Acridone-Based Inhibitors of Inosine 5‘-Monophosphate Dehydrogenase:  Discovery and SAR Leading to the Identification of N-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2-... von Watterson, Scott H, Chen, Ping, Zhao, Yufen, Gu, Henry H, Dhar, T. G. Murali, Xiao, Zili, Ballentine, Shelley K, Shen, Zhongqi, Fleener, Catherine A, Rouleau, Katherine A, Obermeier, Mary, Yang, Zheng, McIntyre, Kim W, Shuster, David J, Witmer, Mark, Dambach, Donna, Chao, Sam, Mathur, Arvind, Chen, Bang-Chi, Barrish, Joel C, Robl, Jeffrey A, Townsend, Robert, Iwanowicz, Edwin J

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3-Cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: Synthesis and initial structure-activity relationships von MURALI DHAR, T. G, ZHONGQI SHEN, TOWNSEND, Robert, HOLLENBAUGH, Diane L, IWANOWICZ, Edwin J, GU, Henry H, PING CHEN, NORRIS, Derek, WATTERSON, Scott H, BALLENTINE, Shelley K, FLEENER, Catherine A, ROULEAU, Katherine A, BARRISH, Joel C

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A Modified Approach to 2-(N-Aryl)-1,3-oxazoles:  Application to the Synthesis of the IMPDH Inhibitor BMS-337197 and Analogues von Dhar, T. G. Murali, Guo, Junqing, Shen, Zhongqi, Pitts, William J, Gu, Henry H, Chen, Bang-Chi, Zhao, Rulin, Bednarz, Mark S, Iwanowicz, Edwin J

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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56(Lck) von Chen, Ping, Norris, Derek, Iwanowicz, Edwin J, Spergel, Steven H, Lin, James, Gu, Henry H, Shen, Zhongqi, Wityak, John, Lin, Tai-An, Pang, Suhong, De Fex, Henry F, Pitt, Sidney, Shen, Ding Ren, Doweyko, Arthur M, Bassolino, Donna A, Roberge, Jacques Y, Poss, Michael A, Chen, Bang-Chi, Schieven, Gary L, Barrish, Joel C

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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck von PING CHEN, NORRIS, Derek, DE FEX, Henry F, PITT, Sidney, DING REN SHEN, DOWEYKO, Arthur M, BASSOLINO, Donna A, ROBERGE, Jacques Y, POSS, Michael A, CHEN, Bang-Chi, SCHIEVEN, Gary L, BARRISH, Joel C, IWANOWICZ, Edwin J, SPERGEL, Steven H, LIN, James, GU, Henry H, ZHONGQI SHEN, WITYAK, John, LIN, Tai-An, SUHONG PANG

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Novel diamide-Based inhibitors of IMPDH von Gu, Henry H., Iwanowicz, Edwin J., Guo, Junqing, Watterson, Scott H., Shen, Zhongqi, Pitts, William J., Dhar, T.G.Murali, Fleener, Catherine A., Rouleau, Katherine, Sherbina, N.Z., Witmer, Mark, Tredup, Jeffrey, Hollenbaugh, Diane

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Discovery of N-[2-[2-[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a Novel and Potent Inhibitor of Inosine Monophosphate Dehydrogena... von Dhar, T. G. Murali, Shen, Zhongqi, Guo, Junqing, Liu, Chunjian, Watterson, Scott H, Gu, Henry H, Pitts, William J, Fleener, Catherine A, Rouleau, Katherine A, Sherbina, N. Z, McIntyre, Kim W, Witmer, Mark R, Tredup, Jeffrey A, Chen, Bang-Chi, Zhao, Rulin, Bednarz, Mark S, Cheney, Daniel L, MacMaster, John F, Miller, Laura M, Berry, Karen K, Harper, Timothy W, Barrish, Joel C, Hollenbaugh, Diane L, Iwanowicz, Edwin J

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Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase von Pitts, William J., Guo, Junqing, Dhar, T.G.Murali, Shen, Zhongqi, Gu, Henry H., Watterson, Scott H., Bednarz, Mark S., Chen, Bang-Chi, Barrish, Joel C., Bassolino, Donna, Cheney, Daniel, Fleener, Catherine A., Rouleau, Katherine A., Hollenbaugh, Diane L., Iwanowicz, Edwin J.

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Synthesis and SAR of novel imidazoquinoxaline-Based Lck inhibitors: improvement of cell potency von Chen, Ping, Iwanowicz, Edwin J., Norris, Derek, Gu, Henry H., Lin, James, Moquin, Robert V., Das, Jagabandhu, Wityak, John, Spergel, Steven H., de Fex, Henry, Pang, Suhong, Pitt, Sydney, Shen, Ding Ren, Schieven, Gary L., Barrish, Joel C.

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Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-Methoxy-4-(5-oxazolyl)phenyl moiety von Iwanowicz, Edwin J., Watterson, Scott H., Guo, Junqing, Pitts, William J., Murali Dhar, T.G., Shen, Zhongqi, Chen, Ping, Gu, Henry H., Fleener, Catherine A., Rouleau, Katherine A., Cheney, Daniel L., Townsend, Robert M., Hollenbaugh, Diane L.

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Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase von IWANOWICZ, Edwin J, WATTERSON, Scott H, HOLLENBAUGH, Diane L, CHUNJIAN LIU, GU, Henry H, MITT, Toomas, LEFTHERIS, Katerina, BARRISH, Joel C, FLEENER, Catherine A, ROULEAU, Katherine, SHERBINA, N. Z

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Novel inhibitors of IMPDH: a highly potent and selective quinolone-based series von Watterson, Scott H., Carlsen, Marianne, Murali Dhar, T.G., Shen, Zhongqi, Pitts, William J., Guo, Junqing, Gu, Henry H., Norris, Derek, Chorba, John, Chen, Ping, Cheney, Daniel, Witmer, Mark, Fleener, Catherine A., Rouleau, Katherine, Townsend, Robert, Hollenbaugh, Diane L., Iwanowicz, Edwin J.

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Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase von WATTERSON, Scott H, CHUNJIAN LIU, IWANOWICZ, Edwin J, MURALI DHAR, T. G, GU, Henry H, PITTS, William J, BARRISH, Joel C, FLEENER, Catherine A, ROULEAU, Katherine, SHERBINA, N. Z, HOLLENBAUGH, Diane L

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Quinolone-Based IMPDH inhibitors: introduction of basic residues on ring D and SAR of the corresponding mono, di and benzofused analogues von Dhar, T.G.Murali, Watterson, Scott H., Chen, Ping, Shen, Zhongqi, Gu, Henry H., Norris, Derek, Carlsen, Marianne, Haslow, Kristin D., Pitts, William J., Guo, Junqing, Chorba, John, Fleener, Catherine A., Rouleau, Katherine A., Townsend, Robert, Hollenbaugh, Diane, Iwanowicz, Edwin J.

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Imidazoquinoxaline Src-Family Kinase p56Lck Inhibitors:  SAR, QSAR, and the Discovery of (S)-N-(2-Chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyra... von Chen, Ping, Doweyko, Arthur M, Norris, Derek, Gu, Henry H, Spergel, Steven H, Das, Jagabundhu, Moquin, Robert V, Lin, James, Wityak, John, Iwanowicz, Edwin J, McIntyre, Kim W, Shuster, David J, Behnia, Kamelia, Chong, Saeho, de Fex, Henry, Pang, Suhong, Pitt, Sydney, Shen, Ding Ren, Thrall, Sara, Stanley, Paul, Kocy, Octavian R, Witmer, Mark R, Kanner, Steven B, Schieven, Gary L, Barrish, Joel C

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Discovery of N-[2-[2-[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4-morpholineacetamide as a Novel and Potent Inhibitor of Inosine Monophosphate Dehydrogenas... von Murali Dhar, T. G, Shen, Zhongqi, Guo, Junqing, Liu, Chunjian, Watterson, Scott H, Gu, Henry H, Pitts, William J, Fleener, Catherine A, Rouleau, Katherine A, Sherbina, N. Z, McIntyre, Kim W, Shuster, David J, Witmer, Mark R, Tredup, Jeffrey A, Chen, Bang-Chi, Zhao, Rulin, Bednarz, Mark S, Cheney, Daniel L, MacMaster, John F, Miller, Laura M, Berry, Karen K, Harper, Timothy W, Barrish, Joel C, Hollenbaugh, Diane L, Iwanowicz, Edwin J

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Imidazoquinoxaline Src-Family Kinase p56 Lck Inhibitors:  SAR, QSAR, and the Discovery of ( S )- N -(2-Chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5- a ]pyrido[3,2... von Chen, Ping, Doweyko, Arthur M., Norris, Derek, Gu, Henry H., Spergel, Steven H., Das, Jagabundhu, Moquin, Robert V., Lin, James, Wityak, John, Iwanowicz, Edwin J., McIntyre, Kim W., Shuster, David J., Behnia, Kamelia, Chong, Saeho, de Fex, Henry, Pang, Suhong, Pitt, Sydney, Shen, Ding Ren, Thrall, Sara, Stanley, Paul, Kocy, Octavian R., Witmer, Mark R., Kanner, Steven B., Schieven, Gary L., Barrish, Joel C.

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Novel inhibitors of IMPDH von Watterson, Scott H., Carlsen, Marianne, Murali Dhar, T.G., Shen, Zhongqi, Pitts, William J., Guo, Junqing, Gu, Henry H., Norris, Derek, Chorba, John, Chen, Ping, Cheney, Daniel, Witmer, Mark, Fleener, Catherine A., Rouleau, Katherine, Townsend, Robert, Hollenbaugh, Diane L., Iwanowicz, Edwin J.

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Reaction of tetracarbonyl(π-allyl)manganese with carbon nucleophiles von Vaughan, William S., Gu, Henry H., McDaniel, Keith F.

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The Enantioselective Synthesis of anti-β-Hydroxy-α-Amino Acids via the Reaction of Lithium Enolates of Glycine Bearing an Oxazolidine Chiral Auxiliary with Aldehydes von Iwanowicz, Edwin J., Blomgren, Peter, Cheng, Peter T. W., Smith, Kennith, Lau, Wan F., Pan, Yolanda Y., Gu, Henry H., Malley, Mary F., Gougoutas, Jack Z.

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