P-62 Characterization and management of cholangiocarcinoma in a tertiary hospital with a high volume of patients von Gallego Jimenez, I., Garcia Grove, C., Tallafigo, F., Limon, L.

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P-68 Response to neoadjuvant chemotherapy in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma with FLOT-regimen in our setting von Garcia Grove, C., Gallego Jimenez, I., Martinez Bernal, G., Miras Rodriguez, I., Limón Miron, M.

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P-66 Experience in our center of bone events not related to the disease in patients with locally advanced or metastatic adenocarcinoma of the pancreas von Gallego Jimenez, I., Martinez Bernal, G., Garcia Grove, C., Tallafigo, F., Limón Miron, M.

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454P Tetrahydrocannabinol (THC) / cannabidiol (CBD) oral solution in combination with temozolomide (TMZ) and radiotherapy (RT) in patients with newly diagnosed glioblastoma: Phase... von Sepúlveda, J.M., Alonso, M., Velilla, G., Grove, C. Garcia, Martínez-García, M., Foro, P., Gonzalez, C. Garcia, Lopez, C. Muriel, Luque, R., Luque, N., Stradella, A., Viltró, P. Sàbat, Martín, M. Navarro, López, B. Rivas, Guzmán, M., Tovar-Ambel, E., Velasco, G., Morillas, R. Sanchez, Salva, J. Fuster

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P-138 Retrospective analysis of management of BRAF V600E mutated colorectal cancer in a single institution von Velasco, R. Pérez, Rodríguez, P. Macías, Grove, C. Garcia, Sánchez, D. Martín, Torrado, C., Barroso, A., Tallafigo, F., Monescillo, E., Pérez, R. Buezas, Sempere, J. Torres, Vicente, A. Pereira, Valladares-Ayerbes, M., Ladrón, A. López, Rodriguez, J., Limon, L., Jimenez, I. Gallego

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Middle-range theories of land system change von Meyfroidt, P., Roy Chowdhury, R., de Bremond, A., Ellis, E.C., Erb, K.-H., Filatova, T., Garrett, R.D., Grove, J.M., Heinimann, A., Kuemmerle, T., Kull, C.A., Lambin, E.F., Landon, Y., le Polain de Waroux, Y., Messerli, P., Müller, D., Nielsen, J.Ø., Peterson, G.D., Rodriguez García, V., Schlüter, M., Turner, B.L., Verburg, P.H.

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Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) von Chen, Guo-Chong, Chai, Jin Choul, Yu, Bing, Michelotti, Gregory A, Grove, Megan L, Fretts, Amanda M, Daviglus, Martha L, Garcia-Bedoya, Olga L, Thyagarajan, Bharat, Schneiderman, Neil, Cai, Jianwen, Kaplan, Robert C, Boerwinkle, Eric, Qi, Qibin

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Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet von Lucena, M.I., Villanueva-Paz, M., Alvarez-Alvarez, I., Aithal, G.P., Björnsson, E.S., Cakan-Akdogan, G., Cubero, F.J., Esteves, F., Falcon-Perez, J.M., Fromenty, B., Garcia-Ruiz, C., Grove, J.I., Konu, O., Kranendonk, M., Kullak-Ublick, G.A., Miranda, J.P., Remesal-Doblado, A., Sancho-Bru, P., Nelson, L., Andrade, R.J., Daly, A.K., Fernandez-Checa, J.C.

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The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis von Cowley, Michael A, Smith, Roy G, Diano, Sabrina, Tschöp, Matthias, Pronchuk, Nina, Grove, Kevin L, Strasburger, Christian J, Bidlingmaier, Martin, Esterman, Michael, Heiman, Mark L, Garcia-Segura, Luis Miguel, Nillni, Eduardo A, Mendez, Pablo, Low, Malcolm J, Sotonyi, Peter, Friedman, Jeffrey M, Liu, Hongyan, Pinto, Shirly, Colmers, William F, Cone, Roger D, Horvath, Tamas L

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Negotiating local versus global needs in the International Long Term Ecological Research Network's socio-ecological research agenda von Holzer, J M, Adamescu, M C, Bonet-García, F J, Díaz-Delgado, R, Dick, J, Grove, J M, Rozzi, R, Orenstein, D E

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Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women von Fox, Caroline S, Liu, Yongmei, White, Charles C, Feitosa, Mary, Smith, Albert V, Heard-Costa, Nancy, Lohman, Kurt, Johnson, Andrew D, Foster, Meredith C, Greenawalt, Danielle M, Griffin, Paula, Ding, Jinghong, Newman, Anne B, Tylavsky, Fran, Miljkovic, Iva, Kritchevsky, Stephen B, Launer, Lenore, Garcia, Melissa, Eiriksdottir, Gudny, Carr, J Jeffrey, Gudnason, Vilmunder, Harris, Tamara B, Cupples, L Adrienne, Borecki, Ingrid B

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Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood von Kariotis, Sokratis, Jammeh, Emmanuel, Swietlik, Emilia M., Pickworth, Josephine A., Rhodes, Christopher J., Otero, Pablo, Wharton, John, Iremonger, James, Dunning, Mark J., Pandya, Divya, Mascarenhas, Thomas S., Errington, Niamh, Thompson, A. A. Roger, Romanoski, Casey E., Rischard, Franz, Garcia, Joe G. N., Yuan, Jason X.-J., An, Tae-Hwi Schwantes, Desai, Ankit A., Coghlan, Gerry, Lordan, Jim, Corris, Paul A., Howard, Luke S., Condliffe, Robin, Kiely, David G., Church, Colin, Pepke-Zaba, Joanna, Toshner, Mark, Wort, Stephen, Gräf, Stefan, Morrell, Nicholas W., Wilkins, Martin R., Lawrie, Allan, Wang, Dennis

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PLD3 variants in population studies von van der Lee, Sven J., Holstege, Henne, Wong, Tsz Hang, Jakobsdottir, Johanna, Bis, Joshua C., Chouraki, Vincent, van Rooij, Jeroen G. J., Grove, Megan L., Smith, Albert V., Amin, Najaf, Choi, Seung-Hoan, Beiser, Alexa S., Garcia, Melissa E., van IJcken, Wilfred F. J., Pijnenburg, Yolande A. L., Louwersheimer, Eva, Brouwer, Rutger W. W., van den Hout, Mirjam C. G. N., Oole, Edwin, Eirkisdottir, Gudny, Levy, Daniel, Rotter, Jerome I., Emilsson, Valur, O'Donnell, Christopher J., Aspelund, Thor, Uitterlinden, Andre G., Launer, Lenore J., Hofman, Albert, Boerwinkle, Eric, Psaty, Bruce M., DeStefano, Anita L., Scheltens, Philip, Seshadri, Sudha, van Swieten, John C., Gudnason, Vilmundur, van der Flier, Wiesje M., Ikram, M. Arfan, van Duijn, Cornelia M.

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Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti von Hallett, T B, Aberle-Grasse, J, Bello, G, Boulos, L-M, Cayemittes, M P A, Cheluget, B, Chipeta, J, Dorrington, R, Dube, S, Ekra, A K, Garcia-Calleja, J M, Garnett, G P, Greby, S, Gregson, S, Grove, J T, Hader, S, Hanson, J, Hladik, W, Ismail, S, Kassim, S, Kirungi, W, Kouassi, L, Mahomva, A, Marum, L, Maurice, C, Nolan, M, Rehle, T, Stover, J, Walker, N

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Sex differences in the effects of sleep restriction and scheduled short naps on vigilance, cognition and sleep architecture in healthy elderly adults von Michalak, A., Shabana, Z., Garcia Vite, T., Grove, V., Mann, A., Conway, T., Dietrich, C., Tsigarides, J., Gill, N., Hornberger, M., Lazar, A.S.

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Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women von Jones, Garan, Trajanoska, Katerina, Santanasto, Adam J., Stringa, Najada, Kuo, Chia-Ling, Atkins, Janice L., Lewis, Joshua R., Duong, ThuyVy, Hong, Shengjun, Biggs, Mary L., Luan, Jian’an, Sarnowski, Chloe, Lunetta, Kathryn L., Tanaka, Toshiko, Wojczynski, Mary K., Cvejkus, Ryan, Nethander, Maria, Ghasemi, Sahar, Yang, Jingyun, Zillikens, M. Carola, Walter, Stefan, Sicinski, Kamil, Kague, Erika, Ackert-Bicknell, Cheryl L., Arking, Dan E., Windham, B. Gwen, Boerwinkle, Eric, Grove, Megan L., Graff, Misa, Spira, Dominik, Demuth, Ilja, van der Velde, Nathalie, de Groot, Lisette C. P. G. M., Psaty, Bruce M., Odden, Michelle C., Fohner, Alison E., Langenberg, Claudia, Wareham, Nicholas J., Bandinelli, Stefania, van Schoor, Natasja M., Huisman, Martijn, Tan, Qihua, Zmuda, Joseph, Mellström, Dan, Karlsson, Magnus, Bennett, David A., Buchman, Aron S., De Jager, Philip L., Uitterlinden, Andre G., Völker, Uwe, Kocher, Thomas, Teumer, Alexander, Rodriguéz-Mañas, Leocadio, García, Francisco J., Carnicero, José A., Herd, Pamela, Bertram, Lars, Ohlsson, Claes, Murabito, Joanne M., Melzer, David, Kuchel, George A., Ferrucci, Luigi, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas P., Pilling, Luke C.

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Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet von Lucena, M I, Villanueva-Paz, M, Alvarez-Alvarez, I, Aithal, G P, Björnsson, E S, Cakan-Akdogan, G, Cubero, F J, Esteves, F, Falcon-Perez, J M, Fromenty, B, Garcia-Ruiz, C, Grove, J I, Konu, O, Kranendonk, M, Kullak-Ublick, G A, Miranda, J P, Remesal-Doblado, A, Sancho-Bru, P, Nelson, L, Andrade, R J, Daly, A K, Fernandez-Checa, J C

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α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors von Enriori, Pablo J, Chen, Weiyi, Garcia-Rudaz, Maria C, Grayson, Bernadette E, Evans, Anne E, Comstock, Sarah M, Gebhardt, Ursel, Müller, Hermann L, Reinehr, Thomas, Henry, Belinda A, Brown, Russell D, Bruce, Clinton R, Simonds, Stephanie E, Litwak, Sara A, McGee, Sean L, Luquet, Serge, Martinez, Sarah, Jastroch, Martin, Tschöp, Matthias H, Watt, Matthew J, Clarke, Iain J, Roth, Christian L, Grove, Kevin L, Cowley, Michael A

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Long-term impact of behavioral weight loss intervention on cognitive function von Espeland, Mark A, Rapp, Stephen R, Bray, George A, Houston, Denise K, Johnson, Karen C, Kitabchi, Abbas E, Hergenroeder, Andrea L, Williamson, Jeff, Jakicic, John M, van Dorsten, Brent, Kritchevsky, Stephen B

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Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood von Kariotis, S, Jammeh, E, Swietlik, EM, Pickworth, JA, Rhodes, CJ, Wharton, J, Iremonger, J, Dunning, MJ, Pandya, D, Mascarenhas, TS, Errington, N, Thompson, AAR, Romanoski, CE, Rischard, F, Garcia, JGN, Yuan, JX-J, An, T-HS, Desai, AA, Coghlan, G, Lordan, J, Corris, PA, Howard, LS, Condliffe, R, Kiely, DG, Church, C, Pepke-Zaba, J, Toshner, M, Wort, S, Graf, S, Morrell, NW, Wilkins, MR, Lawrie, A, Wang, D, Bleda, M, Hadinnapola, C, Haimel, M, Auckland, K, Tilly, T, Martin, JM, Yates, K, Treacy, CM, Day, M, Greenhalgh, A, Shipley, D, Peacock, AJ, Irvine, V, Kennedy, F, Moledina, S, MacDonald, L, Tamvaki, E, Barnes, A, Cookson, V, Chentouf, L, Ali, S, Othman, S, Ranganathan, L, Gibbs, JSR, DaCosta, R, Pinguel, J, Dormand, N, Parker, A, Stokes, D, Ghedia, D, Tan, Y, Ngcozana, T, Wanjiku, I, Polwarth, G, Mackenzie Ross, RV, Suntharalingam, J, Grover, M, Kirby, A, Grove, A, White, K, Seatter, A, Creaser-Myers, A, Walker, S, Roney, S, Elliot, CA, Charalampopoulos, A, Sabroe, I, Hameed, A, Armstrong, I, Hamilton, N, Rothman, AMK, Swift, AJ, Wild, JM, Soubrier, F, Eyries, M, Humbert, M, Montani, D, Girerd, B, Scelsi, L, Ghio, S, Gall, H, Ghofrani, A, Bogaard, HJ, Noordegraaf, AV, Houweling, AC, Veld, AHI, Schotte, G

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