TNF‐α‐induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways von Makwana, R, Gozzard, N, Spina, D, Page, C

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CDP840. A prototype of a novel class of orally active anti-Inflammatory phosphodiesterase 4 inhibitors von Alexander, R.P., Warrellow, G.J., Eaton, M.A.W., Boyd, E.C., Head, J.C., Porter, J.R., Brown, J.A., Reuberson, J.T., Hutchinson, B., Turner, P., Boyce, B., Barnes, D., Mason, B., Cannell, A., Taylor, R.J., Zomaya, A., Millican, A., Leonard, J., Morphy, R., Wales, M., Perry, M., Allen, R.A., Gozzard, N., Hughes, B., Higgs, G.

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The effect of anti-integrin monoclonal antibodies on antigen-induced pulmonary inflammation in allergic rabbits von Gascoigne, M.H, Holland, K, Page, C.P, Shock, A, Robinson, M, Foulkes, R, Gozzard, N

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In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes von Berry, L.M., Adams, R., Airey, M., Bracher, M.G., Bourne, T., Carrington, B., Cross, A.S., Davies, G.C.G., Finney, H.M., Foulkes, R., Gozzard, N., Griffin, R.A., Hailu, H., Lamour, S.D., Lawson, A.D., Lightwood, D.J., McKnight, A.J., O'Dowd, V.L., Oxbrow, A.K.F., Popplewell, A.G., Shaw, S., Stephens, P.E., Sweeney, B., Tomlinson, K.L., Uhe, C., Palframan, R.T.

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The inhibition of antigen‐induced eosinophilia and bronchoconstriction by CDP840, a novel stereo‐selective inhibitor of phosphodiesterase type 4 von Hughes, B., Howat, D., Lisle, H., Holbrook, M., James, T., Gozzard, N., Blease, K., Hughes, P., Kingaby, R., Warrellow, G., Alexander, R., Head, J., Boyd, E., Eaton, M., Perry, M., Wales, M., Smith, B., Owens, R., Catterall, C., Lumb, S., Russell, A., Allen, R., Merriman, M., Bloxham, D., Higgs, G.

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The RA-MAP Consortium: a working model for academia–industry collaboration von Cope, Andrew P., Barnes, Michael R., Belson, Alexandra, Binks, Michael, Brockbank, Sarah, Bonachela-Capdevila, Francisco, Carini, Claudio, Fisher, Benjamin A., Goodyear, Carl S., Emery, Paul, Ehrenstein, Michael R., Gozzard, Neil, Harris, Ray, Hollis, Sally, Keidel, Sarah, Levesque, Marc, Lindholm, Catharina, McDermott, Michael F., McInnes, Iain B., Mela, Christopher M., Parker, Gerry, Read, Simon, Pedersen, Ayako Wakatsuki, Ponchel, Frederique, Porter, Duncan, Rao, Ravi, Rowe, Anthony, Schulz-Knappe, Peter, Sleeman, Matthew A., Symmons, Deborah, Taylor, Peter C., Tom, Brian, Tsuji, Wayne, Verbeeck, Denny, Isaacs, John D.

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C32 ASTHMA: PRE-CLINICAL STUDIES: Corticosteroid Insensitivity In A House Dust Mite And Freund's Complete Adjuvant Driven Mouse Model Of Allergic Asthma von Raemdonck, K, Birrell, M A, Gozzard, N, Chung, K F, Belvisi, M G, Adcock, I M

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TNF-[alpha]-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways von Makwana, R, Gozzard, N, Spina, D, Page, C

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C32 CLINICAL ASTHMA II: Transcriptomics Analysis Identifies The Persistent Activation Of Peripheral Airways In Glucocorticosteroid-Treated Severe Asthmatics von Singhania, A, Rupani, H, Jayasekera, N, Lumb, S, Hales, P, Gozzard, N, Davies, D E, Woelk, C H, Howarth, P H

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Inhibition of bronchospasm and ozone‐induced airway hyperresponsiveness in the guinea‐pig by CDP840, a novel phosphodiesterase type 4 inhibitor von Holbrook, Mark, Gozzard, Neil, James, Tina, Higgs, Gerry, Hughes, Bernadette

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Capsaicin pre-treatment prevents the development of antigen-induced airway hyperresponsiveness in neonatally immunised rabbits von Herd, Caroline M., Gozzard, Neil, Page, Clive P.

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Effect of the glucocorticosteroid budesonide and a novel phosphodiesterase type 4 inhibitor CDP840 on antigen‐induced airway responses in neonatally immunised rabbits von Gozzard, N., El‐Hashim, A., Herd, C.M., Blake, S.M., Holbrook, M., Hughes, B., Higgs, G.A., Page, C.P.

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Effects of theophylline and rolipram on antigen‐induced airway responses in neonatally immunized rabbits von Gozzard, N., Herd, C.M., Blake, S.M., Holbrook, M., Hughes, B., Higgs, G.A., Page, C.P.

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Certolizumab Pegol and Adalimumab Accumulation in the Inflammed Paws of Mice with Collagen-induced Arthritis Compared to Noninflammed Tissue In Vivo Biofluorescence Imaging of Alex... von Palframan, Roger, Senior Group Leader, UCB Celltech, Pharmacology, Slough, UK, Vugler, Alex, Research Scientist, UCB Celltech, Pharmacology, Slough, UK, Moore, Adrian, Senior Group Leader, UCB Celltech, Pharmacology, Slough, UK, Baker, Mark, Research Scientist, UCB Celltech, Clinical Pharmacology and Experimental Medicine, Slough, UK, Lightwood, Daniel, Group Leader, UCB Celltech, Antibody Biology, Slough, UK, Nesbitt, Andrew, Senior Group Leader, UCB Celltech, Inflammation Discovery, Slough, UK, Foulkes, Roly, Director, UCB Celltech, Non-clinical Development/Inflammation Therapeutic Area, Slough, UK, Gozzard, Neil, Director, UCB Celltech, Pharmacology, Slough, UK

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Discovery and evaluation of potent, tyrosine-based alpha4beta1 integrin antagonists von Archibald, S C, Head, J C, Gozzard, N, Howat, D W, Parton, T A, Porter, J R, Robinson, M K, Shock, A, Warrellow, G J, Abraham, W M

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The RA-MAP Consortium: a working model for academia-industry collaboration von Cope, AP, Barnes, MR, Belson, A, Binks, M, Brockbank, S, Bonachela-Capdevila, F, Carini, C, Fisher, BA, Goodyear, CS, Emery, P, Ehrenstein, MR, Gozzard, N, Harris, R, Hollis, S, Keidel, S, Levesque, M, Lindholm, C, McDermott, MF, McInnes, IB, Mela, CM, Parker, G, Read, S, Pedersen, AW, Ponchel, F, Porter, D, Rao, R, Rowe, A, Schulze-Knappe, P, Sleeman, MA, Symmons, D, Taylor, PC, Tom, B, Tsuji, W, Verbeeck, D, Isaacs, JD, RA-MAP Consortium

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The RA-MAP Consortium: A working model for academia-industry collaboration von Cope, AP, Barnes, MR, Belson, A, Binks, M, Brockbank, S, Bonachela-Capdevila, F, Carini, C, Fisher, BA, Goodyear, CS, Emery, P, Ehrenstein, MR, Gozzard, N, Harris, R, Hollis, S, Keidel, S, Levesque, M, Lindholm, C, McDermott, MF, McInnes, IB, Mela, CM, Parker, G, Read, S, Pedersen, AW, Ponchel, F, Porter, D, Rao, R, Rowe, A, Schulz-Knappe, P, Sleeman, MA, Symmons, D, Taylor, PC, Tom, B, Tsuji, W, Verbeeck, D, Isaacs, JD, The RA-MAP Consortium

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Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data von Tom, BDM, Carini, C, Cope, AP, Fisher, BA, Goodyear, CS, Gozzard, N, Hollis, S, McInnes, IB, Parker, G, Pedersen, AW, Ponchel, F, Sabin, T, Scott, DL, Taylor, PC, Tsuji, W, Zhong, Y, Lendrem, D, Smith, G, Allen, B, Casement, J, Diboll, J, Harry, R, Simpson, G, Toward, R, Parke, A, Wu, W, Clarke, F, Lempp, H, Ibrahim, F, Molyneux, G, Donnelly, I, Gilmour, A, Virlan, AT, Porter, D, Emery, P, El-Jawhari, J, Parmar, R, McDermot, MF, Buch, M, Buckley, C, Young, SP, Jones, P, Filer, A, Pitzalis, C, Watson, DS, Tzanis, E, Thorborn, G, Kelly, S, Humby, F, Bombardieri, M, Rana, S, Goldmann, K, Lewis, M, John, C, Nguyen, D, Ali, H, Ciurtin, C, Bruce, IN, Verstappen, SMM, Keidel, S, Levesque, M, Long, A, Liu, Z, Lipsky, S, Harvey, B, Macoritto, M, Hong, F, Kaymakcalan, S, Ward, N, Talbot, S, Finch, D, Herath, A, Jenkins, M, Marshall, C, Page, M, Edwards, H, Rowe, A, Capdevila, FB, Loza, M, Curran, M, Verbeeck, D, Baker, D, Vranic, I, Wright, S, Rowell, L, Vernon, E, Joseph, N, Rao, R, Binks, M, Belson, A, Ludbrook, V, Tipney, H, Ellis, J, Haynes, A, Maciejewski, M, Schulz-Knappe, P, Zucht, H-D, Coles, MC, Read, S, Consortium, RA-MAP

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High-precision optical-frequency dissemination on branching optical-fiber networks von Schediwy, Sascha W, Gozzard, David, Baldwin, Kenneth G H, Orr, Brian J, Warrington, R Bruce, Aben, Guido, Luiten, Andre N

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IL-17–high asthma with features of a psoriasis immunophenotype von Schofield, James P.R., Ward, Jonathan, Montuschi, Paolo, Auffray, Charles, Adcock, Ian M., Howarth, Peter, Vaarala, Outi, Bates, S., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Bucchioni, E., Burg, D., Compton, C.H., Corfield, J., D'Amico, A., Dahlen, S.E., Fichtner, K., Fitch, N., Fowler, S.J., Frey, U., Gahlemann, M., Hashimoto, S., Hedlin, G., Knox, A.J., Lutter, R., Middelveld, R.J.M., Mores, N., Myles, D., Pavlidis, S., Rao, M. Puig N., Rowe, A., Sandström, T., Sigmund, R., Singer, F., Sousa, A.R., Sun, K., Thornton, B., van Aalderen, W.M., Vestbo, J., Wilson, S.J., Badorrek, P., Barber, Clair, Batuwitage, Manohara Kanangana, Berton, A., Bochenek, Grazyna, Dahlén, B., De Alba, Jorge, Dekker, Tamara, Dennison, P., Dodson, Paul, Edwards, Jessica, Emma, Rosalia, Flood, Breda, Guillmant-Farry, E., Hewitt, Lorraine, Hu, X., Johnson, K., Klüglich, M., Kots, Maxim, Kuo, Scott, Lambrecht, Bart, Lantz, A.-S., Latzin, P., Lemonnier, N., Lone-Latif, Saeeda, Manta, Alexander, Martin, Jane, Metcalf, Leanne, Mikus, Maria, Monk, Philip, Nething, K., Nicholas, Ben, Niven, R., Nordlund, B., Nsubuga, S., Palkonen, Susanna, Pellet, J., Pennazza, Giorgio, Petrén, Anne, Pink, Sandy, Rahman-Amin, Malayka, Reynolds, Leanne, Robberechts, Martine, Russell, Kirsty, Rutgers, Michael, Santini, G., Saqi, M., Scott, S., Smith, Katherine M., Stephan, S., Strandberg, K., Szentkereszty, M., Tariq, K., Thorsen, Jonathan, van Drunen, C.M., Wetzel, Kristiane, Wiegman, Coen, Yeyasingham, Elizabeth, Zetterquist, W.

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