Kinase Domain Mutants of Bcr-Abl Exhibit Altered Transformation Potency, Kinase Activity, and Substrate Utilization, Irrespective of Sensitivity to Imatinib von Griswold, Ian J., MacPartlin, Mary, Bumm, Thomas, Goss, Valerie L., O'Hare, Thomas, Lee, Kimberly A., Corbin, Amie S., Stoffregen, Eric P., Smith, Caitlyn, Johnson, Kara, Moseson, Erika M., Wood, Lisa J., Polakiewicz, Roberto D., Druker, Brian J., Deininger, Michael W.

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A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice von Johnson, Kara J, Griswold, Ian J, O'Hare, Thomas, Corbin, Amie S, Loriaux, Marc, Deininger, Michael W, Druker, Brian J

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A Specific Need for CRKL in p210BCR-ABL―Induced Transformation of Mouse Hematopoietic Progenitors von SEO, Ji-Heui, WOOD, Lisa J, AGARWAL, Anupriya, O'HARE, Thomas, ELSEA, Collin R, GRISWOLD, Lan J, DEININGER, Michael W. N, IMAMOTO, Akira, DRUKER, Brian J

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Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis von Griswold, Ian J., Shen, Lei J., La Rosée, Paul, Demehri, Shadmehr, Heinrich, Michael C., Braziel, Rita M., McGreevey, Laura, Haley, Andrea D., Giese, Neill, Druker, Brian J., Deininger, Michael W.N.

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Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970 von Corbin, Amie S., Griswold, Ian J., La Rosée, Paul, Yee, Kevin W.H., Heinrich, Michael C., Reimer, Corinne L., Druker, Brian J., Deininger, Michael W.N.

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Size versus polarizability in protein-ligand interactions: binding of noble gases within engineered cavities in phage T4 lysozyme von Quillin, Michael L, Breyer, Wendy A, Griswold, Ian J, Matthews, Brian W

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In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit von Corbin, Amie S., Demehri, Shadmehr, Griswold, Ian J., Wang, Yihan, Metcalf, Chester A., Sundaramoorthi, Raji, Shakespeare, William C., Snodgrass, Joseph, Wardwell, Scott, Dalgarno, David, Iuliucci, John, Sawyer, Tomi K., Heinrich, Michael C., Druker, Brian J., Deininger, Michael W.N.

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The solution structure and interactions of CheW from Thermotoga maritima von Dahlquist, Frederick W, Griswold, Ian J, Zhou, Hongjun, Matison, Mikenzie, Swanson, Ronald V, McIntosh, Lawrence P, Simon, Melvin I

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The dynamic behavior of CheW from Thermotoga maritima in solution, as determined by nuclear magnetic resonance: implications for potential protein–protein interaction sites von Griswold, Ian J, Dahlquist, Frederick W

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Bigger is better: megadalton protein NMR in solution von Griswold, Ian J, Dahlquist, Frederick W

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A Bcr-Abl Mutant Lacking Direct Binding Sites for the Grb2, Cbl and CrkL Adapter Proteins Fails to Induce Leukemia in Mice von Johnson, Kara J., Griswold, Ian J., Corbin, Amie, Deininger, Michael W.N., Druker, Brian J.

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JAK2 V617F Mutation Induces a Myeloproliferative Disorder in Mice von Bumm, Thomas G.P., Elsea, Collin, Wood, Lisa G., Sherbenou, Daniel W., Griswold, Ian J., Loriaux, Marc, Druker, Brian J., Deininger, Michael W.

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Investigation of the Biological Differences between Bcr-Abl Kinase Mutations Resistant to Imatinib von Griswold, Ian J., Bumm, Thomas, O'Hare, Thomas, Moseson, Erika M., Druker, Brian J., Deininger, Michael W.

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In Vitro and In Vivo Activity of the Src/Abl Kinase Inhibitor AP23464 and Analogs Against Activation Loop Mutants of KIT von Corbin, Amie S., Demehri, Shadmehr, Griswold, Ian J., Metcalf, Chester A., Shakespeare, William C., Snodgrass, Joseph, Wardwell, Scott, Dalgarno, David C., Iuliucci, John, Sawyer, Tomi K., Druker, Brian J., Deininger, Michael W.

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Magnetic-Nanoparticle-Based Immunoassays-on-Chip: Materials Synthesis, Surface Functionalization, and Cancer Cell Screening von Zhu, Ying, Kekalo, Katsiaryna, NDong, Christian, Huang, Yu-Yen, Shubitidze, Fridon, Griswold, Karl E., Baker, Ian, Zhang, John X. J.

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An overview of the ORACLES (ObseRvations of Aerosols above CLouds and their intEractionS) project: aerosol–cloud–radiation interactions in the southeast Atlantic basin von Redemann, Jens, Wood, Robert, Zuidema, Paquita, Doherty, Sarah J, Luna, Bernadette, LeBlanc, Samuel E., Diamond, Michael S, Shinozuka, Yohei, Chang, Ian Y, Ueyama, Rei, Pfister, Leonhard, Ryoo, Ju-mee, Dobracki, Amie N., Silva, Arlindo M. da, Longo, Karla M., Kacenelenbogen, Meloë S., Flynn, Connor J., Pistone, Kristina, Knox, Nichola M., Piketh, Stuart J., Haywood, James M., Formenti, Paola, Mallet, Marc, Stier, Philip, Ackerman, Andrew S., Bauer, Susanne E., Fridlind, Ann M., Carmichael, Gregory R., Saide, Pablo E., Ferrada, Gonzalo A., Howell, Steven G., Freitag, Steffen, Cairns, Brian, Holben, Brent N., Knobelspiesse, Kirk D., Tanelli, Simone, L'Ecuyer, Tristan S., Dzambo, Andrew M., Sy, Ousmane O., McFarquhar, Greg M., Poellot, Michael R., Gupta, Siddhant, O'Brien, Joseph R., Nenes, Athanasios, Kacarab, Mary, Wong, Jenny P. S., Small-Griswold, Jennifer D, Thornhill, Kenneth L, Noone, David, Podolske, James R, Schmidt, K. Sebastian, Pilewskie, Peter, Chen, Hong, Cochrane, Sabrina P., Sedlacek, Arthur J., Lang, Timothy J., Stith, Eric, Segal-Rozenhaimer, Michal, Ferrare, Richard A., Burton, Sharon P., Hostetler, Chris A., Diner, David J., Seidel, Felix C., Platnick, Steven E., Myers, Jeffrey S., Meyer, Kerry G., Spangenberg, Douglas A., Maring, Hal, Gao, Lan

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Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks von Peloso, Gina M., Auer, Paul L., Bis, Joshua C., Voorman, Arend, Morrison, Alanna C., Stitziel, Nathan O., Brody, Jennifer A., Khetarpal, Sumeet A., Crosby, Jacy R., Fornage, Myriam, Isaacs, Aaron, Jakobsdottir, Johanna, Feitosa, Mary F., Davies, Gail, Huffman, Jennifer E., Manichaikul, Ani, Davis, Brian, Lohman, Kurt, Joon, Aron Y., Smith, Albert V., Grove, Megan L., Zanoni, Paolo, Redon, Valeska, Demissie, Serkalem, Lawson, Kim, Peters, Ulrike, Carlson, Christopher, Jackson, Rebecca D., Ryckman, Kelli K., Mackey, Rachel H., Robinson, Jennifer G., Siscovick, David S., Schreiner, Pamela J., Mychaleckyj, Josyf C., Pankow, James S., Hofman, Albert, Uitterlinden, Andre G., Harris, Tamara B., Taylor, Kent D., Stafford, Jeanette M., Reynolds, Lindsay M., Marioni, Riccardo E., Dehghan, Abbas, Franco, Oscar H., Patel, Aniruddh P., Lu, Yingchang, Hindy, George, Gottesman, Omri, Bottinger, Erwin P., Melander, Olle, Orho-Melander, Marju, Loos, Ruth J.F., Duga, Stefano, Merlini, Piera Angelica, Farrall, Martin, Goel, Anuj, Asselta, Rosanna, Girelli, Domenico, Martinelli, Nicola, Shah, Svati H., Kraus, William E., Li, Mingyao, Rader, Daniel J., Reilly, Muredach P., McPherson, Ruth, Watkins, Hugh, Ardissino, Diego, Zhang, Qunyuan, Wang, Judy, Tsai, Michael Y., Taylor, Herman A., Correa, Adolfo, Griswold, Michael E., Lange, Leslie A., Starr, John M., Rudan, Igor, Eiriksdottir, Gudny, Launer, Lenore J., Ordovas, Jose M., Levy, Daniel, Chen, Y.-D. Ida, Reiner, Alexander P., Hayward, Caroline, Polasek, Ozren, Deary, Ian J., Borecki, Ingrid B., Liu, Yongmei, Gudnason, Vilmundur, Wilson, James G., van Duijn, Cornelia M., Kooperberg, Charles, Rich, Stephen S., Psaty, Bruce M., Rotter, Jerome I., O’Donnell, Christopher J., Rice, Kenneth, Boerwinkle, Eric, Kathiresan, Sekar, Cupples, L. Adrienne

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Novel genetic loci underlying human intracranial volume identified through genome-wide association von Chouraki, Vincent, Trompet, Stella, Arias-Vasquez, Alejandro, Seshadri, Sudha, Desrivières, Sylvane, Abramovic, Lucija, Aribisala, Benjamin S, Beiser, Alexa, Bernard, Manon, Blanton, Susan H, Bohlken, Marc M, Bralten, Janita, Cuellar-Partida, Gabriel, Ehrlich, Stefan, Goldman, Aaron L, Greven, Corina U, Grimm, Oliver, Guadalupe, Tulio, Haukvik, Unn K, Hilal, Saima, Hofer, Edith, Holmes, Avram J, Jia, Tianye, Klein, Marieke, Lee, Phil H, Lopez, Lorna M, Muetzel, Ryan L, Oosterlaan, Jaap, Pudas, Sara, Pütz, Benno, Rommelse, Nanda, Royle, Natalie A, Sämann, Philipp G, Thomson, Russell, Toro, Roberto, Trabzuni, Daniah, Wolf, Christiane, Zijdenbos, Alex, Zwiers, Marcel P, Aggarwal, Neelum T, Andreassen, Ole A, Barral, Sandra, Becker, James T, van Bokhoven, Hans, Brouwer, Rachel M, Brunner, Han G, Buitelaar, Jan K, Dale, Anders M, Davies, Gareth E, De Geus, Eco J C, de Zubicaray, Greig I, DeStefano, Anita L, Duggirala, Ravi, Evans, Denis A, Fedko, Iryna O, Fernández, Guillén, Fisher, Simon E, Ford, Ian, Francks, Clyde, Fukunaga, Masaki, Glahn, David C, Gruber, Oliver, Guelfi, Sebastian, Hansell, Narelle K, Hegenscheid, Katrin, Heslenfeld, Dirk J, Hottenga, Jouke-Jan, Johnson, Robert, Jönsson, Erik G, Kloszewska, Iwona, Kochunov, Peter, Kwok, John B, Lawrie, Stephen M, Lemaître, Hervé, Liu, Xinmin, Longo, Dan L, Melle, Ingrid, Morris, Derek W, Mühleisen, Thomas W, Nichols, Thomas E, Pausova, Zdenka, Pike, G Bruce, Psaty, Bruce M, Rietschel, Marcella, Ryten, Mina, Saykin, Andrew J, Simmons, Andy, Steen, Vidar M, Stott, David J, Sussmann, Jessika E, Tiemeier, Henning, Uitterlinden, Andre G, Wassink, Thomas H, Weale, Michael E, Weiner, Michael W, Westman, Eric, White, Tonya, Wright, Margaret J, Franke, Barbara, Debette, Stéphanie

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Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes von Feliciano, Pamela, Zhou, Xueya, Astrovskaya, Irina, Turner, Tychele N., Wang, Tianyun, Brueggeman, Leo, Barnard, Rebecca, Hsieh, Alexander, Snyder, LeeAnne Green, Muzny, Donna M., Sabo, Aniko, Gibbs, Richard A., Eichler, Evan E., O’Roak, Brian J., Michaelson, Jacob J., Volfovsky, Natalia, Shen, Yufeng, Chung, Wendy K.

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Place-Its: a study of location-based reminders on mobile phones von Sohn, Timothy, Li, Kevin A., Lee, Gunny, Smith, Ian, Scott, James, Griswold, William G.

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