Biology of IL‐38 and its role in disease von Veerdonk, Frank L., Graaf, Dennis M., Joosten, Leo AB, Dinarello, Charles A.

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IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease von Højen, Jesper Falkesgaard, Kristensen, Marie Louise Vindvad, McKee, Amy S., Wade, Megan Taylor, Azam, Tania, Lunding, Lars P., de Graaf, Dennis M., Swartzwelter, Benjamin J., Wegmann, Michael, Tolstrup, Martin, Beckman, Karsten, Fujita, Mayumi, Fischer, Stephan, Dinarello, Charles A.

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IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling von Graaf, Dennis M., Teufel, Lisa U., Veerdonk, Frank L., Joosten, Leo A. B., Netea, Mihai G., Dinarello, Charles A., Arts, Rob J. W.

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NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis von Marchetti, Carlo, Swartzwelter, Benjamin, Koenders, Marije I, Azam, Tania, Tengesdal, Isak W, Powers, Nick, de Graaf, Dennis M, Dinarello, Charles A, Joosten, Leo A B

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Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects von Graaf, Dennis M., Jaeger, Martin, Munckhof, Inge C. L., Horst, Rob, Schraa, Kiki, Zwaag, Jelle, Kox, Matthijs, Fujita, Mayumi, Yamauchi, Takeshi, Mercurio, Laura, Madonna, Stefania, Rutten, Joost H.W., Graaf, Jacqueline, Riksen, Niels P., Veerdonk, Frank L., Netea, Mihai G., Joosten, Leo A.B., Dinarello, Charles A.

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Circulating interleukin-38 concentrations in healthy adults von Teufel, Lisa U, de Graaf, Dennis M, Netea, Mihai G, Dinarello, Charles A, Joosten, Leo A B, Arts, Rob J W

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Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls von Gaal, Orsolya I, Leask, Megan, Nica, Valentin, Cabău, Georgiana, Badii, Medeea, Hotea, Ioana, de Graaf, Dennis M, Zhang, Zhenhua, Li, Yang, Pamfil, Cristina, Rednic, Simona, Merriman, Tony R, Crișan, Tania O, Joosten, Leo A B

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IL-38 Gene Deletion Worsens Murine Colitis von de Graaf, Dennis M, Wang, Ruth X, Amo-Aparicio, Jesús, Lee, J Scott, Dowdell, Alexander S, Tengesdal, Isak W, Marchetti, Carlo, Colgan, Sean P, Joosten, Leo A B, Dinarello, Charles A

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Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients von Graaf, Dennis M., Teufel, Lisa U., Nooijer, Aline H., Gammeren, Adriaan J., Ermens, Antonius A. M., Gaál, Ildikó O., Crișan, Tania O., Veerdonk, Frank L., Netea, Mihai G., Dinarello, Charles A., Joosten, Leo A. B., Arts, Rob J. W.

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Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion von Tengesdal, Isak W., Menon, Dinoop R., Osborne, Douglas G., Neff, Charles P., Powers, Nicholas E., Gamboni, Fabia, Mauro, Adolfo G., D’Alessandro, Angelo, Stefanoni, Davide, Henen, Morkos A., Mills, Taylor S., DeGraaf, Dennis M., Azam, Tania, Vogeli, Beat, Palmer, Brent E., Pietras, Eric M., DeGregori, James, Tan, Aik-Choon, Joosten, Leo A. B., Fujita, Mayumi, Dinarello, Charles A., Marchetti, Carlo

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Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 von The, Erlinda, de Graaf, Dennis M, Zhai, Yufeng, Yao, Qingzhou, Ao, Lihua, Fullerton, David A, Dinarello, Charles A, Meng, Xianzhong

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Interleukin-38 in Health and Disease von de Graaf, Dennis M., Teufel, Lisa U., Joosten, Leo A.B., Dinarello, Charles A.

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PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis von Powers, Nicholas E., Swartzwelter, Benjamin, Marchetti, Carlo, de Graaf, Dennis M., Lerchner, Alexandra, Schlapschy, Martin, Datar, Rajiv, Binder, Uli, Edwards, Carl K., Skerra, Arne, Dinarello, Charles A.

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IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion von Dinarello, Alberto, May, Makenna, Amo-Aparicio, Jesus, Azam, Tania, Gaballa, Joseph M, Marchetti, Carlo, Tesoriere, Annachiara, Ghirardo, Rachele, Redzic, Jasmina S, Webber, 3rd, William S, Atif, Shaikh M, Li, Suzhao, Eisenmesser, Elan Z, de Graaf, Dennis M, Dinarello, Charles A

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International nomenclature guidelines for the IL-1 family of cytokines and receptors von Gaballa, Joseph M., Højen, Jesper Falkesgaard, De Graaf, Dennis M., Amo-Aparicio, Jesus, Marchetti, Carlo, Cavalli, Giulio, Dinarello, Alberto, Li, Suzhao, Corbisiero, Michaele Francesco, Tengesdal, Isak W., Redzic, Jasmina S., Azam, Tania, Webber, William S., Pankratz, Karl A., May, Makenna J., Cominelli, Fabio, Eisenmesser, Elan Z., Kim, Soohyun, Dinarello, Charles A., Boraschi, Diana

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A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling von Li, Suzhao, Jiang, Liqiong, Beckmann, Karsten, Højen, Jesper Falkesgaard, Pessara, Ulrich, Powers, Nicholas E., de Graaf, Dennis M., Azam, Tania, Lindenberger, Jared, Eisenmesser, Elan Z., Fischer, Stephan, Dinarello, Charles A.

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Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease von de Graaf, Dennis M., Maas, Ralph J.A., Smeekens, Sanne P., Eisenmesser, Elan, Redzic, Jasmina S., Helsen, Monique M., Powers, Nicholas E., Li, Suzhao, Kalabokis, Vassili, Gresnigt, Mark S., Joosten, Leo A.B., Dinarello, Charles A., van de Veerdonk, Frank L.

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Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans von Grander, Christoph, Schaefer, Benedikt, Schwärzler, Julian, Grabherr, Felix, de Graaf, Dennis M, Enrich, Barbara, Oberhuber, Georg, Mayr, Lisa, Sangineto, Moris, Jaschke, Nikolai, Adolph, Timon E, Effenberger, Maria, Moschen, Alexander R, Dinarello, Charles A, Zoller, Heinz, Tilg, Herbert

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PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis von Powers, Nicholas E., Swartzwelter, Benjamin, Marchetti, Carlo, de Graaf, Dennis M., Lerchner, Alexandra, Schlapschy, Martin, Datar, Rajiv, Binder, Uli, Edwards, Carl K., Skerra, Arne, Dinarello, Charles A.

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Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration von Sloot, Yvette J. E., Rabold, Katrin, Ulas, Thomas, De Graaf, Dennis M., Heinhuis, Bas, Händler, Kristian, Schultze, Joachim L., Netea, Mihai G., Smit, Johannes W. A., Joosten, Leo A. B., Netea-Maier, Romana T.

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