Rhodium-carbenoid-mediated intermolecular O–H insertion reactions: a dramatic additive effect. Application in the synthesis of an ascomycin derivative von Nelson, Todd D, Song, Zhiguo Jake, Thompson, Andrew S, Zhao, Mangzhu, DeMarco, Anthony, Reamer, Robert A, Huntington, Martha F, Grabowski, Edward J.J, Reider, Paul J

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Enantiopure drug synthesis: From methyldopa to imipenem to efavirenz von Grabowski, Edward J.J.

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A novel chromium trioxide catalyzed oxidation of primary alcohols to the carboxylic acids von Zhao, Mangzhu, Li, Jing, Song, Zhiguo, Desmond, Richard, Tschaen, David M., Grabowski, Edward J.J., Reider, Paul J.

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Scalable, efficient process for the synthesis of ( R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion comple... von Hansen, Karl B., Chilenski, Jennifer R., Desmond, Richard, Devine, Paul N., Grabowski, Edward J.J., Heid, Richard, Kubryk, Michele, Mathre, David J., Varsolona, Richard

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A new general method for preparation of N-methoxy- N-methylamides. Application in direct conversion of an ester to a ketone von Williams, J.Michael, Jobson, Ronald B., Yasuda, Nobuyoshi, Marchesini, George, Dolling, Ulf-H., Grabowski, Edward J.J.

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Highly Efficient Asymmetric Synthesis of Sitagliptin von Hansen, Karl B, Hsiao, Yi, Xu, Feng, Rivera, Nelo, Clausen, Andrew, Kubryk, Michele, Krska, Shane, Rosner, Thorsten, Simmons, Bryon, Balsells, Jaume, Ikemoto, Nori, Sun, Yongkui, Spindler, Felix, Malan, Christophe, Grabowski, Edward J. J, Armstrong, Joseph D

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Practical synthesis of a highly functionalized thiazole ketone von Frey, Lisa F, Marcantonio, Karen M, Chen, Cheng-yi, Wallace, Debra J, Murry, Jerry A, Tan, Lushi, Chen, Weirong, Dolling, Ulf H, Grabowski, Edward J.J

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Highly Efficient Synthesis of β-Amino Acid Derivatives via Asymmetric Hydrogenation of Unprotected Enamines von Hsiao, Yi, Rivera, Nelo R, Rosner, Thorsten, Krska, Shane W, Njolito, Eugenia, Wang, Fang, Sun, Yongkui, Armstrong, Joseph D, Grabowski, Edward J. J, Tillyer, Richard D, Spindler, Felix, Malan, Christophe

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Highly Regioselective Synthesis of 1-Aryl-3,4,5-Substituted Pyrazoles von Gosselin, Francis, O’Shea, Paul D., Webster, Robert A., Reamer, Robert A., Tillyer, Richard D., Grabowski, Edward J.

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Synthesis of Substituted Imidazoles via Organocatalysis von Frantz, Doug E, Morency, Louis, Soheili, Arash, Murry, Jerry A, Grabowski, Edward J. J, Tillyer, Richard D

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Practical enantioselective synthesis of a COX-2 specific inhibitor von Tan, Lushi, Chen, Cheng-yi, Chen, Weirong, Frey, Lisa, King, Anthony O, Tillyer, Richard D, Xu, Feng, Zhao, Dalian, Grabowski, Edward J.J, Reider, Paul J, O'Shea, Paul, Dagneau, Philippe, Wang, Xin

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Asymmetric synthesis of cis -aminochromanol von Hansen, Karl B, Rabbat, Philippe, Springfield, Shawn A, Devine, Paul N, Grabowski, Edward J.J, Reider, Paul J

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Radical alkylation of N-alkyl 1,2,4-triazoles von Hansen, Karl B, Springfield, Shawn A, Desmond, Richard, Devine, Paul N, Grabowski, Edward J.J, Reider, Paul J

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Practical chemoenzymatic synthesis of a 3-pyridylethanolamino β3 adrenergic receptor agonist von Chung, John Y.L, Ho, Guo-Jie, Chartrain, Michel, Roberge, Chris, Zhao, Dalian, Leazer, John, Farr, Roger, Robbins, Michael, Emerson, Kateeta, Mathre, David J, McNamara, James M, Hughes, David L, Grabowski, Edward J.J, Reider, Paul J

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Practical routes toward the synthesis of 2-halo- and 2-alkylamino-4-pyridinecarboxaldehydes von Frey, Lisa F, Marcantonio, Karen, Frantz, Doug E, Murry, Jerry A, Tillyer, Richard D, Grabowski, Edward J.J, Reider, Paul J

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First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin von Hansen, Karl B, Balsells, Jaume, Dreher, Spencer, Hsiao, Yi, Kubryk, Michele, Palucki, Michael, Rivera, Nelo, Steinhuebel, Dietrich, Armstrong, Joseph D, Askin, David, Grabowski, Edward J. J

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A Novel, Highly Enantioselective Ketone Alkynylation Reaction Mediated by Chiral Zinc Aminoalkoxides von Tan, Lushi, Chen, Cheng-yi, Tillyer, Richard D., Grabowski, Edward J. J., Reider, Paul J.

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Stereoselective Formation of Carbon−Carbon Bonds via SN2-Displacement:  Synthesis of Substituted Cycloalkyl[b]indoles von Hillier, Michael C, Marcoux, Jean-François, Zhao, Dalian, Grabowski, Edward J. J, McKeown, Arlene E, Tillyer, Richard D

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Mechanistic Evidence for an α-Oxoketene Pathway in the Formation of β-Ketoamides/Esters via Meldrum's Acid Adducts von Xu, Feng, Armstrong, Joseph D, Zhou, George X, Simmons, Bryon, Hughes, David, Ge, Zhihong, Grabowski, Edward J. J

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Asymmetric Synthesis of a Prostaglandin D2 Receptor Antagonist von Campos, Kevin R, Journet, Michel, Lee, Sandra, Grabowski, Edward J. J, Tillyer, Richard D

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