Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications von Marcucci, Guido, Haferlach, Torsten, Döhner, Hartmut

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Targeting microRNAs in cancer: rationale, strategies and challenges von Garzon, Ramiro, Croce, Carlo M, Marcucci, Guido

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Efficacy of the combination of venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia von Aldoss, Ibrahim, Yang, Dongyun, Aribi, Ahmed, Ali, Haris, Sandhu, Karamjeet, Al Malki, Monzr M, Mei, Matthew, Salhotra, Amandeep, Khaled, Samer, Nakamura, Ryotaro, Snyder, David, O'Donnell, Margaret, Stein, Anthony S, Forman, Stephen J, Marcucci, Guido, Pullarkat, Vinod

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Targeting miR-126 in inv(16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance von Zhang, Lianjun, Nguyen, Le Xuan Truong, Chen, Ying-Chieh, Wu, Dijiong, Cook, Guerry J., Hoang, Dinh Hoa, Brewer, Casey J., He, Xin, Dong, Haojie, Li, Shu, Li, Man, Zhao, Dandan, Qi, Jing, Hua, Wei-Kai, Cai, Qi, Carnahan, Emily, Chen, Wei, Wu, Xiwei, Swiderski, Piotr, Rockne, Russell C., Kortylewski, Marcin, Li, Ling, Zhang, Bin, Marcucci, Guido, Kuo, Ya-Huei

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Correlates of resistance and relapse during blinatumomab therapy for relapsed/refractory acute lymphoblastic leukemia von Aldoss, Ibrahim, Song, Joo, Stiller, Tracey, Nguyen, Tina, Palmer, Joycelynne, O'Donnell, Margaret, Stein, Anthony S., Marcucci, Guido, Forman, Stephen, Pullarkat, Vinod

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Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics von Koo, Gi-Bang, Morgan, Michael J, Lee, Da-Gyum, Kim, Woo-Jung, Yoon, Jung-Ho, Koo, Ja Seung, Kim, Seung Il, Kim, Soo Jung, Son, Mi Kwon, Hong, Soon Sun, Levy, Jean M Mulcahy, Pollyea, Daniel A, Jordan, Craig T, Yan, Pearlly, Frankhouser, David, Nicolet, Deedra, Maharry, Kati, Marcucci, Guido, Choi, Kyeong Sook, Cho, Hyeseong, Thorburn, Andrew, Kim, You-Sun

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Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting von Viola, Domenico, Dona, Ada, Caserta, Enrico, Troadec, Estelle, Besi, Francesca, McDonald, Tinisha, Ghoda, Lucy, Gunes, Emine Gulsen, Sanchez, James F., Khalife, Jihane, Martella, Marianna, Karanes, Chatchada, Htut, Myo, Wang, Xiuli, Rosenzweig, Michael, Chowdhury, Arnab, Sborov, Douglas, Miles, Rodney R., Yazaki, Paul J., Ebner, Todd, Hofmeister, Craig C., Forman, Stephen J., Rosen, Steven T., Marcucci, Guido, Shively, John, Keats, Jonathan J., Krishnan, Amrita, Pichiorri, Flavia

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Expression and prognostic impact of lncRNAs in acute myeloid leukemia von Garzon, Ramiro, Volinia, Stefano, Papaioannou, Dimitrios, Nicolet, Deedra, Kohlschmidt, Jessica, Yan, Pearlly S, Mrózek, Krzysztof, Bucci, Donna, Carroll, Andrew J, Baer, Maria R, Wetzler, Meir, Carter, Thomas H, Powell, Bayard L, Kolitz, Jonathan E, Moore, Joseph O, Eisfeld, Ann-Kathrin, Blachly, James S, Blum, William, Caligiuri, Michael A, Stone, Richard M, Marcucci, Guido, Croce, Carlo M, Byrd, John C, Bloomfield, Clara D

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Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia von Ranganathan, Parvathi, Yu, Xueyan, Na, Caroline, Santhanam, Ramasamy, Shacham, Sharon, Kauffman, Michael, Walker, Alison, Klisovic, Rebecca, Blum, William, Caligiuri, Michael, Croce, Carlo M., Marcucci, Guido, Garzon, Ramiro

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Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia von MROZEK, Krzysztof, MARCUCCI, Guido, PETTENATI, Mark J, HEEREMA, Nyla A, BLOCK, Annemarie W, PATIL, Shivanand R, BAER, Maria R, KOLITZ, Jonathan E, MOORE, Joseph O, CARROLL, Andrew J, STONE, Richard M, LARSON, Richard A, NICOLET, Deedra, BLOOMFIELD, Clara D, MAHARRY, Kati S, BECKER, Heiko, WHITMAN, Susan P, METZELER, Klaus H, SCHWIND, Sebastian, WU, Yue-Zhong, KOHLSCHMIDT, Jessica

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Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial von Larson, Richard A., Mandrekar, Sumithra J., Huebner, Lucas J., Sanford, Ben L., Laumann, Kristina, Geyer, Susan, Bloomfield, Clara D., Thiede, Christian, Prior, Thomas W., Döhner, Konstanze, Marcucci, Guido, Voso, Maria Teresa, Klisovic, Rebecca B., Galinsky, Ilene, Wei, Andrew H., Sierra, Jorge, Sanz, Miguel A., Brandwein, Joseph M., de Witte, Theo, Niederwieser, Dietger, Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Krauter, Jürgen, Schlenk, Richard F., Ganser, Arnold, Serve, Hubert, Ehninger, Gerhard, Amadori, Sergio, Gathmann, Insa, Döhner, Hartmut, Stone, Richard M.

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MicroRNA 29b functions in acute myeloid leukemia von Garzon, Ramiro, Heaphy, Catherine E.A., Havelange, Violaine, Fabbri, Muller, Volinia, Stefano, Tsao, Twee, Zanesi, Nicola, Kornblau, Steven M., Marcucci, Guido, Calin, George A., Andreeff, Michael, Croce, Carlo M.

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IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study von MARCUCCI, Guido, MAHARRY, Kati, METZELER, Klaus H, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, CALIGIURI, Michael A, LARSON, Richard A, BLOOMFIELD, Clara D, WU, Yue-Zhong, RADMACHER, Michael D, MROZEK, Krzysztof, MARGESON, Dean, HOLLAND, Kelsi B, WHITMAN, Susan P, BECKER, Heiko, SCHWIND, Sebastian

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Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia von Zhang, Bin, Nguyen, Le Xuan Truong, Li, Ling, Zhao, Dandan, Kumar, Bijender, Wu, Herman, Lin, Allen, Pellicano, Francesca, Hopcroft, Lisa, Su, Yu-Lin, Copland, Mhairi, Holyoake, Tessa L, Kuo, Calvin J, Bhatia, Ravi, Snyder, David S, Ali, Haris, Stein, Anthony S, Brewer, Casey, Wang, Huafeng, McDonald, Tinisha, Swiderski, Piotr, Troadec, Estelle, Chen, Ching-Cheng, Dorrance, Adrienne, Pullarkat, Vinod, Yuan, Yate-Ching, Perrotti, Danilo, Carlesso, Nadia, Forman, Stephen J, Kortylewski, Marcin, Kuo, Ya-Huei, Marcucci, Guido

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MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B von Fabbri, Muller, Garzon, Ramiro, Cimmino, Amelia, Liu, Zhongfa, Zanesi, Nicola, Callegari, Elisa, Liu, Shujun, Alder, Hansjuerg, Costinean, Stefan, Fernandez-Cymering, Cecilia, Volinia, Stefano, Guler, Gulnur, Morrison, Carl D, Chan, Kenneth K, Marcucci, Guido, Calin, George A, Huebner, Kay, Croce, Carlo M

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Inhibition of the receptor tyrosine kinase Axl impedes activation of the FLT3 internal tandem duplication in human acute myeloid leukemia: implications for Axl as a potential thera... von Park, Il-Kyoo, Mishra, Anjali, Chandler, Jason, Whitman, Susan P., Marcucci, Guido, Caligiuri, Michael A.

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 von Garzon, Ramiro, Liu, Shujun, Fabbri, Muller, Liu, Zhongfa, Heaphy, Catherine E.A., Callegari, Elisa, Schwind, Sebastian, Pang, Jiuxia, Yu, Jianhua, Muthusamy, Natarajan, Havelange, Violaine, Volinia, Stefano, Blum, William, Rush, Laura J., Perrotti, Danilo, Andreeff, Michael, Bloomfield, Clara D., Byrd, John C., Chan, Kenneth, Wu, Lai-Chu, Croce, Carlo M., Marcucci, Guido

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Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine von Blum, William, Garzon, Ramiro, Klisovic, Rebecca B, Schwind, Sebastian, Walker, Alison, Geyer, Susan, Liu, Shujun, Havelange, Violaine, Becker, Heiko, Schaaf, Larry, Mickle, Jon, Devine, Hollie, Kefauver, Cheryl, Devine, Steven M, Chan, Kenneth K, Heerema, Nyla A, Bloomfield, Clara D, Grever, Michael R, Byrd, John C, Villalona-Calero, Miguel, Croce, Carlo M, Marcucci, Guido

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Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia von XIAOMENG HUANG, SCHWIND, Sebastian, BLUM, William, PERROTTI, Danilo, BYRD, John C, BLOOMFIELD, Clara D, CALIGIURI, Michael A, LEE, Robert J, GARZON, Ramiro, MUTHUSAMY, Natarajan, LEE, Ly James, MARCUCCI, Guido, BO YU, SANTHANAM, Ramasamy, HONGYAN WANG, HOELLERBAUER, Pia, MIMS, Alice, KLISOVIC, Rebecca, WALKER, Alison R, CHAN, Kenneth K

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HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity von Hua, Wei-Kai, Qi, Jing, Cai, Qi, Carnahan, Emily, Ayala Ramirez, Maria, Li, Ling, Marcucci, Guido, Kuo, Ya-Huei

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