Model Systems in Endometriosis Research: Translation, Translation, Translation von Groothuis, Patrick

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Is it time for a paradigm shift in drug research and development in endometriosis/adenomyosis? von Guo, Sun-Wei, Groothuis, Patrick G

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The Preclinical Profile of the Duocarmycin-Based HER2-Targeting ADC SYD985 Predicts for Clinical Benefit in Low HER2-Expressing Breast Cancers von van der Lee, Miranda M C, Groothuis, Patrick G, Ubink, Ruud, van der Vleuten, Monique A J, van Achterberg, Tanja A, Loosveld, Eline M, Damming, Désirée, Jacobs, Daniëlle C H, Rouwette, Myrthe, Egging, David F, van den Dobbelsteen, Diels, Beusker, Patrick H, Goedings, Peter, Verheijden, Gijs F M, Lemmens, Jacques M, Timmers, Marco, Dokter, Wim H A

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Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones von Amos-Landgraf, James M., Heijmans, Jarom, Wielenga, Mattheus C. B., Dunkin, Elisa, Krentz, Kathy J., Clipson, Linda, Ederveen, Antwan G., Groothuis, Patrick G., Mosselman, Sietse, Muncan, Vanesa, Hommes, Daniel W., Shedlovsky, Alexandra, Dove, William F., van den Brink, Gijs R.

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Preclinical profile of the HER2-targeting ADC SYD983/SYD985: introduction of a new duocarmycin-based linker-drug platform von Dokter, Wim, Ubink, Ruud, van der Lee, Miranda, van der Vleuten, Monique, van Achterberg, Tanja, Jacobs, Danielle, Loosveld, Eline, van den Dobbelsteen, Diels, Egging, David, Mattaar, Ellen, Groothuis, Patrick, Beusker, Patrick, Coumans, Ruud, Elgersma, Ronald, Menge, Wiro, Joosten, John, Spijker, Henri, Huijbregts, Tijl, de Groot, Vincent, Eppink, Michel, de Roo, Guy, Verheijden, Gijs, Timmers, Marco

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Drug Development in Endometriosis and Adenomyosis: It Takes More Than Just Good Science von Groothuis, Patrick G., Guo, Sun-Wei

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Endometriosis is associated with aberrant metabolite profiles in plasma von Letsiou, Sophia, Ph.D, Peterse, Dirkje P., M.Sc, Fassbender, Amelie, Ph.D, Hendriks, Margriet M., Ph.D, van den Broek, Niels J., B.Sc, Berger, Rudolf, M.D, O, Dorien F., M.Sc, Vanhie, Arne, M.D, Vodolazkaia, Alexandra, M.D., Ph.D, Van Langendonckt, Anne, M.D., Ph.D, Donnez, Jacques, M.D., Ph.D, Harms, Amy C., Ph.D, Vreeken, Rob J., Ph.D, Groothuis, Patrick G., Ph.D, Dolmans, Marie-Madeleine, M.D., Ph.D, Brenkman, Arjan B., Ph.D, D'Hooghe, Thomas M., M.D., Ph.D

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A Platform for the Generation of Site-Specific Antibody–Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines von Coumans, Ruud G. E, Ariaans, Gerry J. A, Spijker, Henri J, Renart Verkerk, Pascal, Beusker, Patrick H, Kokke, Bas P. A, Schouten, Jan, Blomenröhr, Marion, van der Lee, Miranda M. C, Groothuis, Patrick G, Ubink, Ruud, Dokter, Wim H. A, Timmers, C. Marco

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Preclinical Profile of BYON3521 Predicts an Effective and Safe MET Antibody-Drug Conjugate von Groothuis, Patrick G, Jacobs, Daniëlle C H, Hermens, Inge A T, Damming, Désirée, Berentsen, Kim, Mattaar-Hepp, Ellen, Stokman, Marloes E M, Boekel, Tinie van, Rouwette, Myrthe, van der Vleuten, Monique A J, Sesink, Aloys, Dijcks, Fred A, Coumans, Ruud G E, Schouten, Jan, Glaudemans, Dirk H, Wijk, Daniëlle van, Blomenröhr, Marion, Kappers, Wendela A, Ubink, Ruud, van der Lee, Miranda M C, Dokter, Wim H A

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Deoxyribonucleic acid methyltransferases and methyl-CpG-binding domain proteins in human endometrium and endometriosis von van Kaam, Kim J.A.F., M.D, Delvoux, Bert, Romano, Andrea, Ph.D, D’Hooghe, Thomas, M.D., Ph.D, Dunselman, Gerard A.J., M.D., Ph.D, Groothuis, Patrick G., Ph.D

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Unraveling the Interaction between Carboxylesterase 1c and the Antibody-Drug Conjugate SYD985: Improved Translational PK/PD by Using Ces1c Knockout Mice von Ubink, Ruud, Dirksen, Eef H C, Rouwette, Myrthe, Bos, Ebo S, Janssen, Ingrid, Egging, David F, Loosveld, Eline M, van Achterberg, Tanja A, Berentsen, Kim, van der Lee, Miranda M C, Bichat, Francis, Raguin, Olivier, van der Vleuten, Monique A J, Groothuis, Patrick G, Dokter, Wim H A

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Antiangiogenesis Therapy for Endometriosis von Nap, Annemiek W., Griffioen, Arjan W., Dunselman, Gerard A. J., Bouma-Ter Steege, Jessica C. A., Thijssen, Victor L. J. L., Evers, Johannes L. H., Groothuis, Patrick G.

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An objective and automated method for evaluating abdominal hyperalgesia in a rat model for endometriosis von van Aken, Mieke AW, Groothuis, Patrick G, Panagiotou, Maria, Duin, Marcel van, Nap, Annemiek W, van Rijn, Tineke CM, Kozicz, Tamas, Braat, Didi DM, Peeters, Ard BWMM

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Intestinal tumorigenesis is not affected by progesterone signaling in rodent models von Heijmans, Jarom, Muncan, Vanesa, Jacobs, Rutger J, de Jonge-Muller, Eveline S M, Graven, Laura, Biemond, Izak, Ederveen, Antwan G, Groothuis, Patrick G, Mosselman, Sietse, Hardwick, James C, Hommes, Daniel W, van den Brink, Gijs R

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Correction: Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models von Heijmans, Jarom, Muncan, Vanesa, Jacobs, Rutger J, de Jonge-Muller, Eveline S M, Graven, Laura, Biemond, Izak, Ederveen, Antwan G, Groothuis, Patrick G, Mosselman, Sietse, Hardwick, James C, Hommes, Daniel W, van den Brink, Gijs R

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The PROGINS polymorphism of the human progesterone receptor diminishes the response to progesterone von Romano, Andrea, Delvoux, Bert, Fischer, Dagmar-Christiane, Groothuis, Patrick

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Role and Regulation of the Serum- and Glucocorticoid-Regulated Kinase 1 in Fertile and Infertile Human Endometrium von Feroze-Zaidi, Fakhera, Fusi, Luca, Takano, Masashi, Higham, Jenny, Salker, Madhuri S, Goto, Tomoko, Edassery, Seby, Klingel, Karin, Boini, Krishna Murthy, Palmada, Monica, Kamps, Rick, Groothuis, Patrick G, Lam, Eric W.-F, Smith, Stephen K, Lang, Florian, Sharkey, Andrew M, Brosens, Jan J

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Antiangiogenic and vascular-disrupting agents in endometriosis: pitfalls and promises von Van Langendonckt, Anne, Donnez, Jacques, Defrère, Sylvie, Dunselman, Gerard A.J., Groothuis, Patrick G.

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Angiostatic agents prevent the development of endometriosis-like lesions in the chicken chorioallantoic membrane von Nap, Annemiek W., Dunselman, Gerard A.J., Griffioen, Arjan W., Mayo, Kevin H., Evers, Johannes L.H., Groothuis, Patrick G.

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Pathogenesis of endometriosis von Nap, Annemiek W, Groothuis, Patrick G, Demir, Ayse Y, Evers, Johannes L.H, Dunselman, Gerard A.J

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