Remote digital monitoring in clinical trials in the time of COVID-19 von Goldsack, Jennifer C., Izmailova, Elena S., Menetski, Joseph P., Hoffmann, Steven C., Groenen, Peter M.A., Wagner, John A.

Volltext

A molecular view of amyotrophic lateral sclerosis through the lens of interaction network modules von Jensen, Klaus Højgaard, Stalder, Anna Katharina, Wernersson, Rasmus, Roloff-Handschin, Tim-Christoph, Hansen, Daniel Hvidberg, Groenen, Peter M A

Volltext

Traditional and Digital Biomarkers: Two Worlds Apart? von Babrak, Lmar M., Menetski, Joseph, Rebhan, Michael, Nisato, Giovanni, Zinggeler, Marc, Brasier, Noé, Baerenfaller, Katja, Brenzikofer, Thomas, Baltzer, Laurenz, Vogler, Christian, Gschwind, Leo, Schneider, Cornelia, Streiff, Fabian, Groenen, Peter M.A., Miho, Enkelejda

Volltext

A fully automated image analysis method to quantify lung fibrosis in the bleomycin-induced rat model von Seger, Shanon, Stritt, Manuel, Vezzali, Enrico, Nayler, Oliver, Hess, Patrick, Groenen, Peter M A, Stalder, Anna K

Volltext

Recommendations for robust and reproducible preclinical research in personalised medicine von Fosse, Vibeke, Oldoni, Emanuela, Bietrix, Florence, Budillon, Alfredo, Daskalopoulos, Evangelos P, Fratelli, Maddalena, Gerlach, Björn, Groenen, Peter M A, Hölter, Sabine M, Menon, Julia M L, Mobasheri, Ali, Osborne, Nikki, Ritskes-Hoitinga, Merel, Ryll, Bettina, Schmitt, Elmar, Ussi, Anton, Andreu, Antonio L, McCormack, Emmet

Volltext

Biomarker‐guided clinical development of the first‐in‐class anti‐inflammatory FPR2/ALX agonist ACT‐389949 von Stalder, Anna K., Lott, Dominik, Strasser, Daniel S., Cruz, Hans G., Krause, Andreas, Groenen, Peter M.A., Dingemanse, Jasper

Volltext

Eosinophilic oesophagitis: relevance of mast cell infiltration von Strasser, Daniel S, Seger, Shanon, Bussmann, Christian, Pierlot, Gabin M, Groenen, Peter M A, Stalder, Anna K, Straumann, Alex

Volltext

Impact of high‐altitude therapy on type‐2 immune responses in asthma patients von Boonpiyathad, Tadech, Capova, Gertruda, Duchna, Hans‐Werner, Croxford, Andrew L., Farine, Herve, Dreher, Anita, Clozel, Martine, Schreiber, Juliane, Kubena, Petr, Lunjani, Nonhlanhla, Mirer, David, Rückert, Beate, Satitsuksanoa, Pattraporn, Tan, Ge, Groenen, Peter M. A., Bersuch, Eugen, Akdis, Mübeccel, Strasser, Daniel S., Renner, Ellen D., Akdis, Cezmi A.

Volltext

Serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation von Welford, Richard W. D., Vercauteren, Magali, Trébaul, Annette, Cattaneo, Christophe, Eckert, Doriane, Garzotti, Marco, Sieber, Patrick, Segrestaa, Jérôme, Studer, Rolf, Groenen, Peter M. A., Nayler, Oliver

Volltext

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects von Géhin, Martine, Strasser, Daniel S., Zisowsky, Jochen, Farine, Hervé, Groenen, Peter M.A., Dingemanse, Jasper, Sidharta, Patricia N.

Volltext

Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data von Schäfer, Alexander, Gjerga, Enio, Welford, Richard WD, Renz, Imke, Lehembre, Francois, Groenen, Peter MA, Saez‐Rodriguez, Julio, Aebersold, Ruedi, Gstaiger, Matthias

Volltext

Assessment of Peripheral Serotonin Synthesis Using Stable Isotope‐Labeled Tryptophan von Gehin, Martine, Welford, Richard W.D., Garzotti, Marco, Vercauteren, Magali, Groenen, Peter M.A., Nayler, Oliver, Sidharta, Patricia N., Dingemanse, Jasper

Volltext

Plasma neurofilament light, glial fibrillary acidic protein and lysosphingolipid biomarkers for pharmacodynamics and disease monitoring of GM2 and GM1 gangliosidoses patients von Welford, Richard W.D., Farine, Herve, Steiner, Michel, Garzotti, Marco, Dobrenis, Kostantin, Sievers, Claudia, Strasser, Daniel S., Amraoui, Yasmina, Groenen, Peter M.A., Giugliani, Roberto, Mengel, Eugen

Volltext

Plasma lysosphingomyelin demonstrates great potential as a diagnostic biomarker for Niemann-Pick disease type C in a retrospective study von Welford, Richard W D, Garzotti, Marco, Marques Lourenço, Charles, Mengel, Eugen, Marquardt, Thorsten, Reunert, Janine, Amraoui, Yasmina, Kolb, Stefan A, Morand, Olivier, Groenen, Peter

Volltext

An end-user's perspective on activity-based office concepts von Appel-Meulenbroek, Rianne, Groenen, Peter, Janssen, Ingrid

Volltext

Pharmacokinetic/Pharmacodynamic Modelling of Receptor Internalization with CRTH2 Antagonists to Optimize Dose Selection von Krause, Andreas, Zisowsky, Jochen, Strasser, Daniel S., Gehin, Martine, Sidharta, Patricia N., Groenen, Peter M. A., Dingemanse, Jasper

Volltext

Reverse Engineering of Digital Measures: Inviting Patients to the Conversation von Clay, Ieuan, Peerenboom, Nele, Connors, Dana E, Bourke, Steven, Keogh, Alison, Wac, Katarzyna, Gur-Arie, Tova, Baker, Justin, Bull, Christopher, Cereatti, Andrea, Cormack, Francesca, Eggenspieler, Damien, Foschini, Luca, Ganea, Raluca, Groenen, Peter MA, Gusset, Nicole, Izmailova, Elena, Kanzler, Christoph M, Leyens, Lada, Lyden, Kate, Mueller, Arne, Nam, Julian, Ng, Wan-Fai, Nobbs, David, Orfaniotou, Foteini, Perumal, Thanneer Malai, Piwko, Wojciech, Ries, Anja, Scotland, Alf, Taptiklis, Nick, Torous, John, Vereijken, Beatrix, Xu, Shuai, Baltzer, Laurenz, Vetter, Thorsten, Goldhahn, Jörg, Hoffmann, Steven C

Volltext

PhyloPat: an updated version of the phylogenetic pattern database contains gene neighborhood von Hulsen, Tim, Groenen, Peter M.A, de Vlieg, Jacob, Alkema, Wynand

Volltext

The role of ADME pharmacogenomics in early clinical trials: perspective of the Industry Pharmacogenomics Working Group (I-PWG) von Tremaine, Larry, Brian, William, DelMonte, Terrye, Francke, Stephan, Groenen, Peter, Johnson, Keith, Li, Lei, Pearson, Kimberly, Marshall, Jean-Claude

Volltext

PhyloPat: phylogenetic pattern analysis of eukaryotic genes von Hulsen, Tim, de Vlieg, Jacob, Groenen, Peter M A

Volltext