IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes von Becker, Andreas, Eichentopf, Rico, Sedlmeier, Reinhard, Waniek, Alexander, Cynis, Holger, Koch, Birgit, Stephan, Anett, Bäuscher, Christoph, Kohlmann, Stephanie, Hoffmann, Torsten, Kehlen, Astrid, Berg, Sabine, Freyse, Ernst-Joachim, Osmand, Alexander, Plank, Anne-Christine, Roßner, Steffen, von Hörsten, Stephan, Graubner, Sigrid, Demuth, Hans-Ulrich, Schilling, Stephan

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Comparative characterization of all cellulosomal cellulases from Clostridium thermocellum reveals high diversity in endoglucanase product formation essential for complex activity von Leis, Benedikt, Held, Claudia, Bergkemper, Fabian, Dennemarck, Katharina, Steinbauer, Robert, Reiter, Alarich, Mechelke, Matthias, Moerch, Matthias, Graubner, Sigrid, Liebl, Wolfgang, Schwarz, Wolfgang H, Zverlov, Vladimir V

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Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β von Nussbaum, Justin M., Schilling, Stephan, Cynis, Holger, Silva, Antonia, Swanson, Eric, Wangsanut, Tanaporn, Tayler, Kaycie, Wiltgen, Brian, Hatami, Asa, Rönicke, Raik, Reymann, Klaus, Hutter-Paier, Birgit, Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Glabe, Charles G., Demuth, Hans-Ulrich, Bloom, George S.

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Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Ph... von Jawhar, Sadim, Wirths, Oliver, Schilling, Stephan, Graubner, Sigrid, Demuth, Hans-Ulrich, Bayer, Thomas A.

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Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp: identification of the enzymatic core functions and biochemical complex characteri... von Leis, Benedikt, Held, Claudia, Andreeßen, Björn, Liebl, Wolfgang, Graubner, Sigrid, Schulte, Louis-Philipp, Schwarz, Wolfgang H, Zverlov, Vladimir V

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Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation von Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Becker, Andreas, Bäuscher, Christoph, Kohlmann, Stephanie, Sedlmeier, Reinhard, Raber, Kerstin A, Cynis, Holger, Rönicke, Raik, Reymann, Klaus G, Petrasch-Parwez, Elisabeth, Hartlage-Rübsamen, Maike, Waniek, Alexander, Rossner, Steffen, Schilling, Stephan, Osmand, Alexander P, Demuth, Hans-Ulrich, von Hörsten, Stephan

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Glutaminyl Cyclases as Novel Targets for the Treatment of Septic Arthritis von Hellvard, Annelie, Maresz, Katarzyna, Schilling, Stephan, Graubner, Sigrid, Heiser, Ulrich, Jonsson, Roland, Cynis, Holger, Demuth, Hans-Ulrich, Potempa, Jan, Mydel, Piotr

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The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions von Cynis, Holger, Hoffmann, Torsten, Friedrich, Daniel, Kehlen, Astrid, Gans, Kathrin, Kleinschmidt, Martin, Rahfeld, Jens‐Ulrich, Wolf, Raik, Wermann, Michael, Stephan, Anett, Haegele, Monique, Sedlmeier, Reinhard, Graubner, Sigrid, Jagla, Wolfgang, Müller, Anke, Eichentopf, Rico, Heiser, Ulrich, Seifert, Franziska, Quax, Paul H. A., de Vries, Margreet R., Hesse, Isabel, Trautwein, Daniela, Wollert, Ulrich, Berg, Sabine, Freyse, Ernst‐Joachim, Schilling, Stephan, Demuth, Hans‐Ulrich

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Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration von Becker, Andreas, Kohlmann, Stephanie, Alexandru, Anca, Jagla, Wolfgang, Canneva, Fabio, Bäuscher, Christoph, Cynis, Holger, Sedlmeier, Reinhard, Graubner, Sigrid, Schilling, Stephan, Demuth, Hans-Ulrich, von Hörsten, Stephan

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Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development von Schilling, Stephan, Kohlmann, Stephanie, Bäuscher, Christoph, Sedlmeier, Reinhard, Koch, Birgit, Eichentopf, Rico, Becker, Andreas, Cynis, Holger, Hoffmann, Torsten, Berg, Sabine, Freyse, Ernst-Joachim, von Hörsten, Stephan, Rossner, Steffen, Graubner, Sigrid, Demuth, Hans-Ulrich

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Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-[Beta] von Nussbaum, Justin M, Schilling, Stephan, Cynis, Holger, Silva, Antonia, Swanson, Eric, Wangsanut, Tanaporn, Tayler, Kaycie, Wiltgen, Brian, Hatami, Asa, Rönicke, Raik, Reymann, Klaus, Hutter-Paier, Birgit, Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Glabe, Charles G, Demuth, Hans-Ulrich, Bloom, George S

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Prion-Like Behavior and Tau-dependent Cytotoxicity of Pyroglutamylated β-Amyloid von Nussbaum, Justin M., Schilling, Stephan, Cynis, Holger, Silva, Antonia, Swanson, Eric, Wangsanut, Tanaporn, Tayler, Kaycie, Wiltgen, Brian, Hatami, Asa, Rönicke, Raik, Reymann, Klaus, Hutter-Paier, Birgit, Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Glabe, Charles G., Demuth, Hans-Ulrich, Bloom, George S.

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Glutaminyl Cyclase Knock-out Mice Exhibit Slight Hypothyroidism but No Hypogonadism von Schilling, Stephan, Kohlmann, Stephanie, Bäuscher, Christoph, Sedlmeier, Reinhard, Koch, Birgit, Eichentopf, Rico, Becker, Andreas, Cynis, Holger, Hoffmann, Torsten, Berg, Sabine, Freyse, Ernst-Joachim, von Hörsten, Stephan, Rossner, Steffen, Graubner, Sigrid, Demuth, Hans-Ulrich

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P1‐323: Distinct role of Glutaminyl Cyclases (QCs) in inflammation/neuroinflammation: First results from QC and isoQC knock out mice von Cynis, Holger, Graubner, Sigrid, Alexandru, Anca, Gans, Kathrin, Schilling, Stephan, Demuth, Hans-Ulrich

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P3‐407: Inhibition of Glutaminyl Cyclase: Pharmacology and steps towards clinical development von Demuth, Hans-Ulrich, Cynis, Holger, Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Stephan v. Hoersten, Schilling, Stephan

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Distinct role of Glutaminyl Cyclases (QCs) in inflammation/neuroinflammation: First results from QC and isoQC knock out mice von Cynis, Holger, Graubner, Sigrid, Alexandru, Anca, Gans, Kathrin, Schilling, Stephan, Demuth, Hans-Ulrich

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Inhibition of Glutaminyl Cyclase: Pharmacology and steps towards clinical development von Demuth, Hans-Ulrich, Cynis, Holger, Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Stephan v. Hoersten, Schilling, Stephan

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P4‐015: Behavioral characterization of a new transgenic mouse model of pGlu‐Aβ induced neurotoxicity: Automated, high‐resolution, intra‐home‐cage and ethological‐based phenotyping... von Baeuscher, Christoph, Kohlmann, Stephanie, Graubner, Sigrid, Alexandru, Anca, Jagla, Wolfgang, Schilling, Stephan, Hoersten, Stephan, Demuth, Hans‐Ulrich

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P4‐014: Behavioral phenotyping of a new transgenic mouse model of pGlu‐Aβ induced neurotoxicity: Classical behavioral approach von Kohlmann, Stephanie, Baeuscher, Christoph, Graubner, Sigrid, Alexandru, Anca, Jagla, Wolfgang, Schilling, Stephan, Hörsten, Stephan, Demuth, Hans‐Ulrich

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Behavioral characterization of a new transgenic mouse model of pGlu-Aβ induced neurotoxicity: Automated, high-resolution, intra-home-cage and ethological-based phenotyping von Baeuscher, Christoph, Kohlmann, Stephanie, Graubner, Sigrid, Alexandru, Anca, Jagla, Wolfgang, Schilling, Stephan, von Hoersten, Stephan, Demuth, Hans-Ulrich

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