High Fatality CBFA2T3-GLIS2 Pediatric Acute Megakaryoblastic Leukemia Is Sensitive to BCL-XL Inhibition von Gress, Verena, Roussy, Mathieu, Cardin, Sophie, Boulianne, Luc, Fatima, Furat, Laramée, Louise, Cheetham, Emma R., Rouette, Alexandre, Hachem, Nehme, Lisi, Véronique, Farah, Azer, Bilodeau, Melanie, Barabe, Frederic, Lavallée, Vincent-Philippe, Wilhelm, Brian T., Cellot, Sonia

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3093 – SUBTYPE-SPECIFIC INDUCTION OF MITOCHONDRIAL APOPTOSIS AS A NOVEL THERAPEUTIC OPTION IN HIGH-FATALITY PEDIATRIC LEUKEMIA von Gress, Verena, Cardin, Sophie, Roussy, Mathieu, Boulianne, Luc, Fatima, Furat, Laramee, Louise, Cheetham, Emma, Rouette, Alexandre, Hachem, Nehme, Bilodeau, Melanie, Wilhelm, Brian, Barabé, Frederic, Cellot, Sonia

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Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines von Safa-Tahar-Henni, Safia, Páez Martinez, Karla, Gress, Verena, Esparza, Nayeli, Roques, Élodie, Bonnet-Magnaval, Florence, Bilodeau, Mélanie, Gagné, Valérie, Bresson, Eva, Cardin, Sophie, El-Hachem, Nehme, Iasenza, Isabella, Alzial, Gabriel, Boivin, Isabel, Nakamichi, Naoto, Soufflet, Anne-Cécile, Mirela Pascariu, Cristina, Duchaine, Jean, Mathien, Simon, Bonneil, Éric, Eppert, Kolja, Marinier, Anne, Sauvageau, Guy, Deblois, Geneviève, Thibault, Pierre, Hébert, Josée, Eaves, Connie J, Cellot, Sonia, Barabé, Frédéric, Wilhelm, Brian T

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3173 – HUMAN MODELS OF PEDIATRIC CBFA2T3-GLIS2 ACUTE MEGAKARYOBLASTIC LEUKEMIA CONTRIBUTE TO UNCOVER THERAPEUTIC VULNERABILITIES von Roussy, Mathieu, Boulianne, Luc, Hachem, Nehme, Theret, Louis, Gress, Verena, Aubert, Léo, Bilodeau, Mélanie, Cardin, Sophie, Laramée, Louise, Lisi, Véronique, Rouette, Alexandre, Roux, Philippe, Lavallée, Vincent-Philippe, Cellot, Sonia

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Abstract P02: Uncovering Tailored Therapies for Acute Myeloid Leukemia in Children with Down Syndrome von Ta, Billy, Cheetham, Emma Rose, Cardin, Sophie, Gress, Verena, Soufflet, Anne-Cécile, Hachem, Nehme, Bilodeau, Melanie, Cellot, Sonia, Marmolejo, Carolina, Laramée, Louise

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Characterization of the T-cell receptor gamma chain gene rearrangements as an adjunct tool in the diagnosis of T-cell lymphomas in the gastrointestinal tract of cats von Gress, Verena, Wolfesberger, Birgitt, Fuchs-Baumgartinger, Andrea, Nedorost, Nora, Saalmüller, Armin, Schwendenwein, Ilse, Rütgen, Barbara C., Hammer, Sabine E.

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CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216 von Gress, Verena, Roussy, Mathieu, Boulianne, Luc, Bilodeau, Mélanie, Cardin, Sophie, El-Hachem, Nehme, Lisi, Véronique, Khakipoor, Banafsheh, Rouette, Alexandre, Farah, Azer, Théret, Louis, Aubert, Léo, Fatima, Furat, Audemard, Éric, Thibault, Pierre, Bonneil, Éric, Chagraoui, Jalila, Laramée, Louise, Gendron, Patrick, Jouan, Loubna, Jammali, Safa, Paré, Bastien, Simpson, Shawn M, Tran, Thai Hoa, Duval, Michel, Teira, Pierre, Bittencourt, Henrique, Santiago, Raoul, Barabé, Frédéric, Sauvageau, Guy, Smith, Martin A, Hébert, Josée, Roux, Philippe P, Gruber, Tanja A, Lavallée, Vincent-Philippe, Wilhelm, Brian T, Cellot, Sonia

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Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer von Hellebrand, Heide, Sutter, Christian, Honisch, Ellen, Gross, Eva, Wappenschmidt, Barbara, Schem, Christian, Deißler, Helmut, Ditsch, Nina, Gress, Verena, Kiechle, Marion, Bartram, Claus R., Schmutzler, Rita K., Niederacher, Dieter, Arnold, Norbert, Meindl, Alfons

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