeutic efficacy, overcomes resistance, and modulates the immune microenvironment in multiple myeloma von Dutta, Debasmita, Liu, Jiye, Wen, Kenneth, Kurata, Keiji, Fulciniti, Mariateresa, Gulla, Annamaria, Hideshima, Teru, Anderson, Kenneth C.

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In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma von Di Martino, Maria Teresa, Gullà, Annamaria, Cantafio, Maria Eugenia Gallo, Lionetti, Marta, Leone, Emanuela, Amodio, Nicola, Guzzi, Pietro Hiram, Foresta, Umberto, Conforti, Francesco, Cannataro, Mario, Neri, Antonino, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets... von Turi, Marcello, Anilkumar Sithara, Anjana, Hofmanová, Lucie, Žihala, David, Radhakrishnan, Dhwani, Vdovin, Alexander, Knápková, Sofija, Ševčíková, Tereza, Chyra, Zuzana, Jelínek, Tomáš, Šimíček, Michal, Gullà, Annamaria, Anderson, Kenneth Carl, Hájek, Roman, Hrdinka, Matouš

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Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity von Raimondi, Lavinia, Amodio, Nicola, Di Martino, Maria Teresa, Altomare, Emanuela, Leotta, Marzia, Caracciolo, Daniele, Gullà, Annamaria, Neri, Antonino, Taverna, Simona, D'Aquila, Patrizia, Alessandro, Riccardo, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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Promises and Challenges of Immunogenic Chemotherapy in Multiple Myeloma von Johnstone, Megan, Vinaixa, Delaney, Turi, Marcello, Morelli, Eugenio, Anderson, Kenneth Carl, Gulla, Annamaria

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