1003P A first-in-human (FIH) phase I study of IPH5301, an anti-CD73 monoclonal antibody (mAb), in patients with advanced solid tumors (AST) (CHANCES, NCT05143970) von Beaufils, M., Mailliez, A., Sfumato, P., Vicier, C., Provansal Gross, M., Guerin, M., Chanez, B., Kotecki, N., Widemann, A., Panzolato, S., Boyer Chammard, A., André, P., Paturel, C.L., Gouarne, C., Awada, A.H., Boher, J.M., Gonçalves, A.

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711O Avelumab + methotrexate to eradicate low-risk gestational trophoblastic tumors in first-line setting: TROPHAMET phase I/II trial von You, B., Lotz, J-P., Descargues, P., Lobbedez, F. Joly, De La Motte Rouge, T., Lebreton, C., Gladieff, L., Follana, P., Jamelot, M., Massardier, J., Hajri, T., Alves-Ferreira, M., Bin, S., Langlois-Jacques, C., Bonjour, M., Roux, A., Desauw, C., Gross, M. Provansal, Golfier, F., Bolze, P-A.

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528MO Is re-introduction or continuation of PARP inhibitors after local therapy for oligo-metastatic progression in patients with relapsed ovarian cancer relevant? von Thibault, G., Kfoury, M., Lorusso, D., Floquet, A., Ventriglia, J., Salaun, H., Moubarak, M., Rivoirard, R., Polastro, L., Favier, L., You, B., Berton-Rigaud, D., De La Motte Rouge, T., Mansi, L., Abdeddaim, C., Prulhiere, K., Lancry Lecomte, L., Provansal Gross, M., Dalban, C., Ray-Coquard, I.L.

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535P Long term quality of life after chemotherapy among nonepithelial ovarian cancer survivors: The case-control vivrovaire rare tumours study von Joly Lobbedez, F., Ray-Coquard, I.L., Lefevre Arbogast, S., Grellard, J-M., Clarisse, B., Floquet, A., Selle, F., Berton-Rigaud, D., Frank, S., De La Motte Rouge, T., Kalbacher, E., Provansal Gross, M., A. lortholary, Orfeuvre, H., Alexandre, J., Augereau, P., Kurtz, J.E., Nadeau, C., Pautier, P., Gernier, F.

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22P Predictive value of tertiary lymphoid structure in patients with mismatch repair deficient advanced/recurrent endometrial cancer treated with dostarlimab von Kfoury, M., Pesce, F., Provansal Gross, M., Charafe, E., Gorvel, L., Rousseau, F., Cappiello, M.A., Sabatier, R.

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746P Real-world clinical outcomes of patients with de novo advanced high-grade epithelial ovarian cancer eligible to niraparib maintenance in France von Rodrigues, M., Joly, F., Ray-Coquard, I.L., Costaz, H., Classe, J-M., Floquet, A., De La Motte Rouge, T., Colombo, P-E., Gross, M. Provansal, Leblanc, E., Pomel, C., Marchal, F., Barranger, E., Savoye, A.M., Guillemet, C., Petit, T., Pautier, P., Rouzier, R., Courtinard, C., Gladieff, L.

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817TiP GYNET study - Safety and efficacy of anti-netrin 1 (NP137) in combination with chemotherapy and/or pembrolizumab in patients (pts) with pretreated locally advanced/metastati... von Ray-Coquard, I., Cassier, P., Chabaud, S., Mehlen, P., Bernet, A., Le Bras, F., Gheit, H., Angel, C., Mastier, C., Ducarouge, B., De La Motte Rouge, T., Gladieff, L., Floquet, A., Fabbro, M., Joly, F., Provansal Gross, M., Frenel, J-S., Leary, A., Perol, D., Blay, J-Y.

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808MO Paclitaxel with or without pazopanib in ovarian cancer patients with relapse during bevacizumab maintenance therapy: The GINECO randomized phase II TAPAZ study von Joly Lobbedez, F., Fabbro, M., Berton, D., Lequesne, J., Anota, A., Puszkiel, A., Floquet, A., Cancel, M., Bourgeois, H., Bengrine Lefevre, L., You, B., Pommeret, F., Lortholary, A., Spaeth, D., Martin-Babau, J., Abdeddaim, C., Kaminsky-Forrett, M-C., Petran, D., Provansal Gross, M., Brachet, P-E.

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829P Regorafenib (R) or tamoxifen (T) for platinum-sensitive recurrent ovarian cancer (PSROC) with rising CA125 and no evidence of clinical or radiological disease progression: A G... von Tredan, O., Provansal Gross, M., Abdeddaim, C., Chabaud, S., Anota, A., Treilleux, I., Pissaloux, D., Savoye, A.M., Hardy Bessard, A-C., Kalbacher, E., Floquet, A., Venat-Bouvet, L., Lortholary, A., Pop, O., Frenel, J-S., Cancel, M., Largillier, R., Louvet, C., Brocard, F., Ray-Coquard, I.L.

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34O ROCSAN: A multicentric randomized phase II/III evaluating dostarlimab in combination with niraparib versus niraparib alone compared to chemotherapy in the treatment of endometr... von Ray-Coquard, I.L., Bellesoeur, A., Fabbro, M., Vanacker, H., Bigot, F., Chevalier-Evain, V., Angelergues, A., Eberst, L., Kalbacher, E., Lebreton, C., Kaminsky-Forrett, M-C., Lefeuvre-Plesse, C., Deldycke, C., Berton-Rigaud, D., Gross, M. Provansal, Betrian, S., Mouret-Reynier, M-A., Treilleux, I., Demontfort, A., Leary, A.

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19P Long-term fatigue after treatments for non-epithelial ovarian cancer survivors von Dubot, C., Ray-Coquard, I.L., Pautier, P., Lequesne, J., Renaud, T., Selle, F., Berton-Rigaud, D., Frank, S., De La Motte Rouge, T., Kalbacher, E., Gross, M. Provansal, Blonz, C., Orfeuvre, H., Alexandre, J., Augereau, P., Kurtz, J.E., Grellard, J-M., Clarisse, B., Gernier, F., Lobbedez, F. Joly

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199TiP A first-in-human phase I study of IPH5301, an anti-CD73 monoclonal antibody, alone or in combination with chemotherapy and trastuzumab, in patients with advanced solid tumor... von Gonçalves, A., Vicier, C., Guerin, M., Pignon, J., Chanez, B., Provansal Gross, M., Penel, N., Kotecki, N., Marie, D.B., Boyer Chammard, A., Paturel, C.L., André, P., Pakradouni, J., Boher, J.M., Awada, F.

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19P Long term sexual disorders among rare ovarian cancer survivors: The national GINECO case-control Vivrovaire Rare Tumors study von Dubot, C., Joly Lobbedez, F., Ray Coquard, I.L., Floquet, A., Lefevre Arbogast, S., Selle, F., Berton-Rigaud, D., Frank, S., De La Motte Rouge, T., Kalbacher, E., Provansal Gross, M., Lortholary, A., Orfeuvre, H., Alexandre, J., Augereau, P., Nadeau, C., Kurtz, J.E., Grellard, J-M., Pautier, P., Gernier, F.

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13O Impact of surgery and chemotherapy in ovarian sex cord-stromal tumors from the multicentric Salomé study including 469 patients: A TMRG and GINECO group study von Hanvic, B., Lecuru, F., Vanacker, H., Pautier, P., Narducci, F., Cherifi, F., Floquet, A., Angeles, M.A., Berton-Rigaud, D., Pomel, C., Kalbacher, E., Provansal Gross, M., Fernandez, Y., De La Motte Rouge, T., Selle, F., Meeus, P., Genestie, C., Salleron, J., Ray-Coquard, I.L.

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