A Generic Model for Quantitative Prediction of Interactions Mediated by Efflux Transporters and Cytochromes: Application to P-Glycoprotein and Cytochrome 3A4 von Tod, Michel, Goutelle, S., Bleyzac, N., Bourguignon, L.

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A Model for Predicting the Interindividual Variability of Drug-Drug Interactions von Tod, M., Bourguignon, L., Bleyzac, N., Goutelle, S.

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Population modeling and simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of isoniazid in lungs von Lalande, L, Bourguignon, L, Bihari, S, Maire, P, Neely, M, Jelliffe, R, Goutelle, S

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Factors associated with changes in exposure to anticholinergic and sedative medications in elderly hospitalized patients: multicentre longitudinal study von Dauphinot, V., Faure, R., Bourguignon, L., Goutelle, S., Krolak‐Salmon, P., Mouchoux, C.

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Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children von Philippe, M, Goutelle, S, Guitton, J, Fonrose, X, Bergeron, C, Girard, P, Bertrand, Y, Bleyzac, N

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Genotype-Based Quantitative Prediction of Drug Exposure for Drugs Metabolized by CYP2D6 von Tod, M, Goutelle, S, Gagnieu, M C

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Estimating renal function when adjusting the dosage of antibiotics: Facts and fables von Goutelle, S., Bleyzac, N., Mioux, L., de la Gastine, B., Bourguignon, L.

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Peripheral neuropathy with hypervitaminosis B6 caused by self-medication von Malet, L., Dayot, L., Moussy, M., de la Gastine, B., Goutelle, S.

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Suboptimal exposure to fluconazole in critically ill patients: Pharmacokinetic analysis and determinants von Bienvenu, A.L., Pradat, P., Matusik, E., Piriou, V., Rimmelé, T., Parant, F., Tod, M., Leboucher, G., Goutelle, S., Ader, Florence, Argaud, Laurent, Aubrun, Frédéric, Fellahi, Jean-Luc, Guichon, Céline, Juillard, Laurent, Leclerc, Vincent, Miossec, Charline, Paillet, Carole, Plesa, Alexandra, Richard, Jean-Christophe, Roux, Sandrine, Wallet, Florent

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Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is it Worth It? von Tod, M, Goutelle, S, Bourguignon, L, Bleyzac, N

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Improved outcome of children transplanted for high-risk leukemia by using a new strategy of cyclosporine-based GVHD prophylaxis von Bleyzac, N, Cuzzubbo, D, Rénard, C, Garnier, N, Dubois, V, Domenech, C, Goutagny, M-P, Plesa, A, Grardel, N, Goutelle, S, Janoly-Duménil, A, Bertrand, Y

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Prescriptions analysis by clinical pharmacists in the post-operative period: a 4-year prospective study von CHARPIAT, B., GOUTELLE, S., SCHOEFFLER, M., AUBRUN, F., VIALE, J.-P., DUCERF, C., LEBOUCHER, G., ALLENET, B.

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Pharmacokinetic risk factors of beta-blockers overdose in the elderly: Case report and pharmacology approach von Lafarge, L., Bourguignon, L., Bernard, N., Vial, T., Dehan-Moya, M.-J., de la Gastine, B., Goutelle, Sylvain

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Lower limb edema during valpromide treatment: case report and literature review von Gabriel, L, Darcissac, C, Goutelle, S, Sève, P, Vial, T, de La Gastine, B

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Subcutaneous administration of levetiracetam in geriatrics von Maison, O, De la Gastine, B, Peter-Derex, L, Berger, C, Goutelle, S

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Microbiologic epidemiology depending on time to occurrence of prosthetic joint infection: a prospective cohort study von Triffault-Fillit, C., Ferry, T., Laurent, F., Pradat, P., Dupieux, C., Conrad, A., Becker, A., Lustig, S., Fessy, M.H., Chidiac, C., Valour, F., Ferry, T., Valour, F., Perpoint, T., Boibieux, A., Biron, F., Miailhes, P., Ader, F., Becker, A., Roux, S., Triffault-Fillit, C., Daoud, F., Lippman, J., Braun, E., Chidiac, C., Gillet, Y., Hees, L., Lustig, S., Servien, E., Herry, Y., Gaillard, R., Schneider, A., Fessy, M.-H., Viste, A., Chaudier, P., Desmarchelier, R., Mouton, T., Courtin, C., Louboutin, L., Martres, S., Trouillet, F., Barrey, C., Signorelli, F., Jouanneau, E., Jacquesson, T., Mojallal, A., Boucher, F., Shipkov, H., Château, J., Aubrun, F., Bobineau, I., Macabéo, C., Laurent, F., Vandenesch, F., Rasigade, J.-P., Dupieux, C., Craighero, F., Boussel, L., Pialat, J.-B., Morelec, I., Janier, M., Giammarile, F., Tod, M., Gagnieu, M.-C., Goutelle, S., Gerbier-Colomban, S., Benet, T., Mabrut, E., Pradat, P.

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Association between voriconazole exposure and Sequential Organ Failure Assessment (SOFA) score in critically ill patients von Bienvenu, Anne-Lise, Pradat, Pierre, Plesa, Alexandra, Leclerc, Vincent, Piriou, Vincent, Fellahi, Jean-Luc, Argaud, Laurent, Rimmele, Thomas, Menotti, Jean, Aubrun, Frederic, Richard, Jean-Christophe, Gagnieu, Marie-Claude, Parant, Francois, Chidiac, Christian, Leboucher, Gilles, Tod, Michel, Goutelle, Sylvain

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How to estimate renal function for drug dosage adjustment in geriatrics? Comments on the article by Andro et al von Goutelle, S, Lalande, L, Maire, P, Bourguignon, L

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Subcutaneous suppressive antibiotic therapy for bone and joint infections: safety and outcome in a cohort of 10 patients von Pouderoux, Cécile, Becker, Agathe, Goutelle, Sylvain, Lustig, Sébastien, Triffault-Fillit, Claire, Daoud, Fatiha, Fessy, Michel Henry, Cohen, Sabine, Laurent, Frédéric, Chidiac, Christian, Valour, Florent, Ferry, Tristan

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P153 Population PK analysis and dosing simulation of tobramycin in paediatric patients with cystic fibrosis von Praet, A., Vételé, F., Bréant, V., Dumitrescu, O., Doléans-Jordheim, A., Reix, P., Bourguignon, L., Goutelle, S.

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