GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi von Vader, M J C, Madigan, M C, Versluis, M, Suleiman, H M, Gezgin, G, Gruis, N A, Out-Luiting, J J, Bergman, W, Verdijk, R M, Jager, M J, van der Velden, P A

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Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS von Zuidervaart, W, van Nieuwpoort, F, Stark, M, Dijkman, R, Packer, L, Borgstein, A-M, Pavey, S, van der Velden, P, Out, C, Jager, M J, Hayward, N K, Gruis, N A

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MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M‐SKIP project von Stefanaki, I., Stratigos, A.J., Kypreou, K.P., Evangelou, E., Gandini, S., Maisonneuve, P., Polsky, D., Lazovich, D., Newton‐Bishop, J., Kanetsky, P.A., Puig, S., Gruis, N.A., Ghiorzo, P., Pellegrini, C., De Nicolo, A., Ribas, G., Guida, G., Garcia‐Borron, J.C., Fargnoli, M.C., Nan, H., Landi, M.T., Little, J., Sera, F., Raimondi, S.

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Association of MC1R Variants and Host Phenotypes With Melanoma Risk in CDKN2A Mutation Carriers: A GenoMEL Study von Demenais, F., Mohamdi, H., Chaudru, V., Goldstein, A. M., Newton Bishop, J. A., Bishop, D. T., Kanetsky, P. A., Hayward, N. K., Gillanders, E., Elder, D. E., Avril, M. F., Azizi, E., van Belle, P., Bergman, W., Bianchi-Scarrà, G., Bressac-de Paillerets, B., Calista, D., Carrera, C., Hansson, J., Harland, M., Hogg, D., Höiom, V., Holland, E. A., Ingvar, C., Landi, M. T., Lang, J. M., Mackie, R. M., Mann, G. J., Ming, M. E., Njauw, C. J., Olsson, H., Palmer, J., Pastorino, L., Puig, S., Randerson-Moor, J., Stark, M., Tsao, H., Tucker, M. A., van der Velden, P., Yang, X. R., Gruis, N.

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Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden) von VASEN, H. F. A, GRUIS, N. A, FRANTS, R. R, VAN DER VELDEN, P. A, HILLE, E. T. M, BERGMAN, W

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A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types von Kamb, Alexander, Gruis, Nelleke A., Weaver-Feldhaus, Jane, Liu, Qingyun, Harshman, Keith, Tavtigian, Sean V., Stockert, Elisabeth, Day, Rufus S., Johnson, Bruce E., Skolnick, Mark H.

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Cutaneous melanoma: Medical specialists' opinions on follow-up and sentinel lymph node biopsy von Wevers, K.P, Hoekstra-Weebers, J.E.H.M, Speijers, M.J, Bergman, W, Gruis, N.A, Hoekstra, H.J

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Assessing a single SNP located at TERT/CLPTM1L multi-cancer risk region as a genetic modifier for risk of pancreatic cancer and melanoma in Dutch CDKN2A mutation carriers von Christodoulou, E., Visser, M., Potjer, T. P., van der Stoep, N., Rodríguez-Girondo, M., van Doorn, R., Gruis, N.

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MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project von Tagliabue, Elena, Gandini, Sara, Bellocco, Rino, Maisonneuve, Patrick, Newton-Bishop, Julia, Polsky, David, Lazovich, DeAnn, Kanetsky, Peter A, Ghiorzo, Paola, Gruis, Nelleke A, Landi, Maria Teresa, Menin, Chiara, Fargnoli, Maria Concetta, García-Borrón, Jose Carlos, Han, Jiali, Little, Julian, Sera, Francesco, Raimondi, Sara

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Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus von Kamb, A., Shattuck-Eidens, D., Eeles, R., Liu, Q., Gruis, N. A., Ding, W., Hussey, C., Tran, T., Miki, Y., Weaver-Feldhaus, J., McClure, M., Aitken, J. F., Anderson, D. E., Bergman, W., Frants, R., Goldgar, D. E., Green, A., MacLennan, R., Martin, N. G., Meyer, L. J., Youl, P., Zone, J. J., Skolnick, M. H., Cannon-Albright, L. A.

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Gene expression profiling identifies tumour markers potentially playing a role in uveal melanoma development von Zuidervaart, W, van der Velden, P A, Hurks, M H, van Nieuwpoort, F A, Out-Luiting, C J J, Singh, A D, Frants, R R, Jager, M J, Gruis, N A

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Episodic Src activation in uveal melanoma revealed by kinase activity profiling von Maat, W, Filali, M el, Mulder, A Dirks, Luyten, G P M, Gruis, N A, Desjardins, L, Boender, P, Jager, M J, van der Velden, P A

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Melanocortin-1 Receptor Gene Variants Determine the Risk of Nonmelanoma Skin Cancer Independently of Fair Skin and Red Hair von Bastiaens, Maarten T., Huurne, Jeannet A. C. ter, Kielich, Christine, Gruis, Nelleke A., Westendorp, Rudi G.J., Vermeer, Bert Jan, Bavinck, Jan Nico Bouwes

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Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds von Gruis, Nelleke A., van der Velden, Pieter A., Sandkuijl, Lodewijk A., Prins, Duncan E., Weaver-Feldhaus, Jane, Kamb, Alexander, Bergman, Wilma, Frants, Rune R.

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Melanocortin-1 Receptor Variant R151C Modifies Melanoma Risk in Dutch Families with Melanoma von van der Velden, Pieter A., Sandkuijl, Lodewijk A., Bergman, Wilma, Pavel, Stan, van Mourik, Leny, Frants, Rune R., Gruis, Nelleke A.

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Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls von Chang, Yu-mei, Barrett, Jennifer H, Bishop, D Timothy, Armstrong, Bruce K, Bataille, Veronique, Bergman, Wilma, Berwick, Marianne, Bracci, Paige M, Elwood, J Mark, Ernstoff, Marc S, Gallagher, Richard P, Green, Adèle C, Gruis, Nelleke A, Holly, Elizabeth A, Ingvar, Christian, Kanetsky, Peter A, Karagas, Margaret R, Lee, Tim K, Le Marchand, Loïc, Mackie, Rona M, Olsson, Håkan, Østerlind, Anne, Rebbeck, Timothy R, Sasieni, Peter, Siskind, Victor, Swerdlow, Anthony J, Titus-Ernstoff, Linda, Zens, Michael S, Newton-Bishop, Julia A

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Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma von van der Velden, P A, Metzelaar-Blok, J A, Bergman, W, Monique, H, Hurks, H, Frants, R R, Gruis, N A, Jager, M J

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Variation in Precursor Lesions of Pancreatic Cancer among High-Risk Groups von POTJER, Thomas P, SCHOT, Ingrid, BARGELLO, Mathias, GRESS, Thomas M, VASEN, Hans F. A, BARTSCH, Detlef K, LANGER, Peter, HEVERHAGEN, Johannes T, WASSER, Martin N. J. M, SLATER, Emily P, KLÖPPEL, Gunter, MORREAU, Hans M, BONSING, Bert A, DE VOS TOT NEDERVEEN CAPPEL, Wouter H

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Infrequent CDKN2 (MTS1/p16) gene alterations in human primary breast cancer von BERNS, E. M. J. J, KLIJN, J. G. M, SMID, M, VAN STAVEREN, I. L, GRUIS, N. A, FOEKENS, J. A

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Germline Mutations of the CDKN2 Gene in UK Melanoma Families von Harland, Mark, Meloni, Rolando, Gruis, Nelleke, Pinney, Elizabeth, Brookes, Sharon, Spurr, Nigel K., Frischauf, Anna-Marie, Bataille, Veronique, Peters, Gordon, Cuzick, Jack, Selby, Peter, Bishop, D. Timothy, Bishop, Julia Newton

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