Inhibition of P‐glycoprotein enhances transport of imipramine across the blood–brain barrier: microdialysis studies in conscious freely moving rats von O'Brien, FE, Clarke, G, Fitzgerald, P, Dinan, TG, Griffin, BT, Cryan, JF

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Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives von Donovan, Maria D., Griffin, Brendan T., Kharoshankaya, Liudmila, Cryan, John F., Boylan, Geraldine B.

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Knowledge of Adverse Drug Reaction Reporting and the Pharmacovigilance of Biological Medicines: A Survey of Healthcare Professionals in Ireland von O’Callaghan, J., Griffin, B. T., Morris, J. M., Bermingham, Margaret

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PCV37 USE OF TIME-STAMPED HOSPITAL DATA TO EXAMINE CARE PATTERNS OF ACUTE CORONARY SYNDROME PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION von Wang, C, He, J, McCollam, PL, Bae, JP, Griffin, BT

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PCV30 CLOPIDOGREL LOADING DOSE AND CARDIOVASCULAR OUTCOMES IN ACUTE CORONARY SYNDROME PATIENTS WHO UNDERGO PERCUTANEOUS CORONARY INTERVENTION von Wang, C, He, J, Bae, JP, McCollam, PL, Griffin, BT

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Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network von Vinarov, Z, Abrahamsson, B, Artursson, P, Batchelor, H, Berben, P, Bernkop-Schnürch, A, Butler, J, Ceulemans, J, Davies, N, Dupont, D, Flaten, GE, Fotaki, N, Griffin, BT, Jannin, V, Keemink, J, Kesisoglou, F, Koziolek, M, Kuentz, M, Mackie, A, Meléndez-Martínez, AJ, McAllister, M, Müllertz, A, O'Driscoll, CM, Parrott, N, Paszkowska, J, Pavek, P, Porter, CJH, Reppas, C, Stillhart, C, Sugano, K, Toader, E, Valentová, K, Vertzoni, M, De Wildt, SN, Wilson, CG, Augustijns, P

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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries von Leahy, Justin J.J., Golding, Bernard T., Griffin, Roger J., Hardcastle, Ian R., Richardson, Caroline, Rigoreau, Laurent, Smith, Graeme C.M.

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Discovery of Potent Chromen-4-one Inhibitors of the DNA-Dependent Protein Kinase (DNA-PK) Using a Small-Molecule Library Approach von Hardcastle, Ian R, Cockcroft, Xiaoling, Curtin, Nicola J, El-Murr, Marine Desage, Leahy, Justin J. J, Stockley, Martin, Golding, Bernard T, Rigoreau, Laurent, Richardson, Caroline, Smith, Graeme C. M, Griffin, Roger J

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Selective Benzopyranone and Pyrimido[2,1-a]isoquinolin-4-one Inhibitors of DNA-Dependent Protein Kinase:  Synthesis, Structure−Activity Studies, and Radiosensitization of a Human T... von Griffin, Roger J, Fontana, Gabriele, Golding, Bernard T, Guiard, Sophie, Hardcastle, Ian R, Leahy, Justin J. J, Martin, Niall, Richardson, Caroline, Rigoreau, Laurent, Stockley, Martin, Smith, Graeme C. M

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Resistance-Modifying Agents. 9. Synthesis and Biological Properties of Benzimidazole Inhibitors of the DNA Repair Enzyme Poly(ADP-ribose) Polymerase von White, Alex W, Almassy, Robert, Calvert, A. Hilary, Curtin, Nicola J, Griffin, Roger J, Hostomsky, Zdenek, Maegley, Karen, Newell, David R, Srinivasan, Sheila, Golding, Bernard T

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Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 Inhibitors von Skalitzky, Donald J, Marakovits, Joseph T, Maegley, Karen A, Ekker, Anne, Yu, Xiao-Hong, Hostomsky, Zdenek, Webber, Stephen E, Eastman, Brian W, Almassy, Robert, Li, Jianke, Curtin, Nicola J, Newell, David R, Calvert, A. Hilary, Griffin, Roger J, Golding, Bernard T

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Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles von Arris, Christine E, Boyle, F. Thomas, Calvert, A. Hilary, Curtin, Nicola J, Endicott, Jane A, Garman, Elspeth F, Gibson, Ashleigh E, Golding, Bernard T, Grant, Sharon, Griffin, Roger J, Jewsbury, Philip, Johnson, Louise N, Lawrie, Alison M, Newell, David R, Noble, Martin E. M, Sausville, Edward A, Schultz, Robert, Yu, Wyatt

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Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor von Newell, David R, Davies, Thomas G, Bentley, Johanne, Arris, Christine E, Boyle, F. Thomas, Curtin, Nicola J, Endicott, Jane A, Gibson, Ashleigh E, Golding, Bernard T, Griffin, Roger J, Hardcastle, Ian R, Jewsbury, Philip, Johnson, Louise N, Mesguiche, Veronique, Noble, Martin E.M, Tucker, Julie A, Wang, Lan, Whitfield, Hayley J

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Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction von Hardcastle, Ian R., Ahmed, Shafiq U., Atkins, Helen, Calvert, A. Hilary, Curtin, Nicola J., Farnie, Gillian, Golding, Bernard T., Griffin, Roger J., Guyenne, Sabrina, Hutton, Claire, Källblad, Per, Kemp, Stuart J., Kitching, Martin S., Newell, David R., Norbedo, Stefano, Northen, Julian S., Reid, Rebecca J., Saravanan, K., Willems, Henriëtte M.G., Lunec, John

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2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK) von Hollick, Jonathan J., Golding, Bernard T., Hardcastle, Ian R., Martin, Niall, Richardson, Caroline, Rigoreau, Laurent J.M., Smith, Graeme C.M., Griffin, Roger J.

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Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation von Pennati, Marzia, Campbell, Allyson J, Curto, Maria, Binda, Mara, Cheng, Yuzhu, Wang, Lan-Zeng, Curtin, Nicola, Golding, Bernard T, Griffin, Roger J, Hardcastle, Ian R, Henderson, Andrew, Zaffaroni, Nadia, Newell, David R

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N 2 -Substituted O 6 -Cyclohexylmethylguanine Derivatives:  Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 von Hardcastle, Ian R., Arris, Christine E., Bentley, Johanne, Boyle, F. Thomas, Chen, Yuzhu, Curtin, Nicola J., Endicott, Jane A., Gibson, Ashleigh E., Golding, Bernard T., Griffin, Roger J., Jewsbury, Philip, Menyerol, Jerome, Mesguiche, Veronique, Newell, David R., Noble, Martin E. M., Pratt, David J., Wang, Lan-Zhen, Whitfield, Hayley J.

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Designing inhibitors of cyclin-dependent kinases von Hardcastle, Ian R, Golding, Bernard T, Griffin, Roger J

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Resistance-Modifying Agents. 5. Synthesis and Biological Properties of Quinazolinone Inhibitors of the DNA Repair Enzyme Poly(ADP-ribose) Polymerase (PARP) von Griffin, Roger J, Srinivasan, Sheila, Bowman, Karen, Calvert, A. Hilary, Curtin, Nicola J, Newell, David R, Pemberton, Louise C, Golding, Bernard T

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Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064 von Bowman, KJ, White, A, Golding, BT, Griffin, RJ, Curtin, NJ

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