Targeting ALK: Precision Medicine Takes on Drug Resistance von Lin, Jessica J, Riely, Gregory J, Shaw, Alice T

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New Pathologic Classification of Lung Cancer: Relevance for Clinical Practice and Clinical Trials von Travis, William D, Brambilla, Elisabeth, Riely, Gregory J

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Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update von Hanna, Nasser, Johnson, David, Temin, Sarah, Baker, Jr, Sherman, Brahmer, Julie, Ellis, Peter M, Giaccone, Giuseppe, Hesketh, Paul J, Jaiyesimi, Ishmael, Leighl, Natasha B, Riely, Gregory J, Schiller, Joan H, Schneider, Bryan J, Smith, Thomas J, Tashbar, Joan, Biermann, William A, Masters, Gregory

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Alectinib in ALK -positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial von Shaw, Alice T, Dr, Gandhi, Leena, MD, Gadgeel, Shirish, Prof, Riely, Gregory J, MD, Cetnar, Jeremy, MD, West, Howard, MD, Camidge, D Ross, MD, Socinski, Mark A, Prof, Chiappori, Alberto, MD, Mekhail, Tarek, MD, Chao, Bo H, MD, Borghaei, Hossein, DO, Gold, Kathryn A, MD, Zeaiter, Ali, MD, Bordogna, Walter, PhD, Balas, Bogdana, MD, Puig, Oscar, PhD, Henschel, Volkmar, PhD, Ou, Sai-Hong Ignatius, Prof

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Lorlatinib in advanced ROS1-positive non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 1–2 trial von Shaw, Alice T, Solomon, Benjamin J, Chiari, Rita, Riely, Gregory J, Besse, Benjamin, Soo, Ross A, Kao, Steven, Lin, Chia-Chi, Bauer, Todd M, Clancy, Jill S, Thurm, Holger, Martini, Jean-Francois, Peltz, Gerson, Abbattista, Antonello, Li, Sherry, Ou, Sai-Hong Ignatius

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Therapy for Stage IV Non-Small-Cell Lung Cancer Without Driver Alterations: ASCO and OH (CCO) Joint Guideline Update von Hanna, Nasser H, Schneider, Bryan J, Temin, Sarah, Baker, Jr, Sherman, Brahmer, Julie, Ellis, Peter M, Gaspar, Laurie E, Haddad, Rami Y, Hesketh, Paul J, Jain, Dharamvir, Jaiyesimi, Ishmael, Johnson, David H, Leighl, Natasha B, Phillips, Tanyanika, Riely, Gregory J, Robinson, Andrew G, Rosell, Rafael, Schiller, Joan H, Singh, Navneet, Spigel, David R, Stabler, Janis O, Tashbar, Joan, Masters, Gregory

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Tumor mutational load predicts survival after immunotherapy across multiple cancer types von Samstein, Robert M., Lee, Chung-Han, Shoushtari, Alexander N., Hellmann, Matthew D., Shen, Ronglai, Janjigian, Yelena Y., Barron, David A., Zehir, Ahmet, Jordan, Emmet J., Omuro, Antonio, Kaley, Thomas J., Kendall, Sviatoslav M., Motzer, Robert J., Hakimi, A. Ari, Voss, Martin H., Russo, Paul, Rosenberg, Jonathan, Iyer, Gopa, Bochner, Bernard H., Bajorin, Dean F., Al-Ahmadie, Hikmat A., Chaft, Jamie E., Rudin, Charles M., Riely, Gregory J., Baxi, Shrujal, Ho, Alan L., Wong, Richard J., Pfister, David G., Wolchok, Jedd D., Barker, Christopher A., Gutin, Philip H., Brennan, Cameron W., Tabar, Viviane, Mellinghoff, Ingo K., DeAngelis, Lisa M., Ariyan, Charlotte E., Lee, Nancy, Tap, William D., Gounder, Mrinal M., D’Angelo, Sandra P., Saltz, Leonard, Stadler, Zsofia K., Scher, Howard I., Baselga, Jose, Razavi, Pedram, Klebanoff, Christopher A., Yaeger, Rona, Segal, Neil H., Ku, Geoffrey Y., DeMatteo, Ronald P., Ladanyi, Marc, Rizvi, Naiyer A., Berger, Michael F., Riaz, Nadeem, Solit, David B., Chan, Timothy A., Morris, Luc G. T.

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Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients von Nguyen, Bastien, Fong, Christopher, Luthra, Anisha, Smith, Shaleigh A., DiNatale, Renzo G., Nandakumar, Subhiksha, Walch, Henry, Chatila, Walid K., Madupuri, Ramyasree, Kundra, Ritika, Bielski, Craig M., Mastrogiacomo, Brooke, Donoghue, Mark T.A., Boire, Adrienne, Chandarlapaty, Sarat, Ganesh, Karuna, Harding, James J., Iacobuzio-Donahue, Christine A., Razavi, Pedram, Reznik, Ed, Rudin, Charles M., Zamarin, Dmitriy, Abida, Wassim, Abou-Alfa, Ghassan K., Aghajanian, Carol, Cercek, Andrea, Chi, Ping, Feldman, Darren, Ho, Alan L., Iyer, Gopakumar, Janjigian, Yelena Y., Morris, Michael, Motzer, Robert J., O’Reilly, Eileen M., Postow, Michael A., Raj, Nitya P., Riely, Gregory J., Robson, Mark E., Rosenberg, Jonathan E., Safonov, Anton, Shoushtari, Alexander N., Tap, William, Teo, Min Yuen, Varghese, Anna M., Voss, Martin, Yaeger, Rona, Zauderer, Marjorie G., Abu-Rustum, Nadeem, Garcia-Aguilar, Julio, Bochner, Bernard, Hakimi, Abraham, Jarnagin, William R., Jones, David R., Molena, Daniela, Morris, Luc, Rios-Doria, Eric, Russo, Paul, Singer, Samuel, Strong, Vivian E., Chakravarty, Debyani, Ellenson, Lora H., Gopalan, Anuradha, Reis-Filho, Jorge S., Weigelt, Britta, Ladanyi, Marc, Gonen, Mithat, Shah, Sohrab P., Massague, Joan, Gao, Jianjiong, Zehir, Ahmet, Berger, Michael F., Solit, David B., Bakhoum, Samuel F., Sanchez-Vega, Francisco, Schultz, Nikolaus

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ALK Resistance Mutations and Efficacy of Lorlatinib in Advanced Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer von Shaw, Alice T, Solomon, Benjamin J, Besse, Benjamin, Bauer, Todd M, Lin, Chia-Chi, Soo, Ross A, Riely, Gregory J, Ou, Sai-Hong Ignatius, Clancy, Jill S, Li, Sherry, Abbattista, Antonello, Thurm, Holger, Satouchi, Miyako, Camidge, D Ross, Kao, Steven, Chiari, Rita, Gadgeel, Shirish M, Felip, Enriqueta, Martini, Jean-François

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Antitumor activity of crizotinib in lung cancers harboring a MET exon 14 alteration von Drilon, Alexander, Clark, Jeffrey W., Weiss, Jared, Ou, Sai-Hong Ignatius, Camidge, D. Ross, Solomon, Benjamin J., Otterson, Gregory A., Villaruz, Liza C., Riely, Gregory J., Heist, Rebecca S., Awad, Mark M., Shapiro, Geoffrey I., Satouchi, Miyako, Hida, Toyoaki, Hayashi, Hidetoshi, Murphy, Danielle A., Wang, Sherry C., Li, Sherry, Usari, Tiziana, Wilner, Keith D., Paik, Paul K.

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Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes von Offin, Michael, Chan, Joseph M., Tenet, Megan, Rizvi, Hira A., Shen, Ronglai, Riely, Gregory J., Rekhtman, Natasha, Daneshbod, Yahya, Quintanal-Villalonga, Alvaro, Penson, Alexander, Hellmann, Matthew D., Arcila, Maria E., Ladanyi, Marc, Pe’er, Dana, Kris, Mark G., Rudin, Charles M., Yu, Helena A.

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High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants von Razavi, Pedram, Li, Bob T., Brown, David N., Jung, Byoungsok, Hubbell, Earl, Shen, Ronglai, Abida, Wassim, Juluru, Krishna, De Bruijn, Ino, Hou, Chenlu, Venn, Oliver, Lim, Raymond, Anand, Aseem, Maddala, Tara, Gnerre, Sante, Vijaya Satya, Ravi, Liu, Qinwen, Shen, Ling, Eattock, Nicholas, Yue, Jeanne, Blocker, Alexander W., Lee, Mark, Sehnert, Amy, Xu, Hui, Hall, Megan P., Santiago-Zayas, Angie, Novotny, William F., Isbell, James M., Rusch, Valerie W., Plitas, George, Heerdt, Alexandra S., Ladanyi, Marc, Hyman, David M., Jones, David R., Morrow, Monica, Riely, Gregory J., Scher, Howard I., Rudin, Charles M., Robson, Mark E., Diaz, Luis A., Solit, David B., Aravanis, Alexander M., Reis-Filho, Jorge S.

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EGFR: The Paradigm of an Oncogene-Driven Lung Cancer von Riely, Gregory J, Yu, Helena A

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Cabozantinib in patients with advanced RET -rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial von Drilon, Alexander, Dr, Rekhtman, Natasha, PhD, Arcila, Maria, MD, Wang, Lu, PhD, Ni, Andy, PhD, Albano, Melanie, Van Voorthuysen, Martine, Somwar, Romel, PhD, Smith, Roger S, Montecalvo, Joseph, MD, Plodkowski, Andrew, MD, Ginsberg, Michelle S, MD, Riely, Gregory J, PhD, Rudin, Charles M, Prof, Ladanyi, Marc, Prof, Kris, Mark G, Prof

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SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas von Rekhtman, Natasha, Montecalvo, Joseph, Chang, Jason C., Alex, Deepu, Ptashkin, Ryan N., Ai, Ni, Sauter, Jennifer L., Kezlarian, Brie, Jungbluth, Achim, Desmeules, Patrice, Beras, Amanda, Bishop, Justin A., Plodkowski, Andrew J., Gounder, Mrinal M., Schoenfeld, Adam J., Namakydoust, Azadeh, Li, Bob T., Rudin, Charles M., Riely, Gregory J., Jones, David R., Ladanyi, Marc, Travis, William D.

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Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer von Shaw, Alice T, Ou, Sai-Hong I, Bang, Yung-Jue, Camidge, D. Ross, Solomon, Benjamin J, Salgia, Ravi, Riely, Gregory J, Varella-Garcia, Marileila, Shapiro, Geoffrey I, Costa, Daniel B, Doebele, Robert C, Le, Long Phi, Zheng, Zongli, Tan, Weiwei, Stephenson, Patricia, Shreeve, S. Martin, Tye, Lesley M, Christensen, James G, Wilner, Keith D, Clark, Jeffrey W, Iafrate, A. John

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Clinical Characteristics of Patients With Lung Adenocarcinomas Harboring BRAF Mutations von PAIK, Paul K, ARCILA, Maria E, FARA, Michael, SIMA, Camelia S, MILLER, Vincent A, KRIS, Mark G, LADANYI, Marc, RIELY, Gregory J

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Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK -rearranged non-small-cell lung cancer (AF-002JG): results... von Gadgeel, Shirish M, MD, Gandhi, Leena, MD, Riely, Gregory J, MD, Chiappori, Alberto A, MD, West, Howard L, MD, Azada, Michele C, MPH, Morcos, Peter N, PharmD, Lee, Ruey-Min, MD, Garcia, Linta, PharmD, Yu, Li, PhD, Boisserie, Frederic, MSc, Di Laurenzio, Laura, PhD, Golding, Sophie, MSc, Sato, Jotaro, MS, Yokoyama, Shumpei, MS, Tanaka, Tomohiro, MS, Ou, Sai-Hong Ignatius, Dr

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Therapy for Stage IV Non-Small-Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline von Singh, Navneet, Temin, Sarah, Baker, Jr, Sherman, Blanchard, Elizabeth, Brahmer, Julie R, Celano, Paul, Duma, Narjust, Ellis, Peter M, Elkins, Ivy B, Haddad, Rami Y, Hesketh, Paul J, Jain, Dharamvir, Johnson, David H, Leighl, Natasha B, Mamdani, Hirva, Masters, Gregory, Moffitt, Pamela R, Phillips, Tanyanika, Riely, Gregory J, Robinson, Andrew G, Rosell, Rafael, Schiller, Joan H, Schneider, Bryan J, Spigel, David R, Jaiyesimi, Ishmael A

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Impact of proposed IASLC ATS ERS classification of lung adenocarcinoma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases von Yoshizawa, Akihiko, Motoi, Noriko, Riely, Gregory J, Sima, Cami S, Gerald, William L, Kris, Mark G, Park, Bernard J, Rusch, Valerie W, Travis, William D

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