Invited review: Drug development for tauopathies von Gruninger, Fiona

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Region-specific permeability of the blood–brain barrier upon pericyte loss von Villaseñor, Roberto, Kuennecke, Basil, Ozmen, Laurence, Ammann, Michelle, Kugler, Christof, Grüninger, Fiona, Loetscher, Hansruedi, Freskgård, Per-Ola, Collin, Ludovic

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Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supran... von Piras, Antonio, Collin, Ludovic, Grüninger, Fiona, Graff, Caroline, Rönnbäck, Annica

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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier von Villaseñor, Roberto, Ozmen, Laurence, Messaddeq, Nadia, Grüninger, Fiona, Loetscher, Hansruedi, Keller, Annika, Betsholtz, Christer, Freskgård, Per-Ola, Collin, Ludovic

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Discovery of Orally Available and Brain Penetrant AEP Inhibitors von Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn

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Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies von Easton, Amy, Jensen, Marianne L., Wang, Congwei, Hagedorn, Peter H., Li, Yuwen, Weed, Michael, Meredith, Jere E., Guss, Valerie, Jones, Kelli, Gill, Martin, Krause, Carol, Brown, Jeffrey M., Hunihan, Lisa, Natale, Joanne, Fernandes, Alda, Lu, Yifeng, Polino, Joe, Bookbinder, Mark, Cadelina, Greg, Benitex, Yulia, Sane, Ramola, Morrison, John, Drexler, Dieter, Mercer, Stephen E., Bon, Charlotte, Pandya, Nikhil J., Jagasia, Ravi, Ou Yang, Tai-Hsien, Distler, Tania, Grüninger, Fiona, Meldgaard, Michael, Terrigno, Marco, Macor, John E., Albright, Charles F., Loy, James, Hoeg, Anja M., Olson, Richard E., Cacace, Angela M.

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Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease von COLLIN, Ludovic, BOHRMANN, Bernd, GÖPFERT, Ulrich, OROSZLAN-SZOVIK, Krisztina, OZMEN, Laurence, GRÜNINGER, Fiona

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A fluorine scan of non-peptidic inhibitors of neprilysin: Fluorophobic and fluorophilic regions in an enzyme active site von Morgenthaler, Martin, Aebi, Johannes D., Grüninger, Fiona, Mona, Daniel, Wagner, Björn, Kansy, Manfred, Diederich, François

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Identification of β-secretase-like activity using a mass spectrometry-based assay system von Döbeli, Heinz, Grüninger-Leitch, Fiona, Berndt, Peter, Langen, Hanno, Nelboeck, Peter

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Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation von Wang, Congwei, Terrigno, Marco, Li, Juan, Distler, Tania, Pandya, Nikhil J., Ebeling, Martin, Tyanova, Stefka, Hoozemans, Jeroen J.M., Dijkstra, Anke A., Fuchs, Luisa, Xiang, Shengqi, Bonni, Azad, Grüninger, Fiona, Jagasia, Ravi

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Human napsin A: expression, immunochemical detection, and tissue localization von Schauer-Vukasinovic, Vesna, Bur, Daniel, Kling, Dorothee, Grüninger, Fiona, Giller, Thomas

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Crystal structure of phytase from Aspergillus ficuum at 2.5 Å resolution von Kostrewa, Dirk, Grüninger-Leitch, Fiona, D′Arcy, Allan, Broger, Clemens, Mitchell, David, van Loon, Adolphus P. G. M

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BACE/APPV717F Double-Transgenic Mice Develop Cerebral Amyloidosis and Inflammation von Ozmen, Laurence, Woolley, Marie, Albientz, Anita, Miss, Marie-Therese, Nelboeck, Peter, Malherbe, Pari, Czech, Christian, Grüninger-Leitch, Fiona, Brockhaus, Manfred, Ballard, Theresa, Jacobsen, Helmut

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Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer‘s disease von Collin, Ludovic, Bohrmann, Bernd, Göpfert, Ulrich, Oroszlan-Szovik, Krisztina, Ozmen, Laurence, Grüninger, Fiona

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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier von Villaseñor, Roberto, Ozmen, Laurence, Messaddeq, Nadia, Grüninger, Fiona, Loetscher, Hansruedi, Keller, Annika, Betsholtz, Christer, Freskgård, Per-Ola, Collin, Ludovic

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Substrate and Inhibitor Profile of BACE (β-Secretase) and Comparison with Other Mammalian Aspartic Proteases von Grueninger-Leitch, F, Schlatter, D, Kueng, E, Nelboeck, P, Doebeli, H

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P3‐328: Reduction of phosphorylated tau aggregates in TauPS2APP transgenic mice by passive immunotherapy with an anti‐tau/pS422 antibody von Grüninger, Fiona, Collin, Ludovic, Laurence, Ozmen, Oroszlan‐Szovik, Krisztina, Schraeml, Michael, Mundigl, Olaf, Goepfert, Ulrich, Bohrmann, Bernd

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Reduction of phosphorylated tau aggregates in TauPS2APP transgenic mice by passive immunotherapy with an anti-tau/pS422 antibody von Grüninger, Fiona, Collin, Ludovic, Laurence, Ozmen, Oroszlan-Szovik, Krisztina, Schraeml, Michael, Mundigl, Olaf, Goepfert, Ulrich, Bohrmann, Bernd

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Point mutations in conserved amino acid residues within the C-terminal domain of HIV-1 reverse transcriptase specifically repress RNase H function von Schatz, Octavian, Cromme, Frans V., Grüninger-Leitch, Fiona, Le Grice, Stuart F.J.

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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier von Villasenor, Roberto, Ozmen, Laurence, Messaddeq, Nadia, Gruninger, Fiona, Loetscher, Hansruedi, Keller, Annika, Betsholtz, Christer, Freskgard, Per-Ola, Collin, Ludovic

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