TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling von Grütter, Markus G, Luban, Jeremy

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Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors von Sennhauser, Gaby, Amstutz, Patrick, Briand, Christophe, Storchenegger, Otso, Grütter, Markus G

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New concepts and aids to facilitate crystallization von Bukowska, Magdalena A, Grütter, Markus G

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Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism von Bourquin, Florence, Riezman, Howard, Capitani, Guido, Grütter, Markus G.

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HIV-1 protease inhibition potential of functionalized polyoxometalates von Flütsch, Andreas, Schroeder, Thilo, Grütter, Markus G., Patzke, Greta R.

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Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor von Ravn, Peter, Madhurantakam, Chaithanya, Kunze, Susan, Matthews, Evelyn, Priest, Claire, O'Brien, Siobhan, Collinson, Andie, Papworth, Monika, Fritsch-Fredin, Maria, Jermutus, Lutz, Benthem, Lambertus, Gruetter, Markus, Jackson, Ronald H.

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TRIM5 is an innate immune sensor for the retrovirus capsid lattice von Pertel, Thomas, Hausmann, Stéphane, Morger, Damien, Züger, Sara, Guerra, Jessica, Lascano, Josefina, Reinhard, Christian, Santoni, Federico A., Uchil, Pradeep D., Chatel, Laurence, Bisiaux, Aurélie, Albert, Matthew L., Strambio-De-Castillia, Caterina, Mothes, Walther, Pizzato, Massimo, Grütter, Markus G., Luban, Jeremy

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Structural Modification of the P2‘ Position of 2,7-Dialkyl-Substituted 5(S)-Amino-4(S)-hydroxy-8-phenyl-octanecarboxamides:  The Discovery of Aliskiren, a Potent Nonpeptide Human R... von Maibaum, Jürgen, Stutz, Stefan, Göschke, Richard, Rigollier, Pascal, Yamaguchi, Yasuchika, Cumin, Frédéric, Rahuel, Joseph, Baum, Hans-Peter, Cohen, Nissim-Claude, Schnell, Christian R, Fuhrer, Walter, Gruetter, Markus G, Schilling, Walter, Wood, Jeanette M

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Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB von Gut, Heinz, Pennacchietti, Eugenia, John, Robert A, Bossa, Francesco, Capitani, Guido, De Biase, Daniela, Grütter, Markus G

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Specific Inhibition of Caspase-3 by a Competitive DARPin: Molecular Mimicry between Native and Designed Inhibitors von Schroeder, Thilo, Barandun, Jonas, Flütsch, Andreas, Briand, Christophe, Mittl, Peer R.E., Grütter, Markus G.

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Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter CitS Revealed by Electron Crystallography von Kebbel, Fabian, Kurz, Mareike, Arheit, Marcel, Grütter, Markus G., Stahlberg, Henning

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cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions von Grütter, Christian, Wilkinson, Trevor, Turner, Richard, Podichetty, Sadhana, Finch, Donna, McCourt, Matthew, Loning, Scott, Jermutus, Lutz, Grütter, Markus G

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High-throughput counter-diffusion capillary crystallization and in situ diffraction using high-pressure freezing in protein crystallography von Kurz, Mareike, Blattmann, Beat, Kaech, Andres, Briand, Christophe, Reardon, Paul, Ziegler, Urs, Gruetter, Markus G.

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Structural and functional insights into the assembly of type 1 pili from Escherichia coli von Capitani, Guido, Eidam, Oliv, Glockshuber, Rudi, Grütter, Markus G.

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Structural genomics: Open collaboration is key to new drugs von Gruetter, Markus

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Open collaboration is key to new drugs von Gruetter, Markus

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Novel 2,7-Dialkyl-Substituted 5(S)-Amino-4(S)-hydroxy-8-phenyl-octanecarboxamide Transition State Peptidomimetics Are Potent and Orally Active Inhibitors of Human Renin von Göschke, Richard, Stutz, Stefan, Rasetti, Vittorio, Cohen, Nissim-Claude, Rahuel, Joseph, Rigollier, Pascal, Baum, Hans-Peter, Forgiarini, Peter, Schnell, Christian R, Wagner, Trixie, Gruetter, Markus G, Fuhrer, Walter, Schilling, Walter, Cumin, Frédéric, Wood, Jeanette M, Maibaum, Jürgen

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Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation von Hohl, Michael, Briand, Christophe, Grütter, Markus G, Seeger, Markus A

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Precision is essential for efficient catalysis in an evolved Kemp eliminase von Blomberg, Rebecca, Kries, Hajo, Pinkas, Daniel M., Mittl, Peer R. E., Grütter, Markus G., Privett, Heidi K., Mayo, Stephen L., Hilvert, Donald

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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 von Spalinger, Marianne R, Kasper, Stephanie, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Vavricka, Stephan R, Scharl, Sylvie, Raselli, Tina, Frey-Wagner, Isabelle, Gutte, Petrus M, Grütter, Markus G, Beer, Hans-Dietmar, Contassot, Emmanuel, Chan, Andrew C, Dai, Xuezhi, Rawlings, David J, Mair, Florian, Becher, Burkhard, Falk, Werner, Fried, Michael, Rogler, Gerhard, Scharl, Michael

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