Unique flexibility in energy metabolism allows mycobacteria to combat starvation and hypoxia von Berney, Michael, Cook, Gregory M

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A soil actinobacterium scavenges atmospheric H2 using two membrane-associated, oxygen-dependent [NiFe] hydrogenases von Greening, Chris, Berney, Michael, Hards, Kiel, Cook, Gregory M, Conrad, Ralf

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Diverse hydrogen production and consumption pathways influence methane production in ruminants von Greening, Chris, Geier, Renae, Wang, Cecilia, Woods, Laura C., Morales, Sergio E., McDonald, Michael J., Rushton-Green, Rowena, Morgan, Xochitl C., Koike, Satoshi, Leahy, Sinead C., Kelly, William J., Cann, Isaac, Attwood, Graeme T., Cook, Gregory M., Mackie, Roderick I.

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Ionophoric effects of the antitubercular drug bedaquiline von Hards, Kiel, McMillan, Duncan G. G., Schurig-Briccio, Lici A., Gennis, Robert B., Lilld, Holger, Bald, Dirk, Cook, Gregory M.

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CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis von McNeil, Matthew B, Keighley, Laura M, Cook, Josephine R, Cheung, Chen-Yi, Cook, Gregory M

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obligately aerobic soil bacterium activates fermentative hydrogen production to survive reductive stress during hypoxia von Berney, Michael, Greening, Chris, Conrad, Ralf, Jacob, William R., Cook, Gregory M.

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The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis von Waller, Natalie J. E., Cheung, Chen-Yi, Cook, Gregory M., McNeil, Matthew B.

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Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection von Hasenoehrl, Erik J., Rae Sajorda, Dannah, Berney-Meyer, Linda, Johnson, Samantha, Tufariello, JoAnn M., Fuhrer, Tobias, Cook, Gregory M., Jacobs, William R., Berney, Michael

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Impaired Succinate Oxidation Prevents Growth and Influences Drug Susceptibility in Mycobacterium tuberculosis von Adolph, Cara, McNeil, Matthew B., Cook, Gregory M.

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Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering von Lee, Brendon M., Harold, Liam K., Almeida, Deepak V., Afriat-Jurnou, Livnat, Aung, Htin Lin, Forde, Brian M., Hards, Kiel, Pidot, Sacha J., Ahmed, F. Hafna, Mohamed, A. Elaaf, Taylor, Matthew C., West, Nicholas P., Stinear, Timothy P., Greening, Chris, Beatson, Scott A., Nuermberger, Eric L., Cook, Gregory M., Jackson, Colin J.

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Deciphering functional redundancy and energetics of malate oxidation in mycobacteria von Harold, Liam K., Jinich, Adrian, Hards, Kiel, Cordeiro, Alexandra, Keighley, Laura M., Cross, Alec, McNeil, Matthew B., Rhee, Kyu, Cook, Gregory M.

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The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress von Lu, Ping, Heineke, Marieke H., Koul, Anil, Andries, Koen, Cook, Gregory M., Lill, Holger, van Spanning, Rob, Bald, Dirk

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The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB von Safarian, Schara, Opel-Reading, Helen K., Wu, Di, Mehdipour, Ahmad R., Hards, Kiel, Harold, Liam K., Radloff, Melanie, Stewart, Ian, Welsch, Sonja, Hummer, Gerhard, Cook, Gregory M., Krause, Kurt L., Michel, Hartmut

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Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis von Lee, Bei Shi, Hards, Kiel, Engelhart, Curtis A, Hasenoehrl, Erik J, Kalia, Nitin P, Mackenzie, Jared S, Sviriaeva, Ekaterina, Chong, Shi Min Sherilyn, Manimekalai, Malathy Sony S, Koh, Vanessa H, Chan, John, Xu, Jiayong, Alonso, Sylvie, Miller, Marvin J, Steyn, Adrie J C, Grüber, Gerhard, Schnappinger, Dirk, Berney, Michael, Cook, Gregory M, Moraski, Garrett C, Pethe, Kevin

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Atmospheric hydrogen scavenging: from enzymes to ecosystems von Greening, Chris, Constant, Philippe, Hards, Kiel, Morales, Sergio E, Oakeshott, John G, Russell, Robyn J, Taylor, Matthew C, Berney, Michael, Conrad, Ralf, Cook, Gregory M

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M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments von Kalia, Nitin Pal, Singh, Samsher, Hards, Kiel, Cheung, Chen-Yi, Sviriaeva, Ekaterina, Banaei-Esfahani, Amir, Aebersold, Ruedi, Berney, Michael, Cook, Gregory M., Pethe, Kevin

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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus von Pidot, Sacha J, Klatt, Stephan, Ates, Louis S, Frigui, Wafa, Sayes, Fadel, Majlessi, Laleh, Izumi, Hiroshi, Monk, Ian R, Porter, Jessica L, Bennett-Wood, Vicki, Seemann, Torsten, Otter, Ashley, Taiaroa, George, Cook, Gregory M, West, Nicholas, Tobias, Nicholas J, Fuerst, John A, Stutz, Michael D, Pellegrini, Marc, McConville, Malcolm, Brosch, Roland, Stinear, Timothy P

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Mycobacterium smegmatis Resists the Bactericidal Activity of Hypochlorous Acid Produced in Neutrophil Phagosomes von Parker, Heather A., Dickerhof, Nina, Forrester, Lorna, Ryburn, Heath, Smyth, Leon, Messens, Joris, Aung, Htin L., M Cook, Gregory, Kettle, Anthony J., Hampton, Mark B.

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Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis von Wang, XinYue, Jowsey, William J., Cheung, Chen-Yi, Smart, Caitlan J., Klaus, Hannah R., Seeto, Noon EJ, Waller, Natalie JE, Chrisp, Michael T., Peterson, Amanda L., Ofori-Anyinam, Boatema, Strong, Emily, Nijagal, Brunda, West, Nicholas P., Yang, Jason H., Fineran, Peter C., Cook, Gregory M., Jackson, Simon A., McNeil, Matthew B.

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Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion von Allen, William J, Corey, Robin A, Watkins, Daniel W, Oliveira, A Sofia F, Hards, Kiel, Cook, Gregory M, Collinson, Ian

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