Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS von ZUIDERVAART, W, VAN NIEUWPOORT, F, HAYWARD, N. K, GRUIS, N. A, STARK, M, DIJKMAN, R, PACKER, L, BORGSTEIN, A.-M, PAVEY, S, VAN DER VELDEN, P, OUT, C, JAGER, M. J

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Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden) von VASEN, H. F. A, GRUIS, N. A, FRANTS, R. R, VAN DER VELDEN, P. A, HILLE, E. T. M, BERGMAN, W

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GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi von Vader, M J C, Madigan, M C, Versluis, M, Suleiman, H M, Gezgin, G, Gruis, N A, Out-Luiting, J J, Bergman, W, Verdijk, R M, Jager, M J, van der Velden, P A

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A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types von Kamb, Alexander, Gruis, Nelleke A., Weaver-Feldhaus, Jane, Liu, Qingyun, Harshman, Keith, Tavtigian, Sean V., Stockert, Elisabeth, Day, Rufus S., Johnson, Bruce E., Skolnick, Mark H.

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Analysis of the p16 gene ( CDKN2 ) as a candidate for the chromosome 9p melanoma susceptibility locus von Kamb, A, Shattuck-Eidens, D, Eeles, R, Liu, Q, Gruis, N. A, Ding, W, Hussey, C, Tran, T, Miki, Y, Weaver-Feldhaus, J, McClure, M, Aitken, J. F, Anderson, D. E, Bergman, W, Frants, R, Goldgar, D. E, Green, A, MacLennan, R, Martin, N. G, Meyer, L. J, Youl, P, Zone, J. J, Skolnick, M. H, Cannon-Albright, L. A

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Gene expression profiling identifies tumour markers potentially playing a role in uveal melanoma development von ZUIDERVAART, W, VAN DER VELDEN, P. A, HURKS, M. H, VAN NIEUWPOORT, F. A, OUT-LUITING, C. J. J, SINGH, A. D, FRANTS, R. R, JAGER, M. J, GRUIS, N. A

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Episodic Src activation in uveal melanoma revealed by kinase activity profiling von Maat, W, Filali, M el, Mulder, A Dirks, Luyten, G P M, Gruis, N A, Desjardins, L, Boender, P, Jager, M J, van der Velden, P A

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MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M‐SKIP project von Stefanaki, I., Stratigos, A.J., Kypreou, K.P., Evangelou, E., Gandini, S., Maisonneuve, P., Polsky, D., Lazovich, D., Newton‐Bishop, J., Kanetsky, P.A., Puig, S., Gruis, N.A., Ghiorzo, P., Pellegrini, C., De Nicolo, A., Ribas, G., Guida, G., Garcia‐Borron, J.C., Fargnoli, M.C., Nan, H., Landi, M.T., Little, J., Sera, F., Raimondi, S.

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Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds von Gruis, Nelleke A, van der Velden, Pieter A, Sandkuijl, Lodewijk A, Prins, Duncan E, Weaver-Feldhaus, Jane, Kamb, Alexander, Bergman, Wilma, Frants, Rune R

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Cutaneous melanoma: Medical specialists' opinions on follow-up and sentinel lymph node biopsy von Wevers, K.P, Hoekstra-Weebers, J.E.H.M, Speijers, M.J, Bergman, W, Gruis, N.A, Hoekstra, H.J

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MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project von Tagliabue, Elena, Gandini, Sara, Bellocco, Rino, Maisonneuve, Patrick, Newton-Bishop, Julia, Polsky, David, Lazovich, DeAnn, Kanetsky, Peter A, Ghiorzo, Paola, Gruis, Nelleke A, Landi, Maria Teresa, Menin, Chiara, Fargnoli, Maria Concetta, García-Borrón, Jose Carlos, Han, Jiali, Little, Julian, Sera, Francesco, Raimondi, Sara

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Melanocortin-1 Receptor Gene Variants Determine the Risk of Nonmelanoma Skin Cancer Independently of Fair Skin and Red Hair von Bastiaens, Maarten T., Huurne, Jeannet A. C. ter, Kielich, Christine, Gruis, Nelleke A., Westendorp, Rudi G.J., Vermeer, Bert Jan, Bavinck, Jan Nico Bouwes

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Excess Cancer Mortality in Six Dutch Pedigrees with the Familial Atypical Multiple Mole-Melanoma Syndrome from 1830 to 1994 von Hille, Elysée T.M., van Duijn, Erik, Gruis, Nelleke A., Rosendaal, Frits R., Bergman, Wilma, Vandenbroucke, Jan P.

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Risk of cutaneous malignant melanoma in patients with nonfamilial atypical nevi from a pigmented lesions clinic von Snels, Dyon G.C.T.M., Hille, Elysée T.M., Gruis, Nelleke A., Bergman, Wilma

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Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression von Gruis, NA, Weaver-Feldhaus, J, Liu, Q, Frye, C, Eeles, R, Orlow, I, Lacombe, L, Ponce- Castaneda, V, Lianes, P, Latres, E

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Variation in Precursor Lesions of Pancreatic Cancer among High-Risk Groups von POTJER, Thomas P, SCHOT, Ingrid, BARGELLO, Mathias, GRESS, Thomas M, VASEN, Hans F. A, BARTSCH, Detlef K, LANGER, Peter, HEVERHAGEN, Johannes T, WASSER, Martin N. J. M, SLATER, Emily P, KLÖPPEL, Gunter, MORREAU, Hans M, BONSING, Bert A, DE VOS TOT NEDERVEEN CAPPEL, Wouter H

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Melanocortin-1 Receptor Variant R151C Modifies Melanoma Risk in Dutch Families with Melanoma von van der Velden, Pieter A., Sandkuijl, Lodewijk A., Bergman, Wilma, Pavel, Stan, van Mourik, Leny, Frants, Rune R., Gruis, Nelleke A.

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CDKN2 explains part of the clinical phenotype in Dutch familial atypical multiple-mole melanoma (FAMMM) syndrome families von Gruis, N A, Sandkuijl, L A, van der Velden, P A, Bergman, W, Frants, R R

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PCR-based microsatellite polymorphisms in the detection of loss of heterozygosity in fresh and archival tumour tissue von GRUIS, N. A, ABELN, E. C. A, BARDOEL, A. F. J, DEVILEE, P, FRANTS, R. R, CORNELISSE, C. J

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Characterization of Melanocortin-1 Receptor Gene Variants in Uveal Melanoma Patients von Metzelaar-Blok, Jessica A. W, ter Huurne, Jeanet A. C, Hurks, H. Monique H, Keunen, Jan E. E, Jager, Martine J, Gruis, Nelleke A

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