MM/GBSA Binding Energy Prediction on the PDBbind Data Set: Successes, Failures, and Directions for Further Improvement von Greenidge, Paulette A, Kramer, Christian, Mozziconacci, Jean-Christophe, Wolf, Romain M

Volltext

How to Computationally Stack the Deck for Hit-to-Lead Generation: In Silico Molecular Interaction Energy Profiling for de Novo siRNA Guide Strand Surrogate Selection von Greenidge, Paulette A, Blommers, Marcel J. J, Priestle, John P, Hunziker, Jürg

Volltext

Boosting Pose Ranking Performance via Rescoring with MM-GBSA von Greenidge, Paulette A., Lewis, Richard A., Ertl, Peter

Volltext

Introducing the Consensus Modeling Concept in Genetic Algorithms:  Application to Interpretable Discriminant Analysis von Ganguly, Milan, Brown, Nathan, Schuffenhauer, Ansgar, Ertl, Peter, Gillet, Valerie J, Greenidge, Paulette A

Volltext

Pseudoreceptor Modeling: The Construction of Three-Dimensional Receptor Surrogates von Vedani, Angelo, Zbinden, Peter, Snyder, James P, Greenidge, Paulette A

Volltext

Pharmacophores Incorporating Numerous Excluded Volumes Defined by X-ray Crystallographic Structure in Three-Dimensional Database Searching:  Application to the Thyroid Hormone Rece... von Greenidge, Paulette A, Carlsson, Bo, Bladh, Lars-Göran, Gillner, Mikael

Volltext

Generation of Ligand Conformations in Continuum Solvent Consistent with Protein Active Site Topology:  Application to Thrombin von Greenidge, Paulette A, Mérette, Sandrine A. M, Beck, Richard, Dodson, Guy, Goodwin, Christopher A, Scully, Michael F, Spencer, John, Weiser, Jörg, Deadman, John J

Volltext

DNA minor groove recognition properties of pentamidine and its analogs: a molecular modeling study von GREENIDGE, P. A, JENKINS, T. C, NEIDLE, S

Volltext

Factors involved in guanine/cytosine (G/C) selectivity of DNA-binding drugs: a molecular modelling study of ligand interactions with a tyrT DNA sequence von Greenidge, Paulette A., Laughton, Charles A., Jenkins, Terence C., Neidle, Stephen

Volltext

A pseudoreceptor modelling study of the varicella-zoster virus and human thymidine kinase binding sites von Greenidge, P A, Merz, A, Folkers, G

Volltext

The modelling of β2-adrenergic receptors von Greenidge, Paulette A.

Volltext

Serine protease inhibitors compromising a hydrogen-bond acceptor von DEADMAN JOHN J, KAKKAR VIJAY VIR, GREENIDGE PAULETTE A, SCULLY MICHAEL F, HOLLAND RICHARD JONES, GOODWIN CHRISTOPHER A, SPENCER JOHN

Volltext bestellen

Evaluation of machine-learning methods for ligand-based virtual screening von Chen, Beining, Harrison, Robert F, Papadatos, George, Willett, Peter, Wood, David J, Lewell, Xiao Qing, Greenidge, Paulette, Stiefl, Nikolaus

Volltext

Discovery of novel indolinone-based, potent, selective and brain penetrant inhibitors of LRRK2 von Troxler, Thomas, Greenidge, Paulette, Zimmermann, Kaspar, Desrayaud, Sandrine, Drückes, Peter, Schweizer, Tatjana, Stauffer, Daniela, Rovelli, Giorgio, Shimshek, Derya R.

Volltext

Valine 571 Functions as a Regional Organizer in Programming the Glucocorticoid Receptor for Differential Binding of Glucocorticoids and Mineralocorticoids von Lind, Ulrika, Greenidge, Paulette, Gustafsson, Jan-Åke, Wright, Anthony P.H., Carlstedt-Duke, Jan

Volltext

Antimalarial Activity:  The Search for Marine-Derived Natural Products with Selective Antimalarial Activity von Wright, Anthony D, König, Gabriele M, Angerhofer, Cindy K, Greenidge, Paulette, Linden, Anthony, Desqueyroux-Faúndez, Ruth

Volltext

Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and binding von Lind, U, Greenidge, P, Gillner, M, Koehler, K F, Wright, A, Carlstedt-Duke, J

Volltext

Organic compounds to treat hepatitis b virus von GREENIDGE PAULETTE, HUESKEN DIETER, PATTERSON ANDREW, GOSSERT ALVAR, HOLDORF MEGHAN, BARYZA JEREMY LEE, WEILER JAN, FERNANDEZ CESAR, PATNAIK ANUP, RONDEAU JEAN-MICHEL RENE, ZHU MEICHENG, HUNZIKER JUERG, BLOMMERS MARCEL, GENO ERIN, NATT FRANCOIS JEANARLES

Volltext bestellen

3'end caps for RNAi agents for use in RNA interference von GREENIDGE PAULETTE, HUESKEN DIETER, PATTERSON ANDREW, GOSSERT ALVAR, BARYZA JEREMY LEE, WEILER JAN, FERNANDEZ CESAR, PATNAIK ANUP, RONDEAU JEAN-MICHEL RENE, ZHU MEICHENG, HUNZIKER JUERG, BLOMMERS MARCEL, GENO ERIN, NATT FRANCOIS JEANARLES

Volltext bestellen

Functional Probing of the Human Glucocorticoid Receptor Steroid-interacting Surface by Site-directed Mutagenesis von Lind, Ulrika, Greenidge, Paulette, Gillner, Mikael, Koehler, Konrad F., Wright, Anthony, Carlstedt-Duke, Jan

Volltext