Pulmonary type2 innate lymphoid cells in paediatric severe asthma: phenotype and response to steroids von Nagakumar, P, Puttur, F, Gregory, LG, Denney, L, Fleming, L, Bush, A, Lloyd, CM, Saglani, S

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A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies ANXA1 as a susceptibility locus for persistent wheezing von Granell, R, Curtin, JA, Haider, S, Kitaba, NT, Mathie, SA, Gregory, LG, Yates, LL, Tutino, M, Hankinson, J, Perretti, M, Vonk, JM, Arshad, HS, Cullinan, P, Fontanella, S, Roberts, GC, Koppelman, GH, Simpson, A, Turner, SW, Murray, CS, Lloyd, CM, Holloway, JW, Custovic, A, UNICORN and Breathing Together investigators

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Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero von PEEBLES, D, GREGORY, L. G, RODECK, C, COUTELLE, C, DAVID, A, THEMIS, M, WADDINGTON, S. N, KNAPTON, H. J, MIAH, M, COOK, T, LAWRENCE, L, NIVSARKAR, M

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Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection von Peiró, T, Patel, DF, Akthar, S, Gregory, LG, Pyle, CJ, Harker, JA, Birrell, MA, LLoyd, CM, Snelgrove, RJ

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Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice von Themis, Mike, Waddington, Simon N, Schmidt, Manfred, von Kalle, Christof, Wang, Yoahe, Al-Allaf, Faisal, Gregory, Lisa G, Nivsarkar, Megha, Themis, Matthew, Holder, Maxine V, Buckley, Suzanne M K, Dighe, Niraja, Ruthe, Alaine T, Mistry, Ajay, Bigger, Brian, Rahim, Ahad, Nguyen, Tuan H, Trono, Didier, Thrasher, Adrian J, Coutelle, Charles

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Pulmonary ORMDL3 is critical for induction of Alternaria induced allergic airways disease von Löser, S, Gregory, LG, Zhang, Y, Schaefer, K, Walker, SA, Buckley, J, Denney, L, Dean, CH, Cookson, WO, Moffatt, MF, Lloyd, CM

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Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model von Gregory, LG, Jones, CP, Mathie, SA, Pegorier, S, Lloyd, CM

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Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge von Mathie, SA, Dixon, KL, Walker, SA, Tyrrell, V, Mondhe, M, O'Donnell, VB, Gregory, LG, Lloyd, CM

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Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations von Snelgrove, RJ, Gregory, LG, Peiro, T, Akthar, S, Campbell, GA, Walker, SA, Lloyd, CM

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Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life von Lee, DC, Walker, SA, Byrne, AJ, Gregory, LG, Buckley, J, Bush, A, Shaheen, SO, Saglani, S, Lloyd, CM

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Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy von Waddington, Simon N., Nivsarkar, Megha S., Mistry, Ajay R., Buckley, Suzanne M.K., Kemball-Cook, Geoffrey, Mosley, Karen L., Mitrophanous, Kyriacos, Radcliffe, Pippa, Holder, Maxine V., Brittan, Mairi, Georgiadis, Anastasios, Al-Allaf, Faisal, Bigger, Brian W., Gregory, Lisa G., Cook, H. Terence, Ali, Robin R., Thrasher, Adrian, Tuddenham, Edward G.D., Themis, Mike, Coutelle, Charles

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Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33 von Castanhinha, S, Sherburn, RT, Walker, SA, Gupta, A, Bossley, CJ, Buckley, J, Ullmann, N, Grychtol, R, Campbell, GA, Maglione, M, Koo, S, Fleming, LJ, Gregory, LG, Snelgrove, RJ, Bush, AJ, Lloyd, CM, Saglani, S

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IL-25 drives remodelling in allergic airways disease induced by house dust mite von Gregory, LG, Jones, CP, Walker, SA, Sawant, D, Gowers, KHC, Campbell, GA, McKenzie, ANJ, Lloyd, CM

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Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte-dendritic cell antigen presentation von Patel, DF, Peiro, T, Bruno, N, Vuononvirta, J, Akthar, S, Puttur, F, Pyle, CJ, Suveizdyte, K, Walker, SA, Singanayagam, A, Carlin, LM, Gregory, LG, Lloyd, CM, Snelgrove, R

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Inception of early life allergen induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells von Saglani, S, Gregory, LG, Manghera, AK, Branchett, WJ, Uwadiae, F, Entwistle, LJ, Oliver, RA, Vasiliou, JE, Sherburn, R, Lui, S, Puttur, F, Voehringer, D, Walker, SA, Buckley, J, Grychtol, R, Fainardi, V, Denney, L, Byrnes, A, Von Mutius, E, Bush, A, Lloyd, CM

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Characterization of a nitrate-respiring bacterial community using the nitrate reductase gene (narG) as a functional marker von Gregory, Lisa G, Bond, Philip L, Richardson, David J, Spiro, Stephen

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Gene Therapy Progress and Prospects: Fetal gene therapy - first proofs of concept - some adverse effects von COUTELLE, C, THEMIS, M, WADDINGTON, S. N, BUCKLEY, S. M. K, GREGORY, L. G, NIVSARKAR, M. S, DAVID, A. L, PEEBLES, D, WEISZ, B, RODECK, C

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Fetal and neonatal gene therapy: benefits and pitfalls von Waddington, S N, Kennea, N L, Buckley, S M K, Gregory, L G, Themis, M, Coutelle, C

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Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo von Gregory, Lisa G, Harbottle, Richard P, Lawrence, Lorraine, Knapton, Holly J, Themis, Michael, Coutelle, Charles

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Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy von GREGORY, L. G, WADDINGTON, S. N, AL-ALLAF, F, KINGSMAN, S, COUTELLE, C, THEMIS, M, HOLDER, M. V, MITROPHANOUS, K. A, BUCKLEY, S. M. K, MOSLEY, K. L, BIGGER, B. W, ELLARD, F. M, WALMSLEY, L. E, LAWRENCE, L

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