High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples von Payton, Jacqueline E, Grieselhuber, Nicole R, Chang, Li-Wei, Murakami, Mark, Geiss, Gary K, Link, Daniel C, Nagarajan, Rakesh, Watson, Mark A, Ley, Timothy J

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Confronting the therapeutic misconception von Grieselhuber, Nicole R., MD, PhD, Kodner, Ira J., MD, FACS, Brown, Douglas, PhD, Yu, Jennifer, MD

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The multi-CDK inhibitor dinaciclib reverses bromo- and extra-terminal domain (BET) inhibitor resistance in acute myeloid leukemia via inhibition of Wnt/β-catenin signaling von Marr, Alexander R, Halpin, Madeline, Corbin, Dominique L, Asemelash, Yerdanos, Sher, Steven, Gordon, Britten K, Whipp, Ethan C, Mitchell, Shaneice, Harrington, Bonnie K, Orwick, Shelley, Benrashid, Samon, Goettl, Virginia M, Yildiz, Vedat, Mitchell, Andrew D, Cahn, Olivia, Mims, Alice S, Larkin, Karilyn T M, Long, Meixao, Blachly, James, Woyach, Jennifer A, Lapalombella, Rosa, Grieselhuber, Nicole R

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Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition von Zhang, Pu, Brinton, Lindsey T., Williams, Katie, Sher, Steven, Orwick, Shelley, Tzung-Huei, Lai, Mims, Alice S., Coss, Christopher C., Kulp, Samuel K., Youssef, Youssef, Chan, Wing Keung, Mitchell, Shaneice, Mustonen, Allison, Cannon, Matthew, Phillips, Hannah, Lehman, Amy M., Kauffman, Tierney, Beaver, Larry, Canfield, Daniel, Grieselhuber, Nicole R., Alinari, Lapo, Sampath, Deepa, Yan, Pearlly, Byrd, John C., Blachly, James S., Lapalombella, Rosa

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Novel Targeted Therapeutics in Acute Myeloid Leukemia: an Embarrassment of Riches von Grieselhuber, Nicole R., Mims, Alice S.

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Notch signaling in acute promyelocytic leukemia von Grieselhuber, N R, Klco, J M, Verdoni, A M, Lamprecht, T, Sarkaria, S M, Wartman, L D, Ley, T J

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The Incidence of Invasive Fungal Infections in Patients With AML Treated With a Hypomethylating Agent von Ozga, Michael, Huang, Ying, Blachly, James S., Grieselhuber, Nicole R., Wall, Sarah, Larkin, Karilyn, Haque, Tamanna, Walker, Alison R., Bhatnagar, Bhavana, Behbehani, Gregory, Vasu, Sumithira, Maakaron, Joseph E., Lustberg, Mark, Mims, Alice S.

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Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia von Mitchell, Shaneice R., Larkin, Karilyn, Grieselhuber, Nicole R., Lai, Tzung-Huei, Cannon, Matthew, Orwick, Shelley, Sharma, Pratibha, Asemelash, Yerdanose, Zhang, Pu, Goettl, Virginia M., Beaver, Larry, Mims, Alice, Puduvalli, Vinay K., Blachly, James S., Lehman, Amy, Harrington, Bonnie, Henderson, Sally, Breitbach, Justin T., Williams, Katie E., Dong, Shuai, Baloglu, Erkan, Senapedis, William, Kirschner, Karl, Sampath, Deepa, Lapalombella, Rosa, Byrd, John C.

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Diagnostic utility of bronchoscopy in newly diagnosed acute leukemia patients von Koenig, Kristin L., Curley, Thomas P., Mani, Shylaja, Keiter, Ashleigh, Zhao, Qiuhong, Behbehani, Gregory K., Bhatnagar, Bhavana, Blachly, James S., Haque, Tamanna Z., Larkin, Karilyn T. M., Long, Meixiao, Mims, Alice S., Vasu, Sumithira, Wall, Sarah A., Byrd, John C., Lustberg, Mark, Walker, Alison R., Grieselhuber, Nicole R.

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A protease-resistant PML-RARα has increased leukemogenic potential in a murine model of acute promyelocytic leukemia von Uy, Geoffrey L., Lane, Andrew A., Welch, John S., Grieselhuber, Nicole R., Payton, Jacqueline E., Ley, Timothy J.

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Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis von Marr, Alexander, Halpin, Madeline, Corbin, Dominique, Gordon, Britten, Benrashid, Samon, Whipp, Ethan C., Gharghabi, Mehdi, Truxall, Jean, Cahn, Olivia, Koenig, Kristin L, Larkin, Karilyn T., Woyach, Jennifer A., Lapalombella, Rosa, Grieselhuber, Nicole R.

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BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor von Ozer, Hatice Gulcin, El-Gamal, Dalia, Powell, Ben, Hing, Zachary A, Blachly, James S, Harrington, Bonnie, Mitchell, Shaneice, Grieselhuber, Nicole R, Williams, Katie, Lai, Tzung-Huei, Alinari, Lapo, Baiocchi, Robert A, Brinton, Lindsey, Baskin, Elizabeth, Cannon, Matthew, Beaver, Larry, Goettl, Virginia M, Lucas, David M, Woyach, Jennifer A, Sampath, Deepa, Lehman, Amy M, Yu, Lianbo, Zhang, Jiazhong, Ma, Yan, Zhang, Ying, Spevak, Wayne, Shi, Songyuan, Severson, Paul, Shellooe, Rafe, Carias, Heidi, Tsang, Garson, Dong, Ken, Ewing, Todd, Marimuthu, Adhirai, Tantoy, Christina, Walters, Jason, Sanftner, Laura, Rezaei, Hamid, Nespi, Marika, Matusow, Bernice, Habets, Gaston, Ibrahim, Prabha, Zhang, Chao, Mathé, Ewy A, Bollag, Gideon, Byrd, John C, Lapalombella, Rosa

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A Phase 1b/2 Trial of Liposomal Cytarabine and Daunorubicin (CPX-351) in Intermediate to High-Risk Acute Myeloid Leukemia for Patients Who Have Failed an Initial Cycle of Induction... von Pontious, Corbin, Garzon, Ramiro, Blachly, James S., Blaser, Bradley Wayne, Choe, Hannah, Grieselhuber, Nicole R., Long, Meixiao, Vasu, Sumithira, Wall, Sarah A, Larkin, Karilyn T., Eisfeld, Ann-Kathrin, Koenig, Kristin L, Sahasrabudhe, Kieran D, Sanchez-Petitto, Gabriela, Saad, Ayman, Bhatnagar, Bhavana, Lyberger, Justin, Borate, Uma M., Mims, Alice, Jonas, Brian A., Behbehani, Gregory K

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The PKC-β Inhibitor MS-553 Displays Preclinical Efficacy in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia von Gordon, Britten, Muhowski, Elizabeth, Ravikrishnan, Janani, Thangavadivel, Shanmugapriya, Benrashid, Samon, He, Alexander, Misra, Shrilekha, Lai, Tzung-Huei, Marr, Alexander, Yu, Lianbo, Walker, Brandi, Perry, Elizabeth, Grieselhuber, Nicole R., Rogers, Kerry A, Blachly, James S., Kittai, Adam S, Bhat, Seema A, Byrd, John C., Niesman, Michael, Zhang, Kai, Sampath, Deepa, Woyach, Jennifer A.

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Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition von Zhang, Pu, Brinton, Lindsey T., Williams, Katie, Sher, Steven, Orwick, Shelley, Tzung-Huei, Lai, Mims, Alice S., Coss, Christopher C., Kulp, Samuel K., Youssef, Youssef, Chan, Wing Keung, Mitchell, Shaneice, Mustonen, Allison, Cannon, Matthew, Phillips, Hannah, Lehman, Amy M., Kauffman, Tierney, Beaver, Larry, Canfield, Daniel, Grieselhuber, Nicole R., Alinari, Lapo, Sampath, Deepa, Yan, Pearlly, Byrd, John C., Blachly, James S., Lapalombella, Rosa

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Additional file 1 of The multi-CDK inhibitor dinaciclib reverses bromo- and extra-terminal domain (BET) inhibitor resistance in acute myeloid leukemia via inhibition of Wnt/β-caten... von Marr, Alexander R., Halpin, Madeline, Corbin, Dominique L., Asemelash, Yerdanos, Sher, Steven, Gordon, Britten K., Whipp, Ethan C., Mitchell, Shaneice, Harrington, Bonnie K., Orwick, Shelley, Benrashid, Samon, Goettl, Virginia M., Yildiz, Vedat, Mitchell, Andrew D., Cahn, Olivia, Mims, Alice S., Larkin, Karilyn T. M., Long, Meixao, Blachly, James, Woyach, Jennifer A., Lapalombella, Rosa, Grieselhuber, Nicole R.

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The multi-CDK inhibitor dinaciclib reverses bromo- and extra-terminal domain (BET) inhibitor resistance in acute myeloid leukemia via inhibition of Wnt/[beta]-catenin signaling von Marr, Alexander R, Halpin, Madeline, Corbin, Dominique L, Asemelash, Yerdanos, Sher, Steven, Gordon, Britten K, Whipp, Ethan C, Mitchell, Shaneice, Harrington, Bonnie K, Orwick, Shelley, Benrashid, Samon, Goettl, Virginia M, Yildiz, Vedat, Mitchell, Andrew D, Cahn, Olivia, Mims, Alice S, Larkin, Karilyn T. M, Long, Meixao, Blachly, James, Woyach, Jennifer A, Lapalombella, Rosa, Grieselhuber, Nicole R

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Trametinib for the Treatment of IGHV4-34, MAP2K1 Mutant Variant Hairy Cell Leukemia von Andritsos, Leslie A., Anghelina, Mirela, Grieselhuber, Nicole R., Roychowdhury, Sameek, Reeser, Julie, Timmers, Cynthia, Freud, Aharon G., Blachly, James S., Lucas, David M., Lozanski, Gerard, Jones, Jeffrey, Rogers, Kerry A., Zhao, Weiqiang, Grever, Michael R.

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Dealing with complexity: prognostic implications of karyotype and mutations in chronic lymphocytic leukemia von Grieselhuber, Nicole R., Asquith, Justin M., Andritsos, Leslie A.

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The Novel BET Inhibitor PLX51107 Has In Vitro and In Vivo Activity Against Acute Myeloid Leukemia von Grieselhuber, Nicole R., Mitchell, Shaneice R., Orwick, Shelley, Harrington, Bonnie K., Goettl, Virginia M., Walker, Alison R., Bhatnagar, Bhavana, Mims, Alice S., Klisovic, Rebecca B., Vasu, Sumithra, Blum, William, Blachly, James S., Lucas, David M., Garzon, Ramiro, Lapalombella, Rosa, Byrd, John C.

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