OpenMI: Open modelling interface von Gregersen, J B, Gijsbers, P J A, Westen, S J P

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Towards an Open Modelling Interface (OpenMI) the HarmonIT project von Blind, M, Gregersen, J. B

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OpenMI: the essential concepts and their implications for legacy software von Gregersen, J. B, Gijsbers, P. J. A, Westen, S. J. P, Blind, M

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Leading Strategic Change: Breaking Through the Brain Barrier von J. Stewart Black, Hal B. Gregersen

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Interferon-Inducible Gene Expression Signature in Peripheral Blood Cells of Patients with Severe Lupus von Baechler, Emily C., Batliwalla, Franak M., Karypis, George, Gaffney, Patrick M., Ortmann, Ward A., Espe, Karl J., Shark, Katherine B., Grande, William J., Hughes, Karis M., Kapur, Vivek, Gregersen, Peter K., Behrens, Timothy W.

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Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity von Han, Buhm, Diogo, Dorothée, Eyre, Steve, Kallberg, Henrik, Zhernakova, Alexandra, Bowes, John, Padyukov, Leonid, Okada, Yukinori, González-Gay, Miguel A., Rantapää-Dahlqvist, Solbritt, Martin, Javier, Huizinga, Tom W.J., Plenge, Robert M., Worthington, Jane, Gregersen, Peter K., Klareskog, Lars, de Bakker, Paul I.W., Raychaudhuri, Soumya

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Quantifying missing heritability at known GWAS loci von Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J, Diogo, Dorothée, Stahl, Eli A, Gregersen, Peter K, Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M, Pasaniuc, Bogdan, Price, Alkes L

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Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production von Chung, Sharon A, Taylor, Kimberly E, Graham, Robert R, Nititham, Joanne, Lee, Annette T, Ortmann, Ward A, Jacob, Chaim O, Alarcón-Riquelme, Marta E, Tsao, Betty P, Harley, John B, Gaffney, Patrick M, Moser, Kathy L, Petri, Michelle, Demirci, F Yesim, Kamboh, M Ilyas, Manzi, Susan, Gregersen, Peter K, Langefeld, Carl D, Behrens, Timothy W, Criswell, Lindsey A

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Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes von Miller, F W, Chen, W, O'Hanlon, T P, Cooper, R G, Vencovsky, J, Rider, L G, Danko, K, Wedderburn, L R, Lundberg, I E, Pachman, L M, Reed, A M, Ytterberg, S R, Padyukov, L, Selva-O'Callaghan, A, Radstake, T R, Isenberg, D A, Chinoy, H, Ollier, W E R, Scheet, P, Peng, B, Lee, A, Byun, J, Lamb, J A, Gregersen, P K, Amos, C I

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Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase von Olofsson, Peder S, Steinberg, Benjamin E, Sobbi, Roozbeh, Cox, Maureen A, Ahmed, Mohamed N, Oswald, Michaela, Szekeres, Ferenc, Hanes, William M, Introini, Andrea, Liu, Shu Fang, Holodick, Nichol E, Rothstein, Thomas L, Lövdahl, Cecilia, Chavan, Sangeeta S, Yang, Huan, Pavlov, Valentin A, Broliden, Kristina, Andersson, Ulf, Diamond, Betty, Miller, Edmund J, Arner, Anders, Gregersen, Peter K, Backx, Peter H, Mak, Tak W, Tracey, Kevin J

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Unraveling Multiple MHC Gene Associations with Systemic Lupus Erythematosus: Model Choice Indicates a Role for HLA Alleles and Non-HLA Genes in Europeans von MORRIS, David L, TAYLOR, Kimberly E, PONS-ESTEL, Bernardo A, GREGERSEN, Peter K, HARLEY, John B, HAUSER, Stephen L, HOM, Geoffrey, LANGEFELD, Carl D, NOBLE, Janelle A, RIOUX, John D, SELDIN, Michael F, CRISWELL, Lindsey A, FERNANDO, Michelle M. A, VYSE, Timothy J, NITITHAM, Joanne, ALARCON-RIQUELME, Marta E, BARCELLOS, Lisa F, BEHRENS, Timothy W, COTSAPAS, Chris, GAFFNEY, Patrick M, GRAHAM, Robert R

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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A von Brown, Anna-Leigh, Wilkins, Oscar G., Keuss, Matthew J., Hill, Sarah E., Zanovello, Matteo, Lee, Weaverly Colleen, Bampton, Alexander, Lee, Flora C. Y., Masino, Laura, Qi, Yue A., Bryce-Smith, Sam, Gatt, Ariana, Hallegger, Martina, Fagegaltier, Delphine, Phatnani, Hemali, Newcombe, Jia, Gustavsson, Emil K., Seddighi, Sahba, Reyes, Joel F., Coon, Steven L., Ramos, Daniel, Schiavo, Giampietro, Fisher, Elizabeth M. C., Raj, Towfique, Secrier, Maria, Lashley, Tammaryn, Ule, Jernej, Buratti, Emanuele, Humphrey, Jack, Ward, Michael E., Fratta, Pietro

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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes von Robertson, Catherine C., Inshaw, Jamie R. J., Onengut-Gumuscu, Suna, Chen, Wei-Min, Santa Cruz, David Flores, Yang, Hanzhi, Cutler, Antony J., Crouch, Daniel J. M., Farber, Emily, Bridges, S. Louis, Edberg, Jeffrey C., Kimberly, Robert P., Buckner, Jane H., Deloukas, Panos, Divers, Jasmin, Dabelea, Dana, Lawrence, Jean M., Marcovina, Santica, Shah, Amy S., Greenbaum, Carla J., Atkinson, Mark A., Gregersen, Peter K., Oksenberg, Jorge R., Pociot, Flemming, Rewers, Marian J., Steck, Andrea K., Dunger, David B., Wicker, Linda S., Concannon, Patrick, Todd, John A., Rich, Stephen S.

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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis von Stahl, Eli A, Wegmann, Daniel, Trynka, Gosia, Gutierrez-Achury, Javier, Do, Ron, Voight, Benjamin F, Kraft, Peter, Chen, Robert, Kallberg, Henrik J, Kurreeman, Fina A S, Kathiresan, Sekar, Wijmenga, Cisca, Gregersen, Peter K, Alfredsson, Lars, Siminovitch, Katherine A, Worthington, Jane, de Bakker, Paul I W, Raychaudhuri, Soumya, Plenge, Robert M

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Microbiota‐dependent metabolite trimethylamine‐N‐oxide is associated with disease severity and survival of patients with chronic heart failure von Trøseid, M., Ueland, T., Hov, J. R., Svardal, A., Gregersen, I., Dahl, C. P., Aakhus, S., Gude, E., Bjørndal, B., Halvorsen, B., Karlsen, T. H., Aukrust, P., Gullestad, L., Berge, R. K., Yndestad, A.

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Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases von Acosta-Herrera, M, Kerick, M, Gonzalez-Serna, D, Wijmenga, C, Franke, A, Gregersen, PK, Padyukov, L, Worthington, J, Vyse, TJ, Alarcon-Riquelme, ME, Mayes, MD, Martin, J, Miller, FW, Chen, W, O'Hanlon, TP, Cooper, RG, Vencovsky, J, Rider, LG, Danko, K, Wedderburn, LR, Lundberg, IE, Pachman, LM, Reed, AM, Ytterberg, SR, Selva-O'Callaghan, A, Radstake, TR, Isenberg, DA, Chinoy, H, Ollier, WER, Scheet, P, Peng, B, Lee, A, Lamb, JA, Amos, CI, Denton, C, Hilton-Jones, D, Plotz, PH, Varsani, H, Radstake, TRDJ, Gorlova, O, Rueda, B, Martin, JE, Alizadeh, BZ, Palomino-Morales, R, Coenen, MJ, Vonk, MC, Voskuyl, AE, Scheurwegh, AJ, Broen, JC, van Riel, PLCM, van 't Slot, R, Italiaander, A, Ophoff, RA, Riemekasten, G, Hunzelmann, N, Simeon, CP, Ortego-Centeno, N, Gonzalez-Gay, MA, Gonzalez-Escribano, MF, Airo, P, van Laar, J, Herrick, A, Hesselstrand, R, Smith, V, de Keyser, F, Houssiau, F, Chee, MM, Madhok, R, Shiels, P, Westhovens, R, Kreuter, A, Kiener, H, de Baere, E, Witte, T, Klareskog, L, Beretta, L, Scorza, R, Lie, BA, Hoffman-Vold, AM, Carreira, P, Varga, J, Hinchcliff, M, Lee, AT, Ying, J, Han, Y, Weng, SF, Wigley, FM, Hummers, L, Nelson, JL, Agarwal, SK, Assassi, S, Gourh, P, Tan, FK, Koeleman, BPC, Arnett, FC

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MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus von Deng, Yun, Zhao, Jian, Sakurai, Daisuke, Kaufman, Kenneth M, Edberg, Jeffrey C, Kimberly, Robert P, Kamen, Diane L, Gilkeson, Gary S, Jacob, Chaim O, Scofield, R Hal, Langefeld, Carl D, Kelly, Jennifer A, Ramsey-Goldman, Rosalind, Petri, Michelle A, Reveille, John D, Vilá, Luis M, Alarcón, Graciela S, Vyse, Timothy J, Pons-Estel, Bernardo A, Freedman, Barry I, Gaffney, Patrick M, Sivils, Kathy Moser, James, Judith A, Gregersen, Peter K, Anaya, Juan-Manuel, Niewold, Timothy B, Merrill, Joan T, Criswell, Lindsey A, Stevens, Anne M, Boackle, Susan A, Cantor, Rita M, Chen, Weiling, Grossman, Jeniffer M, Hahn, Bevra H, Harley, John B, Alarcόn-Riquelme, Marta E, Brown, Elizabeth E, Tsao, Betty P

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Notch signalling drives synovial fibroblast identity and arthritis pathology von Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L., Gao, Anqi, Watts, Gerald F. M., Major, Triin, Croft, Adam P., Watts, Jordan, Blazar, Philip E., Lange, Jeffrey K., Thornhill, Thomas S., Filer, Andrew, Raza, Karim, Donlin, Laura T., Siebel, Christian W., Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.

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High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis von Eyre, Steve, Bowes, John, Diogo, Dorothée, Lee, Annette, Barton, Anne, Martin, Paul, Zhernakova, Alexandra, Stahl, Eli, Viatte, Sebastien, McAllister, Kate, Amos, Christopher I, Padyukov, Leonid, Toes, Rene E M, Huizinga, Tom W J, Wijmenga, Cisca, Trynka, Gosia, Franke, Lude, Westra, Harm-Jan, Alfredsson, Lars, Hu, Xinli, Sandor, Cynthia, de Bakker, Paul I W, Davila, Sonia, Khor, Chiea Chuen, Heng, Khai Koon, Andrews, Robert, Edkins, Sarah, Hunt, Sarah E, Langford, Cordelia, Symmons, Deborah, Concannon, Pat, Onengut-Gumuscu, Suna, Rich, Stephen S, Deloukas, Panos, Gonzalez-Gay, Miguel A, Rodriguez-Rodriguez, Luis, Ärlsetig, Lisbeth, Martin, Javier, Rantapää-Dahlqvist, Solbritt, Plenge, Robert M, Raychaudhuri, Soumya, Klareskog, Lars, Gregersen, Peter K, Worthington, Jane

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A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB115:01 von Cree, Bruce A C, Rioux, John D, McCauley, Jacob L, Gourraud, Pierre-Antoine F D, Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J, Gregersen, Peter K, Mirel, Daniel, Hafler, David A, Haines, Jonathan L, Pericak-Vance, Margaret A, Compston, Alastair, Sawcer, Stephen J, Oksenberg, Jorge R, Hauser, Stephen L

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