Biomarkers in newly diagnosed pediatric-extensive chronic graft-versus-host disease: a report from the Children's Oncology Group von Fujii, Hisaki, Cuvelier, Geoff, She, Kevin, Aslanian, Soudabeh, Shimizu, Hiromi, Kariminia, Amina, Krailo, Mark, Chen, Zhengjia, McMaster, Rob, Bergman, Axel, Goldman, Frederick, Grupp, Stephen A., Wall, Donna A., Gilman, Andrew L., Schultz, Kirk R.

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Tisagenlecleucel for treatment of children and young adults with relapsed/refractory B‐cell acute lymphoblastic leukemia von Si Lim, Stephanie J., Grupp, Stephen A., DiNofia, Amanda M.

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Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy von Bhoj, Vijay G., Arhontoulis, Dimitrios, Wertheim, Gerald, Capobianchi, James, Callahan, Colleen A., Ellebrecht, Christoph T., Obstfeld, Amrom E., Lacey, Simon F., Melenhorst, Jan J., Nazimuddin, Farzana, Hwang, Wei-Ting, Maude, Shannon L., Wasik, Mariusz A., Bagg, Adam, Schuster, Stephen, Feldman, Michael D., Porter, David L., Grupp, Stephen A., June, Carl H., Milone, Michael C.

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Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species von Goodell, Margaret A, Rosenzweig, Michael, Kim, Hyung, Marks, Douglas F, DeMaria, MaryAnn, Paradis, Glenn, Grupp, Stephen A, Sieff, Colin A, Mulligan, Richard C, Johnson, R. Paul

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Myeloablative Busulfan/Melphalan Consolidation following Induction Chemotherapy for Patients with Newly Diagnosed High-Risk Neuroblastoma: Children's Oncology Group Trial ANBL12P1 von Granger, M. Meaghan, Naranjo, Arlene, Bagatell, Rochelle, DuBois, Steven G., McCune, Jeannine S., Tenney, Sheena C., Weiss, Brian D., Mosse, Yael P., Asgharzadeh, Shahab, Grupp, Stephen A., Hogarty, Michael D., Gastier-Foster, Julie M., Mills, Denise, Shulkin, Barry L., Parisi, Marguerite T., London, Wendy B., Han-Chang, John, Panoff, Joseph, von Allmen, Daniel, Jarzembowski, Jason A., Park, Julie R., Yanik, Gregory A.

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Primary tumor control in patients with stage 3/4 unfavorable neuroblastoma treated with tandem double autologous stem cell transplants von MARCUS, Karen J, SHAMBERGER, Robert, LITMAN, Heather, VON ALLMEN, Daniel, GRUPP, Stephen A, MEDEIROS NANCARROW, Cheryl, GOLDWEIN, Joel, GRIER, Holcombe E, DILLER, Lisa

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Minimally Ex Vivo Manipulated Gene-Modified T Cells Display Enhanced Tumor Control von Ghassemi, Saba, Prachi, Patel, Scholler, John, Nunez-Cruz, Selene, Barrett, David M., Bedoya, Felipe, Fraietta, Joseph A., Lacey, Simon Francis, Levine, Bruce L, Grupp, Stephen A., June, Carl H, Milone, Michael C., Melenhorst, J. Joseph

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Abstract 3143: Alternative splicing of CD19 mRNA in leukemias escaping CART-19 immunotherapy eliminates the cognate epitope and contributes to treatment failure von Sotillo, Elena, Barrett, David, Bagashev, Aseb, Black, Kathryn, Lanauze, Caludia, Oldridge, Derek, Sussman, Robyn, Harrington, Colleen, Chung, Elaine Y., Hofmann, Ted J., Maude, Shannon L., Martinez, Nicole M., Raman, Pichai, Ruella, Marco, Allman, David, Jacoby, Elad, Fry, Terry, Barash, Yoseph, Lynch, Kristen W., Mackall, Crystal, Maris, John, Grupp, Stephen A., Thomas-Tikhonenko, Andrei

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Neuroblastoma: Issues in Transplantation von Grupp, Stephan A, Asgharzadeh, Shahab, Yanik, Gregory A

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Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia von Tasian, Sarah K., Teachey, David T., Li, Yong, Shen, Feng, Harvey, Richard C., Chen, I-Ming, Ryan, Theresa, Vincent, Tiffaney L., Willman, Cheryl L., Perl, Alexander E., Hunger, Stephen P., Loh, Mignon L., Carroll, Martin, Grupp, Stephan A.

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Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial von Park, Julie R, Kreissman, Susan G, London, Wendy B, Naranjo, Arlene, Cohn, Susan Lerner, Hogarty, Michael D, Tenney, Sheena C, Haas-Kogan, Daphne, Shaw, Peter John, Kraveka, Jacqueline M, Roberts, Stephen S, Geiger, James Duncan, Doski, John J, Voss, Stephan D, Maris, John M, Grupp, Stephan A, Diller, Lisa

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Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia von Maude, Shannon L., Tasian, Sarah K., Vincent, Tiffaney, Hall, Junior W., Sheen, Cecilia, Roberts, Kathryn G., Seif, Alix E., Barrett, David M., Chen, I-Ming, Collins, J. Racquel, Mullighan, Charles G., Hunger, Stephen P., Harvey, Richard C., Willman, Cheryl L., Fridman, Jordan S., Loh, Mignon L., Grupp, Stephan A., Teachey, David T.

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Impact of high-risk cytogenetics on outcomes for children and young adults receiving CD19-directed CAR T-cell therapy von Leahy, Allison Barz, Devine, Kaitlin J., Li, Yimei, Liu, Hongyan, Myers, Regina, DiNofia, Amanda, Wray, Lisa, Rheingold, Susan R., Callahan, Colleen, Baniewicz, Diane, Patino, Maria, Newman, Haley, Hunger, Stephen P., Grupp, Stephan A., Barrett, David M., Maude, Shannon L.

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Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia von Bride, Karen L., Vincent, Tiffaney L., Im, Soo-Yeon, Aplenc, Richard, Barrett, David M., Carroll, William L., Carson, Robin, Dai, Yunfeng, Devidas, Meenakshi, Dunsmore, Kimberly P., Fuller, Tori, Glisovic-Aplenc, Tina, Horton, Terzah M., Hunger, Stephen P., Loh, Mignon L., Maude, Shannon L., Raetz, Elizabeth A., Winter, Stuart S., Grupp, Stephan A., Hermiston, Michelle L., Wood, Brent L., Teachey, David T.

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Higher Reported Lung Dose Received During Total Body Irradiation for Allogeneic Hematopoietic Stem Cell Transplantation in Children With Acute Lymphoblastic Leukemia Is Associated... von Esiashvili, Natia, Lu, Xiaomin, Ulin, Ken, Laurie, Fran, Kessel, Sandy, Kalapurakal, John A., Merchant, Thomas E., Followill, David S., Sathiaseelan, Vythialinga, Schmitter, Mary K., Devidas, Meenakshi, Chen, Yichen, Wall, Donna A., Brown, Patrick A., Hunger, Stephen P., Grupp, Stephan A., Pulsipher, Michael A.

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Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia von Maude, Shannon L., Dolai, Sibasish, Delgado-Martin, Cristina, Vincent, Tiffaney, Robbins, Alissa, Selvanathan, Arthavan, Ryan, Theresa, Hall, Junior, Wood, Andrew C., Tasian, Sarah K., Hunger, Stephen P., Loh, Mignon L., Mullighan, Charles G., Wood, Brent L., Hermiston, Michelle L., Grupp, Stephan A., Lock, Richard B., Teachey, David T.

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Nonviral RNA chimeric antigen receptor–modified T cells in patients with Hodgkin lymphoma von Svoboda, Jakub, Rheingold, Susan R., Gill, Saar I., Grupp, Stephan A., Lacey, Simon F., Kulikovskaya, Irina, Suhoski, Megan M., Melenhorst, J. Joseph, Loudon, Brandon, Mato, Anthony R., Nasta, Sunita Dwivedy, Landsburg, Daniel J., Youngman, Matthew R., Levine, Bruce L., Porter, David L., June, Carl H., Schuster, Stephen J.

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CAR T cell viability release testing and clinical outcomes: is there a lower limit? von Chong, Elise A., Levine, Bruce L., Grupp, Stephan A., Davis, Megan M., Siegel, Don L., Maude, Shannon L., Gladney, Whitney L., Frey, Noelle V., Porter, David L., Hwang, Wei-Ting, Chong, Emeline R., June, Carl H., Schuster, Stephen J.

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Long Term Durable Responses in Relapsed/Refractory (r/r) ALL, DLBCL, and FL Patients Treated with Tisagenlecleucel and Its Association with Persistence of CAR T-Cells von Awasthi, Rakesh, Waldron, Edward, Grupp, Stephan, Pulsipher, Michael A., Bader, Peter, Schuster, Stephen J, Maziarz, Richard T, Waller, Edmund K., Jaeger, Ulrich, Thieblemont, Catherine, Dreyling, Martin, Fowler, Nathan, Maier, Harald Jakob, Willert, Jennifer

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Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia von Roberts, Kathryn G., Morin, Ryan D., Zhang, Jinghui, Hirst, Martin, Zhao, Yongjun, Su, Xiaoping, Chen, Shann-Ching, Payne-Turner, Debbie, Churchman, Michelle L., Harvey, Richard C., Chen, Xiang, Kasap, Corynn, Yan, Chunhua, Becksfort, Jared, Finney, Richard P., Teachey, David T., Maude, Shannon L., Tse, Kane, Moore, Richard, Jones, Steven, Mungall, Karen, Birol, Inanc, Edmonson, Michael N., Hu, Ying, Buetow, Kenneth E., Chen, I-Ming, Carroll, William L., Wei, Lei, Ma, Jing, Kleppe, Maria, Levine, Ross L., Garcia-Manero, Guillermo, Larsen, Eric, Shah, Neil P., Devidas, Meenakshi, Reaman, Gregory, Smith, Malcolm, Paugh, Steven W., Evans, William E., Grupp, Stephan A., Jeha, Sima, Pui, Ching-Hon, Gerhard, Daniela S., Downing, James R., Willman, Cheryl L., Loh, Mignon, Hunger, Stephen P., Marra, Marco A., Mullighan, Charles G.

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