The novel cyclin-dependent kinase inhibitor dinaciclib (SCH727965) promotes apoptosis and abrogates microenvironmental cytokine protection in chronic lymphocytic leukemia cells von Johnson, A J, Yeh, Y-Y, Smith, L L, Wagner, A J, Hessler, J, Gupta, S, Flynn, J, Jones, J, Zhang, X, Bannerji, R, Grever, M R, Byrd, J C

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Phase I study of 5-aza-2′-deoxycytidine in combination with valproic acid in non-small-cell lung cancer von Chu, B. F., Karpenko, M. J., Liu, Z., Aimiuwu, J., Villalona-Calero, M. A., Chan, K. K., Grever, M. R., Otterson, G. A.

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Risk factors for tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with the cyclin-dependent kinase inhibitor, flavopiridol von Blum, K A, Ruppert, A S, Woyach, J A, Jones, J A, Andritsos, L, Flynn, J M, Rovin, B, Villalona-Calero, M, Ji, J, Phelps, M, Johnson, A J, Grever, M R, Byrd, J C

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Rituximab Using A Thrice Weekly Dosing Schedule in B-Cell Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Demonstrates Clinical Activity and Acceptable Toxicity von Byrd, J C, Murphy, T, Howard, R S, Lucas, M S, Goodrich, A, Park, K, Pearson, M, Waselenko, J K, Ling, G, Grever, M R, Grillo-Lopez, A J, Rosenberg, J, Kunkel, L, Flinn, I W

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The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells von LUCAS, D. M, DAVIS, M. E, GREVER, M. R, PARTHUN, M. R, MONE, A. P, KITADA, S, CUNNINGHAM, K. D, FLAX, E. L, WICKHAM, J, REED, J. C, BYRD, J. C

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Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic... von KLISOVIC, M. I, MAGHRABY, E. A, RUSH, L. J, PLASS, C, GREVER, M. R, BYRD, J. C, MARCUCCI, G, PARTHUN, M. R, GUIMOND, M, SKLENAR, A. R, WHITMAN, S. P, CHAN, K. K, MURPHY, T, ANON, J, ARCHER, K. J

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Dinaciclib is a novel cyclin-dependent kinase inhibitor with significant clinical activity in relapsed and refractory chronic lymphocytic leukemia von Flynn, J, Jones, J, Johnson, A J, Andritsos, L, Maddocks, K, Jaglowski, S, Hessler, J, Grever, M R, Im, E, Zhou, H, Zhu, Y, Zhang, D, Small, K, Bannerji, R, Byrd, J C

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Frequency and Clinical Significance of the Expression of the Multidrug Resistance Proteins MDR1/P-Glycoprotein, MRP1, and LRP in Acute Myeloid Leukemia. A Southwest Oncology Group... von Leith, Catherine P., Kopecky, Kenneth J., Chen, I-Ming, Eijdems, Lisette, Slovak, Marilyn L., McConnell, Thomas S., Head, David R., Weick, James, Grever, Michael R., Appelbaum, Frederick R., Willman, Cheryl L.

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Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor von ORLOWSKI, R. Z, ESWARA, J. R, LAFOND-WALKER, A, GREVER, M. R, ORLOWSKI, M, DANG, C. V

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Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin von Flinn, Ian W., Kopecky, Kenneth J., Foucar, M. Kathryn, Head, David, Bennett, John M., Hutchison, Robert, Corbett, William, Cassileth, Peter, Habermann, Thomas, Golomb, Harvey, Rai, Kanti, Eisenhauer, Elizabeth, Appelbaum, Frederick, Cheson, Bruce, Grever, Michael R.

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Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53 von BYRD, J. C, SHINN, C, WASELENKO, J. K, FUCHS, E. J, LEHMAN, T. A, NGUYEN, P. L, FLINN, I. W, DIEHL, L. F, SAUSVILLE, E, GREVER, M. R

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Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity von Callahan, K P, Minhajuddin, M, Corbett, C, Lagadinou, E D, Rossi, R M, Grose, V, Balys, M M, Pan, L, Jacob, S, Frontier, A, Grever, M R, Lucas, D M, Kinghorn, A D, Liesveld, J L, Becker, M W, Jordan, C T

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Filgrastim and alemtuzumab (Campath-1H) for refractory chronic lymphocytic leukemia von LIN, T. S, FLINN, I. W, LUCAS, M. S, PORCU, P, SICKLER, J, MORAN, M. E, LUCAS, D. M, HEEREMA, N. A, GREVER, M. R, BYRD, J. C

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Outcome of patients with relapsed or refractory chronic lymphocytic leukemia treated with flavopiridol: impact of genetic features von Woyach, J A, Lozanski, G, Ruppert, A S, Lozanski, A, Blum, K A, Jones, J A, Flynn, J M, Johnson, A J, Grever, M R, Heerema, N A, Byrd, J C

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Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia von Rosenwald, A, Alizadeh, A A, Widhopf, G, Simon, R, Davis, R E, Yu, X, Yang, L, Pickeral, O K, Rassenti, L Z, Powell, J, Botstein, D, Byrd, J C, Grever, M R, Cheson, B D, Chiorazzi, N, Wilson, W H, Kipps, T J, Brown, P O, Staudt, L M

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HLA-DR-, CD33+, CD56+, CD16- myeloid/natural killer cell acute leukemia : a previously unrecognized form of acute leukemia potentially misdiagnosed as french-american-british acute... von SCOTT, A. A, HEAD, D. R, WAXMAN, S, WHALEN, M. M, BANKHURST, A. D, RICHTER, L. C, GROGAN, T. M, WILLMAN, C. L, KOPECKY, K. J, APPELBAUM, F. R, THEIL, K. S, GREVER, M. R, I-MING CHEN, WHITTAKER, M. H, GRIFFITH, B. B, LICHT, J. D

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Impact of targeted therapy on outcome of chronic lymphocytic leukemia patients with relapsed del(17p13.1) karyotype at a single center von Stephens, D M, Ruppert, A S, Jones, J A, Woyach, J, Maddocks, K, Jaglowski, S M, Andritsos, L A, Flynn, J M, Grever, M R, Lozanski, G, Johnson, A J, Muthusamy, N, Heerema, N A, Byrd, J C

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Phase I clinical and pharmacokinetic study of a novel schedule of flavopiridol in relapsed or refractory acute leukemias von BLUM, William, PHELPS, Mitch A, JOHNSON, Amy, SCHAAF, Larry J, BYRD, John C, MARCUCCI, Guido, GREVER, Michael R, KLISOVIC, Rebecca B, ROZEWSKI, Darlene M, WENJUN NI, ALBANESE, Katie A, ROVIN, Brad, KEFAUVER, Cheryl, DEVINE, Steven M, LUCAS, David M

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Immunoablative high-dose cyclophosphamide without stem cell rescue in paraneoplastic pemphigus: Report of a case and review of this new therapy for severe autoimmune disease von Nousari, Hossein C., Brodsky, Robert A., Jones, Richard J., Grever, Michael R., Anhalt, Grant J.

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The Taxol Supply Crisis. New NCI Policies for Handling the Large-Scale Production of Novel Natural Product Anticancer and Anti-HIV Agents von Cragg, Gordon M, Schepartz, Saul A, Suffness, Matthew, Grever, Michael R

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