A dideazatetrahydrofolate analog lacking a chiral center at C-6: N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5yl)ethyl[benzoyl]-L-glutamic acid is an inhibitor of... von Taylor, Edward C, Kuhnt, Dietmar, Shih, Chuan, Rinzel, Sharon M, Grindey, Gerald B, Barredo, Julio, Jannatipour, Mehrdad, Moran, Richard G

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Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine) von HERTEL, L. W, BODER, G. B, KROIN, J. S, RINZEL, S. M, POORE, G. A, TODD, G. C, GRINDEY, G. B

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Sulfonylureas: a new class of cancer chemotherapeutic agents von Mohamadi, Fariborz, Spees, Michael M, Grindey, Gerald B

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CELLULAR ELIMINATION OF 2',2'-DIFLUORODEOXYCYTIDINE 5'-TRIPHOSPHATE - A MECHANISM OF SELF-POTENTIATION von HEINEMANN, XU, YZ, CHUBB, S, SEN, A, HERTEL, LW, GRINDEY, GB, PLUNKETT, W

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Synthesis and biological activity of acyclic analogs of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid von Shih, Chuan, Gossett, Lynn S, Worzalla, John F, Rinzel, Sharon M, Grindey, Gerald B, Harrington, Philip M, Taylor, Edward C

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Augmentation of the therapeutic activity of lometrexol [(6-R)5,10-dideazatetrahydrofolate] by oral folic acid von ALATI, T, WORZALLA, J. F, SHIH, C, BEWLEY, J. R, LEWIS, S, MORAN, R. G, GRINDEY, G. B

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A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors von Habeck, L L, Leitner, T A, Shackelford, K A, Gossett, L S, Schultz, R M, Andis, S L, Shih, C, Grindey, G B, Mendelsohn, L G

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Action of 2',2'-difluorodeoxycytidine on DNA synthesis von PENG HUANG, CHUBB, S, HERTEL, L. W, GRINDEY, G. B, PLUNKETT, W

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Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine von Heinemann, V, Xu, Y Z, Chubb, S, Sen, A, Hertel, L W, Grindey, G B, Plunkett, W

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N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)urea, a novel agent equally cytotoxic to nonproliferating human colon adenocarcinoma cells von HOUGHTON, P. J, BAILEY, F. C, GERMAIN, G. S, GRINDEY, G. B, WITT, B. C, HOUGHTON, J. A

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Sulfonimidamide analogs of oncolytic sulfonylureas von TOTH, J. E, GRINDEY, G. B, WEIR, L. C, WORZALLA, J. F, EHLHARDT, W. J, RAY, J. E, BODER, G. B, BEWLEY, J. R, KLINGERMAN, K. K, GATES, S. B, RINZEL, S. M, SCHULTZ, R. M

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Sulfonimidamide Analogs of Oncolytic Sulfonylureas † ,1 von Toth, John E, Grindey, Gerald B, Ehlhardt, William J, Ray, James E, Boder, George B, Bewley, Jesse R, Klingerman, Kim K, Gates, Susan B, Rinzel, Sharon M, Schultz, Richard M, Weir, Leonard C, Worzalla, John F

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Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas von Ehlhardt, William J, Woodland, Joseph M, Worzalla, John F, Bewley, Jesse R, Grindey, Gerald B, Todd, Glen C, Toth, John E, Howbert, J. Jeffry

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Automated measurement of transplantable solid tumors using digital electronic calipers interfaced to a microcomputer von WORZALLA, J. F, BEWLEY, J. R, GRINDEY, G. B

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Evaluation of ribonucleoside and deoxyribonucleoside triphosphate pools in cultured leukemia cells during exposure to methotrexate or methotrexate plus thymidine von Kinahan, J J, Otten, M, Grindey, G B

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Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-BIS(2-chloroethyl)-1-nitrosourea(BCNU) von Dolan, M.Eileen, Pegg, Anthony E., Moschel, Robert C., Grindey, Gerald B.

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Characterization of folate receptor from normal and neoplastic murine tissue: influence of dietary folate on folate receptor expression von GATES, S. B, MENDELSOHN, L. G, SHACKELFORD, K. A, HABECK, L. L, KURSAR, J. D, GOSSETT, L. S, WORZALLA, J. F, SHIH, C, GRINDEY, G. B

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Synthesis and antitumor activity of 5-deaza-5,6,7,8-tetrahydrofolic acid and its N10-substituted analogs von Taylor, Edward C, Hamby, James M, Shih, Chuan, Grindey, Gerald B, Rinzel, Sharon M, Beardsley, G. Peter, Moran, Richard G

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Adriamycin and daunorubicin: a comparison of antitumor activities and tissue uptake in mice following immunosuppression von Schwartz, H S, Grindey, G B

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Effects of allopurinol on the therapeutic efficacy of methotrexate von Grindey, G B, Moran, R G

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