Trends in industrialization of biotherapeutics: a survey of product characteristics of 89 antibody-based biotherapeutics von Martin, Kyle P., Grimaldi, Christine, Grempler, Rolf, Hansel, Steven, Kumar, Sandeep

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Short- and Longterm Glycemic Control of Streptozotocin-Induced Diabetic Rats Using Different Insulin Preparations von Luippold, Gerd, Bedenik, Jessica, Voigt, Anke, Grempler, Rolf

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Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors von Grempler, R., Thomas, L., Eckhardt, M., Himmelsbach, F., Sauer, A., Sharp, D. E., Bakker, R. A., Mark, M., Klein, T., Eickelmann, P.

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Empagliflozin, a novel potent and selective SGLT-2 inhibitor, improves glycaemic control alone and in combination with insulin in streptozotocin-induced diabetic rats, a model of t... von Luippold, G., Klein, T., Mark, M., Grempler, R.

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Characterization of Micro-RNA Changes during the Progression of Type 2 Diabetes in Zucker Diabetic Fatty Rats von Delic, Denis, Eisele, Claudia, Schmid, Ramona, Luippold, Gerd, Mayoux, Eric, Grempler, Rolf

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A reference map of potential determinants for the human serum metabolome von Bar, Noam, Korem, Tal, Weissbrod, Omer, Zeevi, David, Rothschild, Daphna, Leviatan, Sigal, Kosower, Noa, Lotan-Pompan, Maya, Weinberger, Adina, Le Roy, Caroline I., Menni, Cristina, Visconti, Alessia, Falchi, Mario, Spector, Tim D., Adamski, Jerzy, Franks, Paul W., Pedersen, Oluf, Segal, Eran

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Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK) von Grempler, Rolf, Wolff, Michael, Simon, Eric, Schmid, Ramona, Eisele, Claudia, Rieber, Kathrin, Fischer, Elke, Mettel, Sonja, Gabrielyan, Ogsen, Delic, Denis, Luippold, Gerd, Redeman, Norbert

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Courtly Representation Play, Singspiel, Opéra Comique. On the Reception of Antonio Sacchini’s 'L´isola d´amore' von Martina Grempler

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Analysis of Severe Elevated Thunderstorms over Frontal Surfaces Using DCIN and DCAPE von Market, Patrick, Grempler, Kevin, Sumrall, Paula, Henson, Chasity

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Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models von Allesøe, Rosa Lundbye, Lundgaard, Agnete Troen, Hernández Medina, Ricardo, Aguayo-Orozco, Alejandro, Johansen, Joachim, Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, Lili, Biel, Jorge Hernansanz, Leal Rodríguez, Cristina, Brasas, Valentas, Webel, Henry, Benros, Michael Eriksen, Pedersen, Anders Gorm, Chmura, Piotr Jaroslaw, Jacobsen, Ulrik Plesner, Mari, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Hong, Mun-Gwan, Musholt, Petra B., De Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, E. Louise, Frost, Gary, Thomsen, Henrik, Hansen, Elizaveta, Hansen, Tue Haldor, Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, Jane, Hattersley, Andrew, McDonald, Timothy, Ridderstråle, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Hansen, Torben, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, McCarthy, Mark I., Pearson, Ewan, Banasik, Karina, Rasmussen, Simon, Brunak, Søren

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A phase Ia/Ib, dose-escalation/expansion study of the MDM2–p53 antagonist BI 907828 in patients with solid tumors, including advanced/metastatic liposarcoma (LPS) von Gounder, Mrinal M., Yamamoto, Noboru, Patel, Manish R., Bauer, Todd Michael, Schöffski, Patrick, Grempler, Rolf, Durland-Busbice, Sara, Geng, Junxian, Maerten, Angela, LoRusso, Patricia

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Human Dose and Pharmacokinetic Predictions for Biologics at Boehringer Ingelheim: A Retrospective Analysis von Grempler, Rolf, Ahlberg, Jennifer, Germovsek, Eva, Gupta, Priyanka, Li, Hua, Pilvankar, Minu, Sharma, Ashish, Stopfer, Peter, Hansel, Steven

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Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter von Grempler, Rolf, Augustin, Robert, Froehner, Stefanie, Hildebrandt, Tobias, Simon, Eric, Mark, Michael, Eickelmann, Peter

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A phase I dose-escalation study of the MDM2-p53 antagonist BI 907828 in patients (pts) with advanced solid tumors von LoRusso, Patricia, Gounder, Mrinal M., Patel, Manish R., Yamamoto, Noboru, Bauer, Todd Michael, Laurie, Scott, Grempler, Rolf, Davenport, Teffany, Geng, Junxian, Rohrbacher, Maren, Lahmar, Mehdi

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Long-term treatment with empagliflozin, a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats von Thomas, L., Grempler, R., Eckhardt, M., Himmelsbach, F., Sauer, A., Klein, T., Eickelmann, P., Mark, M.

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The importance of choosing precipitation datasets von Simpson, Micheal J., Hirsch, Adam, Grempler, Kevin, Lupo, Anthony

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Abstract C047: A phase Ia/Ib, dose-escalation/expansion study of BI 907828, an MDM2-p53 antagonist, in combination with BI 754091, an anti-PD-1 antibody, and BI 754111, an anti-LAG... von Tolcher, Anthony, Hafez, Navid, Yamamoto, Noboru, Park, Jaehong, Grempler, Rolf, Lucarelli, Anthony, Vallaster, Markus P, Wang, Bushi, Hyman, David

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JS07.4.A A PHASE 0/IA STUDY OF BRIGIMADLIN CONCENTRATION IN BRAIN TISSUE AND A DOSE ESCALATION STUDY OF BRIGIMADLIN PLUS RADIOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA von Sarkaria, J N, Mrugala, M M, Jaeckle, K A, Burns, T C, Vaubel, R A, Parney, I F, Chaichana, K L, Clement, P M, Martínez-García, M, Sepúlveda Sanchez, J M, Omuro, A, Pronk, L, Ross, H, Teufel, M, Hesse, R, Grempler, R, Galanis, E

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A phase Ia/Ib, dose-escalation/expansion study of BI 907828 in combination with BI 754091 and BI 754111 in patients (pts) with advanced solid tumors von Tolcher, Anthony W., Hafez, Navid, Yamamoto, Noboru, Park, Jaehong, Grempler, Rolf, Lucarelli, Anthony G., Lahmar, Mehdi, Wang, Bushi, Gounder, Mrinal M.

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Design and rationale of the EMPA‐VISION trial: investigating the metabolic effects of empagliflozin in patients with heart failure von Hundertmark, Moritz J., Agbaje, Olorunsola F., Coleman, Ruth, George, Jyothis T., Grempler, Rolf, Holman, Rury R., Lamlum, Hanan, Lee, Jisoo, Milton, Joanne E., Niessen, Heiko G., Rider, Oliver, Rodgers, Christopher T., Valkovič, Ladislav, Wicks, Eleanor, Mahmod, Masliza, Neubauer, Stefan

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