Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma von Weinhold, Niels, Kirn, Desiree, Seckinger, Anja, Hielscher, Thomas, Granzow, Martin, Bertsch, Uta, Egerer, Gerlinde, Salwender, Hans, Blau, Igor W, Weisel, Katja, Hillengass, Jens, Raab, Marc S, Hose, Dirk, Goldschmidt, Hartmut, Jauch, Anna

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Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control von Hoffmann, S., Schmitteckert, S., Raedecke, K., Rheinert, D., Diebold, S., Roeth, R., Weiss, B., Granzow, M., Niesler, B., Griesbeck, A., Eckstein, V., Zimmermann, W.-H., Just, S., Rappold, G.A.

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Loss of function of PGAP1 as a cause of severe encephalopathy identified by Whole Exome Sequencing: Lessons of the bioinformatics pipeline von Granzow, M., Paramasivam, N., Hinderhofer, K., Fischer, C., Chotewutmontri, S., Kaufmann, L., Evers, C., Kotzaeridou, U., Rohrschneider, K., Schlesner, M., Sturm, M., Pinkert, S., Eils, R., Bartram, C.R., Bauer, P., Moog, U.

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368 INHIBITION OF JANUS-KINASE 2 BLUNTS AT1-RECEPTOR MEDIATED HEPATIC FIBROSIS von Granzow, M, Klein, S, Schierwagen, R, Huss, S, Sauerbruch, T, Heinzen, J

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367 ROLE OF BETA-ARRESTIN-2 IN THE DEVELOPMENT OF HEPATIC FIBROSIS von Granzow, M, Klein, S, Schierwagen, R, Heinzen, J, Huss, S, Sauerbruch, T, Trebicka, J

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375 REDUCTION OF PORTAL PRESSURE BY JAK2 INHIBITION IN CIRRHOSIS WITH PORTAL HYPERTENSION von Klein, S, Granzow, M, Schierwagen, R, Kahrmann, K, Kowallick, B, Laleman, W, Sauerbruch, T, Trebicka, J

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The RIN: an RNA integrity number for assigning integrity values to RNA measurements von Schroeder, Andreas, Mueller, Odilo, Stocker, Susanne, Salowsky, Ruediger, Leiber, Michael, Gassmann, Marcus, Lightfoot, Samar, Menzel, Wolfram, Granzow, Martin, Ragg, Thomas

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374 HSC-DIRECTED RHO-KINASE INHIBITION IS AN EFFECTIVE AND SAVE APPROACH FOR TREATMENT OF PORTAL HYPERTENSION von Klein, S, Granzow, M, Schierwagen, R, Kilic, S, Heidari, I, Huss, S, Van Beuge, M, Sauerbruch, T, Poelstra, K, Trebicka, J

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376 STATINS INDUCE SENESCENCE OF ACTIVATED HSC BY INHIBITION OF THE HEDGEHOG PATHWAY von Klein, S, Granzow, M, Schierwagen, R, Van der Ven, P, Raskopf, E, Pieper-Fürst, U, Fürst, D, Lammert, F, Choi, S, Diehl, A.M, Shah, V, Sauerbruch, T, Trebicka, J

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193 DECREASE OF PORTAL PRESSURE VIA TIPS CORRECTS CONTRACTILE MECHANISMS IN GASTRIC MUCOSA OF HUMAN CIRRHOSIS von Trebicka, J, Krag, A, Wix, C, Granzow, M, Klein, S, Appenrodt, B, Saller, S, Heller, J, Sauerbruch, T

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1041 HSC SPECIFIC INHIBITION OF RHO-KINASE REDUCES PORTAL PRESSURE WITHOUT SYSTEMIC EFFECTS von Klein, S, Granzow, M, Gautsch, S, van Beuge, M.M, Poelstra, K, Sauerbruch, T, Trebicka, J

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542 STATIN TREATMENT DECREASE COLLATERAL FLOW AND PORTAL PRESSURE IN CIRRHOSIS, BUT NOT IN PREHEPATIC PORTAL HYPERTENSION von Trebicka, J, Klein, S, Granzow, M, Ranabhat, G, Hennenberg, M, Raskopf, E, Gautsch, S, Schmitz, V, Sauerbruch, T

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543 INCREASED ENOS- AND DECREASED RHO-KINASE ACTIVITY ARE ASSOCIATED WITH PORTAL-HYPERTENSIVE GASTROPATHY IN HUMANEN CIRRHOSIS von Trebicka, J, Granzow, M, Klein, S, Wix, C, Hennenberg, M, Appenrodt, B, Heller, J, Sauerbruch, T

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miRNA-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in Irritable Bowel Syndrome (IBS) von Schmitteckert, S, Wohlfarth, C, Hartle, JD, Houghton, L, Dweep, H, Fortea, M, Ghazaleh, A, Braun, A, Mederer, T, Sarina, P, Becker, PP, Fischer, C, Granzow, M, Monnikes, H, Mayer, EA, Sayuk, G, Boeckxstaens, G, Wouters, M, Simren, M, Lindberg, G, Ohlsson, B, Schmidt, PT, Dlugosz, A, Agreus, L, Andreasson, A, D'Amato, M, Burwinkel, B, Lorenzo, J, Roth, R, Lastischka, F, Vicario, M, Metzger, M, Santos, J, Rappold, GA, Martinez, C, Niesler, B

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From Latent Disseminated Cells to Overt Metastasis: Genetic Analysis of Systemic Breast Cancer Progression von Schmidt-Kittler, Oleg, Ragg, Thomas, Daskalakis, Angela, Granzow, Martin, Ahr, Andre, Thomas J. F. Blankenstein, Kaufmann, Manfred, Diebold, Joachim, Arnholdt, Hans, Müller, Peter, Bischoff, Joachim, Harich, Detlev, Schlimok, Günter, Riethmüller, Gert, Eils, Roland, Klein, Christoph A.

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Big Data in Medicine Is Driving Big Changes von Martin-Sanchez, F., Verspoor, K.

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miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome von Wohlfarth, Carolin, Schmitteckert, Stefanie, Härtle, Janina D., Houghton, Lesley A., Dweep, Harsh, Fortea, Marina, Assadi, Ghazaleh, Braun, Alexander, Mederer, Tanja, Pöhner, Sarina, Becker, Philip P., Fischer, Christine, Granzow, Martin, Mönnikes, Hubert, Mayer, Emeran A., Sayuk, Gregory, Boeckxstaens, Guy, Wouters, Mira M., Simrén, Magnus, Lindberg, Greger, Ohlsson, Bodil, Schmidt, Peter Thelin, Dlugosz, Aldona, Agreus, Lars, Andreasson, Anna, D’Amato, Mauro, Burwinkel, Barbara, Bermejo, Justo Lorenzo, Röth, Ralph, Lasitschka, Felix, Vicario, Maria, Metzger, Marco, Santos, Javier, Rappold, Gudrun A., Martinez, Cristina, Niesler, Beate

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3p25.3 microdeletion of GABA transporters SLC6A1 and SLC6A11 results in intellectual disability, epilepsy and stereotypic behavior von Dikow, Nicola, Maas, Bianca, Karch, Stephanie, Granzow, Martin, Janssen, Johannes W.G., Jauch, Anna, Hinderhofer, Katrin, Sutter, Christian, Schubert-Bast, Susanne, Anderlid, Britt Marie, Dallapiccola, Bruno, Van der Aa, Nathalie, Moog, Ute

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Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2 von Joos, Stefan, Granzow, Martin, Holtgreve‐Grez, Heidi, Siebert, Reiner, Harder, Lana, Martín‐Subero, José I., Wolf, Jürgen, Adamowicz, Martyna, Barth, Thomas F.E., Lichter, Peter, Jauch, Anna

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Informatics United Exemplary Studies Combining Medical Informatics, Neuroinformatics and Bioinformatics von WIGMER, J, SCHUBERT, F, GRANZOW, M, RAGG, T, FIERES, J, MOTTES, J, EILS, R

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