An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme von Ceccarelli, Derek F., Tang, Xiaojing, Pelletier, Benoit, Orlicky, Stephen, Xie, Weilin, Plantevin, Veronique, Neculai, Dante, Chou, Yang-Chieh, Ogunjimi, Abiodun, Al-Hakim, Abdallah, Varelas, Xaralabos, Koszela, Joanna, Wasney, Gregory A., Vedadi, Masoud, Dhe-Paganon, Sirano, Cox, Sarah, Xu, Shuichan, Lopez-Girona, Antonia, Mercurio, Frank, Wrana, Jeff, Durocher, Daniel, Meloche, Sylvain, Webb, David R., Tyers, Mike, Sicheri, Frank

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Recognition and Specificity Determinants of the Human Cbx Chromodomains von Kaustov, Lilia, Ouyang, Hui, Amaya, Maria, Lemak, Alexander, Nady, Nataliya, Duan, Shili, Wasney, Gregory A., Li, Zhihong, Vedadi, Masoud, Schapira, Matthieu, Min, Jinrong, Arrowsmith, Cheryl H.

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Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers von Rujas, Edurne, Kucharska, Iga, Tan, Yong Zi, Benlekbir, Samir, Cui, Hong, Zhao, Tiantian, Wasney, Gregory A., Budylowski, Patrick, Guvenc, Furkan, Newton, Jocelyn C., Sicard, Taylor, Semesi, Anthony, Muthuraman, Krithika, Nouanesengsy, Amy, Aschner, Clare Burn, Prieto, Katherine, Bueler, Stephanie A., Youssef, Sawsan, Liao-Chan, Sindy, Glanville, Jacob, Christie-Holmes, Natasha, Mubareka, Samira, Gray-Owen, Scott D., Rubinstein, John L., Treanor, Bebhinn, Julien, Jean-Philippe

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Delineating Structural Propensities of the 4E-BP2 Protein via Integrative Modeling and Clustering von Tsangaris, Thomas E., Smyth, Spencer, Gomes, Gregory-Neal W., Liu, Zi Hao, Milchberg, Moses, Bah, Alaji, Wasney, Gregory A., Forman-Kay, Julie D., Gradinaru, Claudiu C.

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Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 von Senisterra, Guillermo, Wu, Hong, Allali-Hassani, Abdellah, Wasney, Gregory A, Barsyte-Lovejoy, Dalia, Dombrovski, Ludmila, Dong, Aiping, Nguyen, Kong T, Smil, David, Bolshan, Yuri, Hajian, Taraneh, He, Hao, Seitova, Alma, Chau, Irene, Li, Fengling, Poda, Gennadiy, Couture, Jean-François, Brown, Peter J, Al-Awar, Rima, Schapira, Matthieu, Arrowsmith, Cheryl H, Vedadi, Masoud

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Chemical Screening Methods to Identify Ligands That Promote Protein Stability, Protein Crystallization, and Structure Determination von Vedadi, Masoud, Niesen, Frank H., Allali-Hassani, Abdellah, Fedorov, Oleg Y., Finerty, Patrick J., Wasney, Gregory A., Yeung, Ron, Arrowsmith, Cheryl, Ball, Linda J., Berglund, Helena, Hui, Raymond, Marsden, Brian D., Nordlund, Pär, Sundstrom, Michael, Weigelt, Johan, Edwards, Aled M.

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Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance von Sobhanifar, Solmaz, Worrall, Liam J, King, Dustin T, Wasney, Gregory A, Baumann, Lars, Gale, Robert T, Nosella, Michael, Brown, Eric D, Withers, Stephen G, Strynadka, Natalie C J

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An Allosteric Inhibitor of Protein Arginine Methyltransferase 3 von Siarheyeva, Alena, Senisterra, Guillermo, Allali-Hassani, Abdellah, Dong, Aiping, Dobrovetsky, Elena, Wasney, Gregory A., Chau, Irene, Marcellus, Richard, Hajian, Taraneh, Liu, Feng, Korboukh, Ilia, Smil, David, Bolshan, Yuri, Min, Jinrong, Wu, Hong, Zeng, Hong, Loppnau, Peter, Poda, Gennadiy, Griffin, Carly, Aman, Ahmed, Brown, Peter J., Jin, Jian, Al-awar, Rima, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud

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Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a von Liu, Feng, Chen, Xin, Allali-Hassani, Abdellah, Quinn, Amy M, Wasney, Gregory A, Dong, Aiping, Barsyte, Dalia, Kozieradzki, Ivona, Senisterra, Guillermo, Chau, Irene, Siarheyeva, Alena, Kireev, Dmitri B, Jadhav, Ajit, Herold, J. Martin, Frye, Stephen V, Arrowsmith, Cheryl H, Brown, Peter J, Simeonov, Anton, Vedadi, Masoud, Jin, Jian

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The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body von Bergeron, Julien R.C., Worrall, Liam J., De, Soumya, Sgourakis, Nikolaos G., Cheung, Adrienne H., Lameignere, Emilie, Okon, Mark, Wasney, Gregory A., Baker, David, McIntosh, Lawrence P., Strynadka, Natalie C.J.

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Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid α-glycosyltransferase von Sobhanifar, Solmaz, Worrall, Liam James, Gruninger, Robert J, Wasney, Gregory A, Blaukopf, Markus, Baumann, Lars, Lameignere, Emilie, Solomonson, Matthew, Brown, Eric D, Withers, Stephen G, Strynadka, Natalie C J

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Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines von Liu, Feng, Chen, Xin, Allali-Hassani, Abdellah, Quinn, Amy M, Wigle, Tim J, Wasney, Gregory A, Dong, Aiping, Senisterra, Guillermo, Chau, Irene, Siarheyeva, Alena, Norris, Jacqueline L, Kireev, Dmitri B, Jadhav, Ajit, Herold, J. Martin, Janzen, William P, Arrowsmith, Cheryl H, Frye, Stephen V, Brown, Peter J, Simeonov, Anton, Vedadi, Masoud, Jin, Jian

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The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing von Bergeron, Julien R.C., Fernández, Lucia, Wasney, Gregory A., Vuckovic, Marija, Reffuveille, Fany, Hancock, Robert E.W., Strynadka, Natalie C.J.

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Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12 von Chen, Zhuoyao, Wasney, Gregory A, Picaud, Sarah, Filippakopoulos, Panagis, Vedadi, Masoud, D'Angiolella, Vincenzo, Bullock, Alex N

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Polyphosphate suppresses complement via the terminal pathway von Wat, Jovian M., Foley, Jonathan H., Krisinger, Michael J., Ocariza, Linnette Mae, Lei, Victor, Wasney, Gregory A., Lameignere, Emilie, Strynadka, Natalie C., Smith, Stephanie A., Morrissey, James H., Conway, Edward M.

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Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2 von Adams-Cioaba, Melanie A, Guo, Yahong, Bian, ChuanBing, Amaya, Maria F, Lam, Robert, Wasney, Gregory A, Vedadi, Masoud, Xu, Chao, Min, Jinrong

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Small Molecule Inhibition of an Exopolysaccharide Modification Enzyme is a Viable Strategy To Block Pseudomonas aeruginosa Pel Biofilm Formation von Razvi, Erum, DiFrancesco, Benjamin R, Wasney, Gregory A, Morrison, Zachary A, Tam, John, Auger, Anick, Baker, Perrin, Alnabelseya, Noor, Rich, Jacquelyn D, Sivarajah, Piyanka, Whitfield, Gregory B, Harrison, Joe J, Melnyk, Roman A, Nitz, Mark, Howell, P Lynne

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Biophysical characterization of recombinant proteins: A key to higher structural genomics success von Vedadi, Masoud, Arrowsmith, Cheryl H., Allali-Hassani, Abdellah, Senisterra, Guillermo, Wasney, Gregory A.

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Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms von Vedadi, Masoud, Lew, Jocelyne, Artz, Jennifer, Amani, Mehrnaz, Zhao, Yong, Dong, Aiping, Wasney, Gregory A., Gao, Mian, Hills, Tanya, Brokx, Stephen, Qiu, Wei, Sharma, Sujata, Diassiti, Angelina, Alam, Zahoor, Melone, Michelle, Mulichak, Anne, Wernimont, Amy, Bray, James, Loppnau, Peter, Plotnikova, Olga, Newberry, Kate, Sundararajan, Emayavaram, Houston, Simon, Walker, John, Tempel, Wolfram, Bochkarev, Alexey, Kozieradzki, Ivona, Edwards, Aled, Arrowsmith, Cheryl, Roos, David, Kain, Kevin, Hui, Raymond

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Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system von Zhang, Heng, Dong, Cheng, Li, Li, Wasney, Gregory A, Min, Jinrong

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