The FTMap family of web servers for determining and characterizing ligand-binding hot spots of proteins von Kozakov, Dima, Grove, Laurie E, Hall, David R, Bohnuud, Tanggis, Mottarella, Scott E, Luo, Lingqi, Xia, Bing, Beglov, Dmitri, Vajda, Sandor

Volltext

Structural conservation of druggable hot spots in protein–protein interfaces von Kozakov, Dima, Hall, David R, Chuang, Gwo-Yu, Cencic, Regina, Brenke, Ryan, Grove, Laurie E, Beglov, Dmitri, Pelletier, Jerry, Whitty, Adrian, Vajda, Sandor

Volltext

Safety and efficacy of brentuximab vedotin for Hodgkin lymphoma recurring after allogeneic stem cell transplantation von Gopal, Ajay K., Ramchandren, Radhakrishnan, O'Connor, Owen A., Berryman, Robert B., Advani, Ranjana H., Chen, Robert, Smith, Scott E., Cooper, Maureen, Rothe, Achim, Matous, Jeffrey V., Grove, Laurie E., Zain, Jasmine

Volltext

Randomized, phase IIb study of low-dose cytarabine and lintuzumab versus low-dose cytarabine and placebo in older adults with untreated acute myeloid leukemia von Sekeres, Mikkael A, Lancet, Jeffrey E, Wood, Brent L, Grove, Laurie E, Sandalic, Larissa, Sievers, Eric L, Jurcic, Joseph G

Volltext

FTSite: high accuracy detection of ligand binding sites on unbound protein structures von Ngan, Chi-Ho, Hall, David R, Zerbe, Brandon, Grove, Laurie E, Kozakov, Dima, Vajda, Sandor

Volltext

FTFlex: accounting for binding site flexibility to improve fragment-based identification of druggable hot spots von Grove, Laurie E, Hall, David R, Beglov, Dmitri, Vajda, Sandor, Kozakov, Dima

Volltext

CYP3A-Mediated Drug-Drug Interaction Potential and Excretion of Brentuximab Vedotin, an Antibody−Drug Conjugate, in Patients With CD30-Positive Hematologic Malignancies von Han, Tae H., Gopal, Ajay K., Ramchandren, Radhakrishnan, Goy, Andre, Chen, Robert, Matous, Jeffrey V., Cooper, Maureen, Grove, Laurie E., Alley, Stephen C., Lynch, Carmel M., O'Connor, Owen A.

Volltext

Robust Identification of Binding Hot Spots Using Continuum Electrostatics: Application to Hen Egg-White Lysozyme von Hall, David H, Grove, Laurie E, Yueh, Christine, Ngan, Chi Ho, Kozakov, Dima, Vajda, Sandor

Volltext

Focused grid-based resampling for protein docking and mapping von Mamonov, Artem B., Moghadasi, Mohammad, Mirzaei, Hanieh, Zarbafian, Shahrooz, Grove, Laurie E., Bohnuud, Tanggis, Vakili, Pirooz, Ch. Paschalidis, Ioannis, Vajda, Sandor, Kozakov, Dima

Volltext

Spectroscopic and Computational Investigation of Second-Sphere Contributions to Redox Tuning in Escherichia coli Iron Superoxide Dismutase von Grove, Laurie E, Xie, Juan, Yikilmaz, Emine, Miller, Anne-Frances, Brunold, Thomas C

Volltext

Kinetic and Computational Investigations into the Origin of Metal‐Ion Specificity in Matrix Metalloproteinase‐1 von Grove, Laurie E., Palladini, Jacob

Volltext

How Can a Single Second Sphere Amino Acid Substitution Cause Reduction Midpoint Potential Changes of Hundreds of Millivolts? von Yikilmaz, Emine, Porta, Jason, Grove, Laurie E, Vahedi-Faridi, Ardeschir, Bronshteyn, Yuriy, Brunold, Thomas C, Borgstahl, Gloria E. O, Miller, Anne-Frances

Volltext

Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial von Raza, Azra, Jurcic, Joseph G., Roboz, Gail J., Maris, Michael, Stephenson, Joseph J., Wood, Brent L., Feldman, Eric J., Galili, Naomi, Grove, Laurie E., Drachman, Jonathan G., Sievers, Eric L.

Volltext

Spectroscopic and Computational Insights into Second-Sphere Amino-Acid Tuning of Substrate Analogue/Active-Site Interactions in Iron(III) Superoxide Dismutase von Grove, Laurie E, Xie, Juan, Yikilmaz, Emine, Karapetyan, Anush, Miller, Anne-Frances, Brunold, Thomas C

Volltext

Synthesis, X-Ray Crystallographic Characterization, and Electronic Structure Studies of a Di-Azide Iron(III) Complex: Implications for the Azide Adducts of Iron(III) Superoxide Dis... von Grove, Laurie E, Hallman, Jason K, Emerson, Joseph P, Halfen, Jason A, Brunold, Thomas C

Volltext

A randomized, multicenter study to determine the safety and efficacy of the immunoconjugate SGN-15 plus docetaxel for the treatment of non-small cell lung carcinoma von Ross, Helen J., Hart, Lowell L., Swanson, Paul M., Rarick, Mark U., Figlin, Robert A., Jacobs, Andrew D., McCune, David E., Rosenberg, Arthur H., Baron, Ari D., Grove, Laurie E., Thorn, Michael D., Miller, Dennis M., Drachman, Jonathan G., Rudin, Charles M.

Volltext

Carbon–sulfur bond cleavage and reduction of thiols and dithioethers under oxidative conditions von Remias, Joseph E., Grove, Laurie E., Sen, Ayusman

Volltext

Brentuximab vedotin for relapsed or refractory non-Hodgkin lymphoma: Preliminary results from a phase II study von Advani, Ranjana, Oki, Yasuhiro, Shustov, Andrei R., Grove, Laurie E., Bartlett, Nancy

Volltext

Lintuzumab and Low-Dose Cytarabine Compared to Placebo and Low-Dose Cytarabine in Patients with Untreated Acute Myeloid Leukemia (AML) 60 Years and Older: Results of a Randomized,... von Lancet, Jeffrey E., Sekeres, Mikkael A., Wood, Brent L., Grove, Laurie E., Sandalic, Larissa, Sievers, Eric L., Jurcic, Joseph G.

Volltext

Retreatment with brentuximab vedotin in CD30‑positive hematologic malignancies: A phase II study von Bartlett, Nancy, Brice, Pauline, Chen, Robert W., Fanale, Michelle A., Gopal, Ajay K., Matous, Jeffrey, Rosenblatt, Joseph David, Grove, Laurie E., Forero-Torres, Andres

Volltext