Mechanisms of action of ribavirin against distinct viruses von Graci, Jason D., Cameron, Craig E.

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Small molecule splicing modifiers with systemic HTT-lowering activity von Bhattacharyya, Anuradha, Trotta, Christopher R., Narasimhan, Jana, Wiedinger, Kari J., Li, Wencheng, Effenberger, Kerstin A., Woll, Matthew G., Jani, Minakshi B., Risher, Nicole, Yeh, Shirley, Cheng, Yaofeng, Sydorenko, Nadiya, Moon, Young-Choon, Karp, Gary M., Weetall, Marla, Dakka, Amal, Gabbeta, Vijayalakshmi, Naryshkin, Nikolai A., Graci, Jason D., Tripodi, Thomas, Southwell, Amber, Hayden, Michael, Colacino, Joseph M., Peltz, Stuart W.

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The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines von Luban, Jeremy, Sattler, Rachel A., Mühlberger, Elke, Graci, Jason D., Cao, Liangxian, Weetall, Marla, Trotta, Christopher, Colacino, Joseph M., Bavari, Sina, Strambio-De-Castillia, Caterina, Suder, Ellen L., Wang, Yetao, Soloveva, Veronica, Cintron-Lue, Katherine, Naryshkin, Nikolai A., Pykett, Mark, Welch, Ellen M., O’Keefe, Kylie, Kong, Ronald, Goodwin, Elizabeth, Jacobson, Allan, Paessler, Slobodan, Peltz, Stuart W.

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RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence von Korboukh, Victoria K., Lee, Cheri A., Acevedo, Ashley, Vignuzzi, Marco, Xiao, Yinghong, Arnold, Jamie J., Hemperly, Stephen, Graci, Jason D., August, Avery, Andino, Raul, Cameron, Craig E.

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Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis von GRACI, Jason D, GNÄDIG, Nina F, GALARRAGA, Jessica E, CASTRO, Christian, VIGNUZZI, Marco, CAMERON, Craig E

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Emvododstat, a Potent Dihydroorotate Dehydrogenase Inhibitor, Is Effective in Preclinical Models of Acute Myeloid Leukemia von Branstrom, Arthur, Cao, Liangxian, Furia, Bansri, Trotta, Christopher, Santaguida, Marianne, Graci, Jason D, Colacino, Joseph M, Ray, Balmiki, Li, Wencheng, Sheedy, Josephine, Mollin, Anna, Yeh, Shirley, Kong, Ronald, Sheridan, Richard, Baird, John D, O'Keefe, Kylie, Spiegel, Robert, Goodwin, Elizabeth, Keating, Suzanne, Weetall, Marla

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Identification of benzazole compounds that induce HIV-1 transcription von Graci, Jason D, Michaels, Daniel, Chen, Guangming, Schiralli Lester, Gillian M, Nodder, Sarah, Weetall, Marla, Karp, Gary M, Gu, Zhengxian, Colacino, Joseph M, Henderson, Andrew J

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Quasispecies, Error Catastrophe, and the Antiviral Activity of Ribavirin von Graci, Jason D., Cameron, Craig E.

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Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein von Gu, Zhengxian, Graci, Jason D, Lahser, Frederick C, Breslin, Jamie J, Jung, Stephen P, Crona, James H, McMonagle, Patricia, Xia, Ellen, Liu, Shaotang, Karp, Gary, Zhu, Jin, Huang, Song, Nomeir, Amin, Weetall, Marla, Almstead, Neil G, Peltz, Stuart W, Tong, Xiao, Ralston, Robert, Colacino, Joseph M

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Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties von Cao, Liangxian, Weetall, Marla, Trotta, Christopher, Cintron, Katherine, Ma, Jiyuan, Kim, Min Jung, Furia, Bansri, Romfo, Charles, Graci, Jason D, Li, Wencheng, Du, Joshua, Sheedy, Josephine, Hedrick, Jean, Risher, Nicole, Yeh, Shirley, Qi, Hongyan, Arasu, Tamil, Hwang, Seongwoo, Lennox, William, Kong, Ronald, Petruska, Janet, Moon, Young-Choon, Babiak, John, Davis, Thomas W, Jacobson, Allan, Almstead, Neil G, Branstrom, Art, Colacino, Joseph M, Peltz, Stuart W

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Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues von GRACI, Jason D, TOO, Kathleen, BROWN, Daniel M, CAMERON, Craig E, SMIDANSKY, Eric D, EDATHIL, Jocelyn P, BARR, Eric W, HARKI, Daniel A, GALARRAGA, Jessica E, BOLLINGER, J. Martin, PETERSON, Blake R, LOAKES, David

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Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue von GRACI, Jason D, HARKI, Daniel A, LOAKES, David, CAMERON, Craig E, KORNEEVA, Victoria S, EDATHIL, Jocelyn P, TOO, Kathleen, FRANCO, David, SMIDANSKY, Eric D, PAUL, Aniko V, PETERSON, Blake R, BROWN, Daniel M

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Macrolide drug interactions: an update von Pai, MP, Graci, DM, Amsden, GW

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PTC725, an NS4B-Targeting Compound, Inhibits a Hepatitis C Virus Genotype 3 Replicon, as Predicted by Genome Sequence Analysis and Determined Experimentally von Graci, Jason D, Jung, Stephen P, Pichardo, John, Lahser, Frederick, Tong, Xiao, Gu, Zhengxian, Colacino, Joseph M

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Synthesis and Antiviral Evaluation of a Mutagenic and Non-Hydrogen Bonding Ribonucleoside Analogue:  1-β-d-Ribofuranosyl-3-nitropyrrole von Harki, Daniel A, Graci, Jason D, Korneeva, Victoria S, Ghosh, Saikat Kumar B, Hong, Zhi, Cameron, Craig E, Peterson, Blake R

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Higher PV Module Efficiency by a Novel CBS Bypass von Acciari, G, Graci, D, La Scala, A

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High-throughput Screening Uncovers a Compound That Activates Latent HIV-1 and Acts Cooperatively with a Histone Deacetylase (HDAC) Inhibitor von Micheva-Viteva, Sofiya, Kobayashi, Yoshifumi, Edelstein, Leonard C., Pacchia, Annmarie L., Lee, Hui-Ling Rose, Graci, Jason D., Breslin, Jamie, Phelan, Bradley D., Miller, Leia K., Colacino, Joseph M., Gu, Zhengxian, Ron, Yacov, Peltz, Stuart W., Dougherty, Joseph P.

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Challenges for the Development of Ribonucleoside Analogues as Inducers of Error Catastrophe von Graci, Jason D, Cameron, Craig E

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Effects of Introduction of Hydrophobic Group on Ribavirin Base on Mutation Induction and Anti-RNA Viral Activity von Moriyama, Kei, Suzuki, Tetsuya, Negishi, Kazuo, Graci, Jason D, Thompson, Corinne N, Cameron, Craig E, Watanabe, Masahiko

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Synthesis and Antiviral Activity of 5-Substituted Cytidine Analogues:  Identification of a Potent Inhibitor of Viral RNA-Dependent RNA Polymerases von Harki, Daniel A, Graci, Jason D, Galarraga, Jessica E, Chain, William J, Cameron, Craig E, Peterson, Blake R

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