Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation von Benabdallah, Nezha S., Williamson, Iain, Illingworth, Robert S., Kane, Lauren, Boyle, Shelagh, Sengupta, Dipta, Grimes, Graeme R., Therizols, Pierre, Bickmore, Wendy A.

Volltext

Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing von Pradeepa, Madapura M, Sutherland, Heidi G, Ule, Jernej, Grimes, Graeme R, Bickmore, Wendy A

Volltext

Histone H3 globular domain acetylation identifies a new class of enhancers von Pradeepa, Madapura M, Grimes, Graeme R, Kumar, Yatendra, Olley, Gabrielle, Taylor, Gillian C A, Schneider, Robert, Bickmore, Wendy A

Volltext

Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination von Eskeland, Ragnhild, Leeb, Martin, Grimes, Graeme R., Kress, Clémence, Boyle, Shelagh, Sproul, Duncan, Gilbert, Nick, Fan, Yuhong, Skoultchi, Arthur I., Wutz, Anton, Bickmore, Wendy A.

Volltext

Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect von Olley, Gabrielle, Pradeepa, Madapura M., Grimes, Graeme R., Piquet, Sandra, Polo, Sophie E., FitzPatrick, David R., Bickmore, Wendy A., Boumendil, Charlene

Volltext

Human centromere repositioning activates transcription and opens chromatin fibre structure von Naughton, Catherine, Huidobro, Covadonga, Catacchio, Claudia R., Buckle, Adam, Grimes, Graeme R., Nozawa, Ryu-Suke, Purgato, Stefania, Rocchi, Mariano, Gilbert, Nick

Volltext

DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency von McLaughlin, Katy, Flyamer, Ilya M., Thomson, John P., Mjoseng, Heidi K., Shukla, Ruchi, Williamson, Iain, Grimes, Graeme R., Illingworth, Robert S., Adams, Ian R., Pennings, Sari, Meehan, Richard R., Bickmore, Wendy A.

Volltext

Characterisation of a nucleo-adhesome von Byron, Adam, Griffith, Billie G. C., Herrero, Ana, Loftus, Alexander E. P., Koeleman, Emma S., Kogerman, Linda, Dawson, John C., McGivern, Niamh, Culley, Jayne, Grimes, Graeme R., Serrels, Bryan, von Kriegsheim, Alex, Brunton, Valerie G., Frame, Margaret C.

Volltext

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs von Griffith, Billie G. C., Upstill-Goddard, Rosanna, Brunton, Holly, Grimes, Graeme R., Biankin, Andrew V., Serrels, Bryan, Byron, Adam, Frame, Margaret C.

Volltext

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma von Younger, Nicholas T, Wilson, Mollie L, Martinez Lyons, Anabel, Jarman, Edward J, Meynert, Alison M, Grimes, Graeme R, Gournopanos, Konstantinos, Waddell, Scott H, Tennant, Peter A, Wilson, David H, Guest, Rachel V, Wigmore, Stephen J, Acosta, Juan Carlos, Kendall, Timothy J, Taylor, Martin S, Sproul, Duncan, Mill, Pleasantine, Boulter, Luke

Volltext

Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia von Hall, Hildegard Nikki, Bengani, Hemant, Hufnagel, Robert B, Damante, Giuseppe, Ansari, Morad, Marsh, Joseph A, Grimes, Graeme R, Kriegsheim, Alex von, Moore, David, McKie, Lisa, Rahmat, Jamalia, Mio, Catia, Blyth, Moira, Keng, Wee Teik, Islam, Lily, McEntargart, Meriel, Mannens, Marcel M, Heyningen, Veronica Van, Rainger, Joe, Brooks, Brian P, FitzPatrick, David R

Volltext

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip von Pradeepa, Madapura M, McKenna, Fionnuala, Taylor, Gillian C A, Bengani, Hemant, Grimes, Graeme R, Wood, Andrew J, Bhatia, Shipra, Bickmore, Wendy A

Volltext

Anterior-posterior differences in HoxD chromatin topology in limb development von Williamson, Iain, Eskeland, Ragnhild, Lettice, Laura A, Hill, Alison E, Boyle, Shelagh, Grimes, Graeme R, Hill, Robert E, Bickmore, Wendy A

Volltext

PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells von Illingworth, Robert S, Botting, Catherine H, Grimes, Graeme R, Bickmore, Wendy A, Eskeland, Ragnhild

Volltext

BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome von Olley, Gabrielle, Ansari, Morad, Bengani, Hemant, Grimes, Graeme R., Rhodes, James, von Kriegsheim, Alex, Blatnik, Ana, Stewart, Fiona J., Wakeling, Emma, Carroll, Nicola, Ross, Alison, Park, Soo-Mi, Bickmore, Wendy A., Pradeepa, Madapura M., FitzPatrick, David R.

Volltext

Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma von Ewing, Ailith, Meynert, Alison, Churchman, Michael, Grimes, Graeme R., Hollis, Robert L., Herrington, C. Simon, Rye, Tzyvia, Bartos, Clare, Croy, Ian, Ferguson, Michelle, Lennie, Mairi, McGoldrick, Trevor, McPhail, Neil, Siddiqui, Nadeem, Dowson, Suzanne, Glasspool, Rosalind, Mackean, Melanie, Nussey, Fiona, McDade, Brian, Ennis, Darren, McMahon, Lynn, Matakidou, Athena, Dougherty, Brian, March, Ruth, Barrett, J. Carl, McNeish, Iain A., Biankin, Andrew, Roxburgh, Patricia, Gourley, Charlie, Semple, Colin A.

Volltext

Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF von Semple, Fiona, MacPherson, Heather, Webb, Sheila, Cox, Sarah L., Mallin, Lucy J., Tyrrell, Christine, Grimes, Graeme R., Semple, Colin A., Nix, Matthew A., Millhauser, Glenn L., Dorin, Julia R.

Volltext

Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops von Williamson, Iain, Boyle, Shelagh, Grimes, Graeme R, Friman, Elias T, Bickmore, Wendy A

Volltext

Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome von Olley, Gabrielle, Ansari, Morad, Bengani, Hemant, Grimes, Graeme R., Rhodes, James, von Kriegsheim, Alex, Blatnik, Ana, Stewart, Fiona J., Wakeling, Emma, Carroll, Nicola, Ross, Alison, Park, Soo-Mi, Bickmore, Wendy A., Pradeepa, Madapura M., FitzPatrick, David R.

Volltext

Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins von Pradeepa, Madapura M, Grimes, Graeme R, Taylor, Gillian C A, Sutherland, Heidi G, Bickmore, Wendy A

Volltext