The analysis of enzymic free energy relationships using kinetic and computational models von Greig, Ian R

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Tuning Mechanism-Based Inactivators of Neuraminidases: Mechanistic and Structural Insights von Buchini, Sabrina, Gallat, François-Xavier, Greig, Ian R., Kim, Jin-Hyo, Wakatsuki, Soichi, Chavas, Leonard M. G., Withers, Stephen G.

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Probing Synergy between Two Catalytic Strategies in the Glycoside Hydrolase O-GlcNAcase Using Multiple Linear Free Energy Relationships von Greig, Ian R, Macauley, Matthew S, Williams, Ian H, Vocadlo, David J

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Positive allosteric modulation of the cannabinoid CB1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics von Green, Hayley M., Manning, Jamie J., Greig, Ian R., Ross, Ruth A., Finlay, David B., Glass, Michelle

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Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics von Green, Hayley M, Manning, Jamie J, Greig, Ian R, Ross, Ruth A, Finlay, David B, Glass, Michelle

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Mechanism of glycoside hydrolysis: A comparative QM/MM molecular dynamics analysis for wild type and Y69F mutant retaining xylanases von Soliman, Mahmoud E S, Pernía, J Javier Ruiz, Greig, Ian R, Williams, Ian H

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Remarkable Reactivity Differences between Glucosides with Identical Leaving Groups von Duo, Tianmeng, Robinson, Kyle, Greig, Ian R, Chen, Hong-Ming, Patrick, Brian O, Withers, Stephen G

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Solvent Effects on Isotope Effects: Methyl Cation as a Model System von Wilson, Philippe B, Weaver, Paul J, Greig, Ian R, Williams, Ian H

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Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human O-GlcNAcase:  Mechanistic and Structural Insights into Inhibitor Selectivity and Transition State Pois... von Whitworth, Garrett E, Macauley, Matthew S, Stubbs, Keith A, Dennis, Rebecca J, Taylor, Edward J, Davies, Gideon J, Greig, Ian R, Vocadlo, David J

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Elucidating the Nature of the Streptomyces plicatus β-Hexosaminidase-Bound Intermediate Using ab initio Molecular Dynamics Simulations von Greig, Ian R, Zahariev, Federico, Withers, Stephen G

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Structural, Mechanistic, and Computational Analysis of the Effects of Anomeric Fluorines on Anomeric Fluoride Departure in 5-Fluoroxylosyl Fluorides von Lee, Seung Seo, Greig, Ian R, Vocadlo, David J, McCarter, John D, Patrick, Brian O, Withers, Stephen G

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Computational mutagenesis reveals the role of active-site tyrosine in stabilising a boat conformation for the substrate: QM/MM molecular dynamics studies of wild-type and mutant xy... von Soliman, Mahmoud E S, Ruggiero, Giuseppe D, Pernía, J Javier Ruiz, Greig, Ian R, Williams, Ian H

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Glycosidase inhibitors as conformational transition state analogues von Greig, Ian R, Williams, Ian H

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Synthesis of Cyclic Sulfonamides through Intramolecular Diels−Alder Reactions von Greig, Ian R, Tozer, Matthew J, Wright, Paul T

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Tuning Mechanism-Based Inactivators of Neuraminidases: Mechanistic and Structural Insights von Buchini, Sabrina, Gallat, François-Xavier, Greig, Ian R., Kim, Jin-Hyo, Wakatsuki, Soichi, Chavas, Leonard M. G., Withers, Stephen G.

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Synthesis of B2,5 type conformationally constrained glucopyranosides von Blériot, Yves, Vadivel, Subramanian K, Greig, Ian R, Kirby, Anthony J, Sinaÿ, Pierre

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Free energy relationships and intramolecular general acid catalysis von Greig, Ian R., Kirby, Anthony J.

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ChemInform Abstract: The Analysis of Enzymic Free Energy Relationships Using Kinetic and Computational Models von Greig, Ian R.

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Synthesis and acid catalyzed hydrolysis of B2,5 type conformationally constrained glucopyranosides: incorporation into a cellobiose analogue von Blériot, Yves, Vadivel, Subramanian K., Herrera, Antonio J., Greig, Ian R., Kirby, Anthony J., Sinaÿ, Pierre

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Synthesis and acid catalyzed hydrolysis of B 2,5 type conformationally constrained glucopyranosides: incorporation into a cellobiose analogue von Blériot, Yves, Vadivel, Subramanian K., Herrera, Antonio J., Greig, Ian R., Kirby, Anthony J., Sinaÿ, Pierre

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