Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1 von Wassermann, Ruth, Gulen, Muhammet F., Sala, Claudia, Perin, Sonia Garcia, Lou, Ye, Rybniker, Jan, Schmid-Burgk, Jonathan L., Schmidt, Tobias, Hornung, Veit, Cole, Stewart T., Ablasser, Andrea

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The cGAS–STING pathway drives type I IFN immunopathology in COVID-19 von Domizio, Jeremy Di, Gulen, Muhammet F., Saidoune, Fanny, Thacker, Vivek V., Yatim, Ahmad, Sharma, Kunal, Nass, Théo, Guenova, Emmanuella, Schaller, Martin, Conrad, Curdin, Goepfert, Christine, de Leval, Laurence, Garnier, Christophe von, Berezowska, Sabina, Dubois, Anaëlle, Gilliet, Michel, Ablasser, Andrea

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Signalling strength determines proapoptotic functions of STING von Gulen, Muhammet F., Koch, Ute, Haag, Simone M., Schuler, Fabian, Apetoh, Lionel, Villunger, Andreas, Radtke, Freddy, Ablasser, Andrea

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Cutting edge: TNF receptor-associated factor 4 restricts IL-17-mediated pathology and signaling processes von Zepp, Jarod A, Liu, Caini, Qian, Wen, Wu, Ling, Gulen, Muhammet F, Kang, Zizhen, Li, Xiaoxia

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cGAS–STING drives ageing-related inflammation and neurodegeneration von Gulen, Muhammet F., Samson, Natasha, Keller, Alexander, Schwabenland, Marius, Liu, Chong, Glück, Selene, Thacker, Vivek V., Favre, Lucie, Mangeat, Bastien, Kroese, Lona J., Krimpenfort, Paul, Prinz, Marco, Ablasser, Andrea

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The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response von Bulek, Katarzyna, Swaidani, Shadi, Qin, Jinzhong, Lu, Yi, Gulen, Muhammet F, Herjan, Tomasz, Min, Booki, Kastelein, Robert A, Aronica, Mark, Kosz-Vnenchak, Magdalena, Li, Xiaoxia

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The Receptor SIGIRR Suppresses Th17 Cell Proliferation via Inhibition of the Interleukin-1 Receptor Pathway and mTOR Kinase Activation von Gulen, Muhammet F., Kang, Zizhen, Bulek, Katarzyna, Youzhong, Wan, Kim, Tae Whan, Chen, Yi, Altuntas, Cengiz Z., Sass Bak-Jensen, Kristian, McGeachy, Mandy J., Do, Jeong-Su, Xiao, Hui, Delgoffe, Greg M., Min, Booki, Powell, Jonathan D., Tuohy, Vincent K., Cua, Daniel J., Li, Xiaoxia

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SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens von Sham, Ho Pan, Yu, Emily Yi Shan, Gulen, Muhammet F, Bhinder, Ganive, Stahl, Martin, Chan, Justin M, Brewster, Lara, Morampudi, Vijay, Gibson, Deanna L, Hughes, Michael R, McNagny, Kelly M, Li, Xiaoxia, Vallance, Bruce A

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Inactivation of the Enzyme GSK3α by the Kinase IKKi Promotes AKT-mTOR Signaling Pathway that Mediates Interleukin-1-Induced Th17 Cell Maintenance von Gulen, Muhammet F., Bulek, Katarzyna, Xiao, Hui, Yu, Minjia, Gao, Ji, Sun, Lillian, Beurel, Eleonore, Kaidanovich-Beilin, Oksana, Fox, Paul L., DiCorleto, Paul E., Wang, Jian-an, Qin, Jun, Wald, David N., Woodgett, James R., Jope, Richard S., Carman, Julie, Dongre, Ashok, Li, Xiaoxia

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Inside Job: Viruses Transfer cGAMP between Cells von Gulen, Muhammet F., Ablasser, Andrea

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Targeting STING with covalent small-molecule inhibitors von Haag, Simone M., Gulen, Muhammet F., Reymond, Luc, Gibelin, Antoine, Abrami, Laurence, Decout, Alexiane, Heymann, Michael, van der Goot, F. Gisou, Turcatti, Gerardo, Behrendt, Rayk, Ablasser, Andrea

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Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease von Bakhautdin, Bakytzhan, Febbraio, Maria, Goksoy, Esen, de la Motte, Carol A, Gulen, Muhammet F, Childers, Erin Patricia, Hazen, Stanley L, Li, Xiaoxia, Fox, Paul L

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m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner von Balzarolo, Melania, Engels, Sander, de Jong, Anja J., Franke, Katka, van den Berg, Timo K., Gulen, Muhammet F., Ablasser, Andrea, Janssen, Edith M., van Steensel, Bas, Wolkers, Monika C.

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IRAK4 Kinase Activity Is Required for Th17 Differentiation and Th17-Mediated Disease von Staschke, Kirk A, Dong, Sucai, Saha, Joy, Zhao, Jingyong, Brooks, Nathan A, Hepburn, Deena L, Xia, Jinqi, Gulen, Muhammet F, Kang, Zizhen, Altuntas, Cengiz Z, Tuohy, Vincent K, Gilmour, Raymond, Li, Xiaoxia, Na, Songqing

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The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation von Bulek, Katarzyna, Liu, Caini, Swaidani, Shadi, Wang, Liwen, Page, Richard C, Gulen, Muhammet F, Herjan, Tomasz, Abbadi, Amina, Qian, Wen, Sun, Dongxu, Lauer, Mark, Hascall, Vincent, Misra, Saurav, Chance, Mark R, Aronica, Mark, Hamilton, Thomas, Li, Xiaoxia

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IKKα negatively regulates ASC-dependent inflammasome activation von Martin, Bradley N., Wang, Chenhui, Willette-Brown, Jami, Herjan, Tomasz, Gulen, Muhammet F., Zhou, Hao, Bulek, Katarzyna, Franchi, Luigi, Sato, Takashi, Alnemri, Emad S., Narla, Goutham, Zhong, Xiao-Ping, Thomas, James, Klinman, Dennis, Fitzgerald, Katherine A., Karin, Michael, Nuñez, Gabriel, Dubyak, George, Hu, Yinling, Li, Xiaoxia

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Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability von Lee, Jacob S., Tato, Cristina M., Joyce-Shaikh, Barbara, Gulen, Muhammet F., Cayatte, Corinne, Chen, Yi, Blumenschein, Wendy M., Judo, Michael, Ayanoglu, Gulesi, McClanahan, Terrill K., Li, Xiaoxia, Cua, Daniel J.

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Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice von Zhao, Junjie, Bulek, Katarzyna, Gulen, Muhammet F, Zepp, Jarod A, Karagkounis, Georgio, Martin, Bradley N, Zhou, Hao, Yu, Minjia, Liu, Xiuli, Huang, Emina, Fox, Paul L, Kalady, Matthew F, Markowitz, Sanford D, Li, Xiaoxia

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EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis von Sala, Claudia, Odermatt, Nina T, Soler-Arnedo, Paloma, Gülen, Muhammet F, von Schultz, Sofia, Benjak, Andrej, Cole, Stewart T

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Loss of Single Immunoglobulin Interlukin-1 Receptor-Related Molecule Leads to Enhanced Colonic Polyposis in Apcmin Mice von Xiao, Hui, Yin, Weiguo, Khan, Mohammed A, Gulen, Muhammet F, Zhou, Hang, Sham, Ho Pan, Jacobson, Kevan, Vallance, Bruce A, Li, Xiaoxia

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