Kinase inhibitors: the road ahead von Ferguson, Fleur M., Gray, Nathanael S.

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The rise of degrader drugs von Teng, Mingxing, Gray, Nathanael S.

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The Evolving War on Cancer von Haber, Daniel A., Gray, Nathanael S., Baselga, Jose

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Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer von Dutt, Amit, Ramos, Alex H, Hammerman, Peter S, Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S, Meyerson, Matthew

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The ins and outs of selective kinase inhibitor development von Müller, Susanne, Chaikuad, Apirat, Gray, Nathanael S, Knapp, Stefan

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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency von Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf

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Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation von Zhang, Tinghu, Hatcher, John M., Teng, Mingxing, Gray, Nathanael S., Kostic, Milka

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Targeting cancer with small molecule kinase inhibitors von Zhang, Jianming, Yang, Priscilla L., Gray, Nathanael S.

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YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers von Galli, Giorgio G., Carrara, Matteo, Yuan, Wei-Chien, Valdes-Quezada, Christian, Gurung, Basanta, Pepe-Mooney, Brian, Zhang, Tinghu, Geeven, Geert, Gray, Nathanael S., de Laat, Wouter, Calogero, Raffaele A., Camargo, Fernando D.

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Plasticity in binding confers selectivity in ligand-induced protein degradation von Nowak, Radosław P., DeAngelo, Stephen L., Buckley, Dennis, He, Zhixiang, Donovan, Katherine A., An, Jian, Safaee, Nozhat, Jedrychowski, Mark P., Ponthier, Charles M., Ishoey, Mette, Zhang, Tinghu, Mancias, Joseph D., Gray, Nathanael S., Bradner, James E., Fischer, Eric S.

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Small molecule modulators of antioxidant response pathway von Hur, Wooyoung, Gray, Nathanael S

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EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors von Ercan, Dalia, Choi, Hwan Geun, Yun, Cai-Hong, Capelletti, Marzia, Xie, Ting, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A

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YY1 Is a Structural Regulator of Enhancer-Promoter Loops von Weintraub, Abraham S., Li, Charles H., Zamudio, Alicia V., Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Jaenisch, Rudolf, Bradner, James E., Gray, Nathanael S., Young, Richard A.

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Exploration of Type II Binding Mode: A Privileged Approach for Kinase Inhibitor Focused Drug Discovery? von Zhao, Zheng, Wu, Hong, Wang, Li, Liu, Yi, Knapp, Stefan, Liu, Qingsong, Gray, Nathanael S

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Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance von Zhou, Wen, Whiteley, Aaron T., de Oliveira Mann, Carina C., Morehouse, Benjamin R., Nowak, Radosław P., Fischer, Eric S., Gray, Nathanael S., Mekalanos, John J., Kranzusch, Philip J.

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Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15 von Faust, Tyler B., Yoon, Hojong, Nowak, Radosław P., Donovan, Katherine A., Li, Zhengnian, Cai, Quan, Eleuteri, Nicholas A., Zhang, Tinghu, Gray, Nathanael S., Fischer, Eric S.

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Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation von Olson, Calla M, Jiang, Baishan, Erb, Michael A, Liang, Yanke, Doctor, Zainab M, Zhang, Zinan, Zhang, Tinghu, Kwiatkowski, Nicholas, Boukhali, Myriam, Green, Jennifer L, Haas, Wilhelm, Nomanbhoy, Tyzoon, Fischer, Eric S, Young, Richard A, Bradner, James E, Winter, Georg E, Gray, Nathanael S

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CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer von Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Young, Richard A., Gray, Nathanael S., Zhao, Jean J.

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Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules von Nabet, Behnam, Ferguson, Fleur M., Seong, Bo Kyung A., Kuljanin, Miljan, Leggett, Alan L., Mohardt, Mikaela L., Robichaud, Amanda, Conway, Amy S., Buckley, Dennis L., Mancias, Joseph D., Bradner, James E., Stegmaier, Kimberly, Gray, Nathanael S.

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Partitioning of cancer therapeutics in nuclear condensates von Klein, Isaac A, Boija, Ann, Afeyan, Lena K, Hawken, Susana Wilson, Fan, Mengyang, Dall'Agnese, Alessandra, Oksuz, Ozgur, Henninger, Jonathan E, Shrinivas, Krishna, Sabari, Benjamin R, Sagi, Ido, Clark, Victoria E, Platt, Jesse M, Kar, Mrityunjoy, McCall, Patrick M, Zamudio, Alicia V, Manteiga, John C, Coffey, Eliot L, Li, Charles H, Hannett, Nancy M, Guo, Yang Eric, Decker, Tim-Michael, Lee, Tong Ihn, Zhang, Tinghu, Weng, Jing-Ke, Taatjes, Dylan J, Chakraborty, Arup, Sharp, Phillip A, Chang, Young Tae, Hyman, Anthony A, Gray, Nathanael S, Young, Richard A

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